Gene name: MPE1
Reference locus (S288C): YKL059C
Gene biotype: protein_coding
Description: Protein MPE1; Essential conserved subunit of CPF cleavage and polyadenylation factor; plays a role in 3' end formation of mRNA via the specific cleavage and polyadenylation of pre-mRNA; contains a ubiquitin-like (UBL) domain, a RNA-binding zinc knuckle motif and a RING finger domain; both the zinc knuckle and RING finger are required for pre-mRNA binding; possible role in ubiquitination of Pap1p; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): REF2 (0.999); PTI1 (0.999); PTA1 (0.999); PAP1 (0.999); GLC7 (0.999); SWD2 (0.999); YSH1 (0.999); CFT2 (0.999); FIP1 (0.999); CFT1 (0.999); YTH1 (0.999); PFS2 (0.999); SSU72 (0.999); IPA1 (0.999); PCF11 (0.998); RNA14 (0.994); SYC1 (0.992); RNA15 (0.986); CLP1 (0.947); HRP1 (0.911)
Homologues (species, bitscore): RBBP6 (Homo sapiens, 159.5); Rbbp6 (Mus musculus, 161.0); rbbp6 (Danio rerio, 151.8); rbbp6 (Xenopus tropicalis, 154.8); snama (Drosophila melanogaster, 114.4); tag-214 (Caenorhabditis elegans, 103.2); AT5G47430 (Arabidopsis thaliana, 138.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:314093-315418:- | gene-YKL059C_AKU4011 | rna-NM_001179625.1_AKU4011 | cds-NP_012864.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:328534-329859:+ | gene-YKL059C_BG1 | rna-NM_001179625.1_BG1 | cds-NP_012864.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:333132-334457:- | gene-YKL059C_Bruggeman | rna-NM_001179625.1_Bruggeman | cds-NP_012864.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:329569-330894:- | gene-YKL059C_CAT1 | rna-NM_001179625.1_CAT1 | cds-NP_012864.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:326823-328148:- | gene-YKL059C_CBS1585 | rna-NM_001179625.1_CBS1585 | cds-NP_012864.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:324977-326302:- | gene-YKL059C_CBS436 | rna-NM_001179625.1_CBS436 | cds-NP_012864.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:310964-312289:- | gene-YKL059C_CBS6412 | rna-NM_001179625.1_CBS6412 | cds-NP_012864.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:326789-328114:- | gene-YKL059C_CBS6413 | rna-NM_001179625.1_CBS6413 | cds-NP_012864.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:327779-329104:- | gene-YKL059C_CENPK1137D | rna-NM_001179625.1_CENPK1137D | cds-NP_012864.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:324797-326122:- | gene-YKL059C_EthanolRed | rna-NM_001179625.1_EthanolRed | cds-NP_012864.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:325610-326935:- | gene-YKL059C_FaliES1 | rna-NM_001179625.1_FaliES1 | cds-NP_012864.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000080.1:30539-31864:- | gene-YKL059C_JAY291 | rna-NM_001179625.1_JAY291 | cds-NP_012864.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:334043-335368:- | gene-YKL059C_MUCL30387 | rna-NM_001179625.1_MUCL30387 | cds-NP_012864.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:328942-330267:- | gene-YKL059C_MUCL30388 | rna-NM_001179625.1_MUCL30388 | cds-NP_012864.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:326119-327444:- | gene-YKL059C_MUCL39482 | rna-NM_001179625.1_MUCL39482 | cds-NP_012864.1_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:331029-332354:- | gene-YKL059C_MUCL42920 | rna-NM_001179625.1_MUCL42920 | cds-NP_012864.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:328107-329432:- | gene-YKL059C_NCIM3186 | rna-NM_001179625.1_NCIM3186 | cds-NP_012864.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:326316-327641:- | gene-YKL059C_NCYC1407 | rna-NM_001179625.1_NCYC1407 | cds-NP_012864.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:350880-352205:- | gene-YKL059C_PE2H3 | rna-NM_001179625.1_PE2H3 | cds-NP_012864.1_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:335620-336945:- | gene-YKL059C_PE2H4 | rna-NM_001179625.1_PE2H4 | cds-NP_012864.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:328118-329443:- | gene-YKL059C_S288C | rna-NM_001179625.1_S288C | cds-NP_012864.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000027.1:6119-7444:- | gene-YKL059C_SA1 | rna-NM_001179625.1_SA1 | cds-NP_012864.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:326800-328125:- | gene-YKL059C_ThermosaccDry | rna-NM_001179625.1_ThermosaccDry | cds-NP_012864.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:325945-327270:- | gene-YKL059C_VR1 | rna-NM_001179625.1_VR1 | cds-NP_012864.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:324845-326170:- | gene-YKL059C_ZTW1 | rna-NM_001179625.1_ZTW1 | cds-NP_012864.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:344035-345360:- | gene-YKL059C_Sparadoxus | rna-NM_001179625.1_Sparadoxus | cds-NP_012864.1_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |