MPD1 (YOR288C)


Gene profile

Gene name: MPD1
Reference locus (S288C): YOR288C
Gene biotype: protein_coding

Description: Protein disulfide-isomerase MPD1; Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone activity of Cne1p; MPD1 overexpression in a pdi1 null mutant suppresses defects in Pdi1p functions such as carboxypeptidase Y maturation

Top 10 interactors (score): ERO1 (0.981); KAR2 (0.981); EPS1 (0.955); PDI1 (0.947); MPD2 (0.945); CNE1 (0.869); EUG1 (0.791); LHS1 (0.757); MAM3 (0.724); WBP1 (0.707); ERV29 (0.699); SEC63 (0.695); SIL1 (0.685); SEC62 (0.68); SPC3 (0.667); YBR220C (0.635); YBR219C (0.635); GLR1 (0.632); SRP101 (0.574); TOA1 (0.574)

Homologues (species, bitscore): PDIA6 (Homo sapiens, 99.0); Pdia6 (Mus musculus, 107.8); pdip5 (Danio rerio, 106.3); pdia6 (Xenopus tropicalis, 107.5); CaBP1 (Drosophila melanogaster, 94.7); tag-320 (Caenorhabditis elegans, 93.2); PDIL2-2 (Arabidopsis thaliana, 98.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:842928-843884:- gene-YOR288C_AKU4011 rna-NM_001183707.3_AKU4011 cds-NP_014931.3_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:244889-245845:- gene-YOR288C_BG1 rna-NM_001183707.3_BG1 cds-NP_014931.3_BG1 99.5 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:828360-829316:- gene-YOR288C_Bruggeman rna-NM_001183707.3_Bruggeman cds-NP_014931.3_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:829031-829987:- gene-YOR288C_CAT1 rna-NM_001183707.3_CAT1 cds-NP_014931.3_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:825946-826902:- gene-YOR288C_CBS1585 rna-NM_001183707.3_CBS1585 cds-NP_014931.3_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:824592-825548:- gene-YOR288C_CBS436 rna-NM_001183707.3_CBS436 cds-NP_014931.3_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:822799-823755:- gene-YOR288C_CBS6412 rna-NM_001183707.3_CBS6412 cds-NP_014931.3_CBS6412 99.5 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:831657-832613:- gene-YOR288C_CBS6413 rna-NM_001183707.3_CBS6413 cds-NP_014931.3_CBS6413 99.5 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:851910-852866:- gene-YOR288C_CENPK1137D rna-NM_001183707.3_CENPK1137D cds-NP_014931.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:819055-820011:- gene-YOR288C_EthanolRed rna-NM_001183707.3_EthanolRed cds-NP_014931.3_EthanolRed 99.6 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:824454-825410:- gene-YOR288C_FaliES1 rna-NM_001183707.3_FaliES1 cds-NP_014931.3_FaliES1 99.6 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:1505-2461:+ gene-YOR288C_JAY291 rna-NM_001183707.3_JAY291 cds-NP_014931.3_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:832598-833554:- gene-YOR288C_MUCL30387 rna-NM_001183707.3_MUCL30387 cds-NP_014931.3_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:840576-841532:- gene-YOR288C_MUCL30388 rna-NM_001183707.3_MUCL30388 cds-NP_014931.3_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:833292-834248:- gene-YOR288C_MUCL39482 rna-NM_001183707.3_MUCL39482 cds-NP_014931.3_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:842776-843732:- gene-YOR288C_MUCL42920 rna-NM_001183707.3_MUCL42920 cds-NP_014931.3_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:852010-852966:- gene-YOR288C_NCIM3186 rna-NM_001183707.3_NCIM3186 cds-NP_014931.3_NCIM3186 93.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:833497-834453:- gene-YOR288C_NCYC1407 rna-NM_001183707.3_NCYC1407 cds-NP_014931.3_NCYC1407 99.5 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:832571-833527:- gene-YOR288C_PE2H3 rna-NM_001183707.3_PE2H3 cds-NP_014931.3_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:842952-843908:- gene-YOR288C_PE2H4 rna-NM_001183707.3_PE2H4 cds-NP_014931.3_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:852121-853077:- gene-YOR288C_S288C rna-NM_001183707.3_S288C cds-NP_014931.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:262133-263089:- gene-YOR288C_SA1 rna-NM_001183707.3_SA1 cds-NP_014931.3_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:823637-824593:- gene-YOR288C_ThermosaccDry rna-NM_001183707.3_ThermosaccDry cds-NP_014931.3_ThermosaccDry 99.6 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:887012-887968:- gene-YOR288C_VR1 rna-NM_001183707.3_VR1 cds-NP_014931.3_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:556525-557481:- gene-YOR288C_ZTW1 rna-NM_001183707.3_ZTW1 cds-NP_014931.3_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:829296-830252:- gene-YOR288C_Sparadoxus rna-NM_001183707.3_Sparadoxus cds-NP_014931.3_Sparadoxus 89.4 100.0 Verified 1 1 1 False True False False False

Additional files