Gene name: MPC2
Reference locus (S288C): YHR162W
Gene biotype: protein_coding
Description: Highly conserved subunit of the mitochondrial pyruvate carrier (MPC); expressed during growth on fermentable carbon sources, and heterodimerizes with Mpc1p to form the fermentative isoform of MPC; MPC localizes to the mitochondrial inner membrane and mediates pyruvate uptake; MPC2 paralog, MPC3, heterodimerizes with Mpc1p to form the respiratory MPC isoform
Top 10 interactors (score): MPC1 (0.996); CRC1 (0.959); RIP1 (0.929); COX6 (0.847); QCR2 (0.839); ATP4 (0.78); YAT2 (0.748); YIA6 (0.744); QCR7 (0.71); ACH1 (0.591); YPR011C (0.578); ALT2 (0.574); ACS2 (0.573); YHR140W (0.57); YFR045W (0.568); YEA6 (0.566); YPQ2 (0.561); ATP7 (0.537); ATP20 (0.528); ACS1 (0.527)
Homologues (species, bitscore): MPC2 (Homo sapiens, 91.3); Mpc2 (Mus musculus, 90.5); mpc2 (Danio rerio, 94.4); mpc2 (Xenopus tropicalis, 94.0); CG9396 (Drosophila melanogaster, 99.4); F53F10.3 (Caenorhabditis elegans, 101.3); AT4G22310 (Arabidopsis thaliana, 89.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005302.1:410165-410554:+ | gene-YHR162W_AKU4011 | rna-NM_001179293.1_AKU4011 | cds-NP_012032.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000141.1:107184-107573:- | gene-YHR162W_BG1 | rna-NM_001179293.1_BG1 | cds-NP_012032.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005510.1:417406-417795:+ | gene-YHR162W_Bruggeman | rna-NM_001179293.1_Bruggeman | cds-NP_012032.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005526.1:412811-413200:+ | gene-YHR162W_CAT1 | rna-NM_001179293.1_CAT1 | cds-NP_012032.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005366.1:409622-410011:+ | gene-YHR162W_CBS1585 | rna-NM_001179293.1_CBS1585 | cds-NP_012032.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005350.1:407067-407456:+ | gene-YHR162W_CBS436 | rna-NM_001179293.1_CBS436 | cds-NP_012032.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005334.1:410075-410464:+ | gene-YHR162W_CBS6412 | rna-NM_001179293.1_CBS6412 | cds-NP_012032.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005318.1:410502-410891:+ | gene-YHR162W_CBS6413 | rna-NM_001179293.1_CBS6413 | cds-NP_012032.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001529.1:416244-416633:+ | gene-YHR162W_CENPK1137D | rna-NM_001179293.1_CENPK1137D | cds-NP_012032.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005478.1:468716-469105:+ | gene-YHR162W_EthanolRed | rna-NM_001179293.1_EthanolRed | cds-NP_012032.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005542.1:411159-411548:+ | gene-YHR162W_FaliES1 | rna-NM_001179293.1_FaliES1 | cds-NP_012032.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000017.1:28293-28682:- | gene-YHR162W_JAY291 | rna-NM_001179293.1_JAY291 | cds-NP_012032.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005414.1:418477-418866:+ | gene-YHR162W_MUCL30387 | rna-NM_001179293.1_MUCL30387 | cds-NP_012032.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005446.1:417916-418305:+ | gene-YHR162W_MUCL30388 | rna-NM_001179293.1_MUCL30388 | cds-NP_012032.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005286.1:409533-409922:+ | gene-YHR162W_MUCL39482 | rna-NM_001179293.1_MUCL39482 | cds-NP_012032.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005430.1:416134-416523:+ | gene-YHR162W_MUCL42920 | rna-NM_001179293.1_MUCL42920 | cds-NP_012032.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011817.1:422954-423343:+ | gene-YHR162W_NCIM3186 | rna-NM_001179293.1_NCIM3186 | cds-NP_012032.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005270.1:411991-412380:+ | gene-YHR162W_NCYC1407 | rna-NM_001179293.1_NCYC1407 | cds-NP_012032.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994147.1:411136-411525:+ | gene-YHR162W_PE2H3 | rna-NM_001179293.1_PE2H3 | cds-NP_012032.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999879.1:418563-418952:+ | gene-YHR162W_PE2H4 | rna-NM_001179293.1_PE2H4 | cds-NP_012032.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001140.6:423072-423461:+ | gene-YHR162W_S288C | rna-NM_001179293.1_S288C | cds-NP_012032.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000070.1:28355-28744:- | gene-YHR162W_SA1 | rna-NM_001179293.1_SA1 | cds-NP_012032.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005494.1:412242-412631:+ | gene-YHR162W_ThermosaccDry | rna-NM_001179293.1_ThermosaccDry | cds-NP_012032.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005462.1:420059-420448:+ | gene-YHR162W_VR1 | rna-NM_001179293.1_VR1 | cds-NP_012032.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000017.1:402482-402871:+ | gene-YHR162W_ZTW1 | rna-NM_001179293.1_ZTW1 | cds-NP_012032.1_ZTW1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047494.1:408583-408972:+ | gene-YHR162W_Sparadoxus | rna-NM_001179293.1_Sparadoxus | cds-NP_012032.1_Sparadoxus | 94.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |