Gene name: MOT3
Reference locus (S288C): YMR070W
Gene biotype: protein_coding
Description: Transcriptional activator/repressor MOT3; Transcriptional repressor, activator; role in cellular adjustment to osmotic stress including modulation of mating efficiency; involved in repression of subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, ergosterol biosynthetic genes in response to hyperosmotic stress; contributes to recruitment of Tup1p-Cyc8p general repressor to promoters; relocalizes to cytosol under hypoxia; forms [MOT3+] prion under anaerobic conditions
Top 10 interactors (score): ROX1 (0.983); CYC8 (0.958); ECM22 (0.924); URE2 (0.902); SWI1 (0.898); SUP35 (0.88); UPC2 (0.861); TUP1 (0.852); LEU2 (0.85); RNQ1 (0.84); LEU3 (0.787); DAN1 (0.779); IXR1 (0.758); SFP1 (0.758); MOD5 (0.757); HSP104 (0.755); ANB1 (0.738); GCN4 (0.727); HEM13 (0.724); NEW1 (0.718)
Homologues (species, bitscore): PLAGL1 (Homo sapiens, 61.6); Plag1 (Mus musculus, 60.5); plag1 (Danio rerio, 57.4); plag1 (Xenopus tropicalis, 58.9); dar1 (Drosophila melanogaster, 65.9); TFIIIA (Arabidopsis thaliana, 50.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005307.1:446863-448332:+ | gene-YMR070W_AKU4011 | rna-NM_001182568.1_AKU4011 | cds-NP_013786.1_AKU4011 | 97.2 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000201.1:94455-95918:- | gene-YMR070W_BG1 | rna-NM_001182568.1_BG1 | cds-NP_013786.1_BG1 | 99.2 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005515.1:389029-390483:+ | gene-YMR070W_Bruggeman | rna-NM_001182568.1_Bruggeman | cds-NP_013786.1_Bruggeman | 97.6 | 98.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005531.1:389371-390843:+ | gene-YMR070W_CAT1 | rna-NM_001182568.1_CAT1 | cds-NP_013786.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005371.1:379806-381275:+ | gene-YMR070W_CBS1585 | rna-NM_001182568.1_CBS1585 | cds-NP_013786.1_CBS1585 | 97.1 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005355.1:385362-386825:+ | gene-YMR070W_CBS436 | rna-NM_001182568.1_CBS436 | cds-NP_013786.1_CBS436 | 99.0 | 99.3 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:493206-494348:+ | gene-YMR070W_CBS6412 | rna-NM_001182568.1_CBS6412 | cds-NP_013786.1_CBS6412 | 76.4 | 77.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005323.1:379063-380532:+ | gene-YMR070W_CBS6413 | rna-NM_001182568.1_CBS6413 | cds-NP_013786.1_CBS6413 | 97.2 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001534.1:403259-404731:+ | gene-YMR070W_CENPK1137D | rna-NM_001182568.1_CENPK1137D | cds-NP_013786.1_CENPK1137D | 98.6 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005483.1:379671-381137:+ | gene-YMR070W_EthanolRed | rna-NM_001182568.1_EthanolRed | cds-NP_013786.1_EthanolRed | 97.4 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005547.1:382840-384303:+ | gene-YMR070W_FaliES1 | rna-NM_001182568.1_FaliES1 | cds-NP_013786.1_FaliES1 | 97.6 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000033.1:52654-54116:- | gene-YMR070W_JAY291 | rna-NM_001182568.1_JAY291 | cds-NP_013786.1_JAY291 | 99.1 | 99.3 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005419.1:384772-386214:+ | gene-YMR070W_MUCL30387 | rna-NM_001182568.1_MUCL30387 | cds-NP_013786.1_MUCL30387 | 96.9 | 97.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005451.1:389442-390902:+ | gene-YMR070W_MUCL30388 | rna-NM_001182568.1_MUCL30388 | cds-NP_013786.1_MUCL30388 | 98.0 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005291.1:380094-381563:+ | gene-YMR070W_MUCL39482 | rna-NM_001182568.1_MUCL39482 | cds-NP_013786.1_MUCL39482 | 97.1 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005435.1:386750-388216:+ | gene-YMR070W_MUCL42920 | rna-NM_001182568.1_MUCL42920 | cds-NP_013786.1_MUCL42920 | 97.5 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011822.1:409108-410580:+ | gene-YMR070W_NCIM3186 | rna-NM_001182568.1_NCIM3186 | cds-NP_013786.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005275.1:380006-381475:+ | gene-YMR070W_NCYC1407 | rna-NM_001182568.1_NCYC1407 | cds-NP_013786.1_NCYC1407 | 97.3 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994152.1:385960-387423:+ | gene-YMR070W_PE2H3 | rna-NM_001182568.1_PE2H3 | cds-NP_013786.1_PE2H3 | 99.1 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999884.1:392055-393518:+ | gene-YMR070W_PE2H4 | rna-NM_001182568.1_PE2H4 | cds-NP_013786.1_PE2H4 | 99.1 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001145.3:409154-410626:+ | gene-YMR070W_S288C | rna-NM_001182568.1_S288C | cds-NP_013786.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000005.1:139544-140995:- | gene-YMR070W_SA1 | rna-NM_001182568.1_SA1 | cds-NP_013786.1_SA1 | 98.3 | 98.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005499.1:380643-382106:+ | gene-YMR070W_ThermosaccDry | rna-NM_001182568.1_ThermosaccDry | cds-NP_013786.1_ThermosaccDry | 97.6 | 98.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005467.1:392546-394009:+ | gene-YMR070W_VR1 | rna-NM_001182568.1_VR1 | cds-NP_013786.1_VR1 | 99.3 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000027.1:358920-360380:+ | gene-YMR070W_ZTW1 | rna-NM_001182568.1_ZTW1 | cds-NP_013786.1_ZTW1 | 98.5 | 99.1 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047499.1:392484-393950:+ | gene-YMR070W_Sparadoxus | rna-NM_001182568.1_Sparadoxus | cds-NP_013786.1_Sparadoxus | 83.0 | 97.6 | Verified | 1 | 1 | 1 | False | True | False | False | False |