Gene name: MOT1
Reference locus (S288C): YPL082C
Gene biotype: protein_coding
Description: TATA-binding protein-associated factor MOT1; Essential protein involved in regulation of transcription; removes Spt15p (TBP) from DNA via its C-terminal ATPase activity; may have a role in ensuring that soluble TBP is available to bind TATA-less promoters; forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity; the Mot1p-Spt15p-DNA ternary complex contains unbent DNA; coregulates transcription with Spt16p through assembly of preinitiation complex and organization of nucleosomes
Top 10 interactors (score): SPT15 (0.999); BUR6 (0.983); SUA7 (0.966); CDC14 (0.966); GPI8 (0.962); NOP9 (0.962); YTA7 (0.943); NCB2 (0.938); SPT3 (0.937); TAF1 (0.924); BRF1 (0.91); BDP1 (0.897); TAF6 (0.89); SIZ1 (0.882); NFI1 (0.88); TAF2 (0.872); UBA2 (0.864); UBC9 (0.86); ISW1 (0.859); SMT3 (0.85)
Homologues (species, bitscore): BTAF1 (Homo sapiens, 1175.6); Btaf1 (Mus musculus, 1174.5); btaf1 (Danio rerio, 1184.1); btaf1 (Xenopus tropicalis, 916.0); Hel89B (Drosophila melanogaster, 1025.8); btf-1 (Caenorhabditis elegans, 467.6); RGD3 (Arabidopsis thaliana, 971.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:376214-381817:- | gene-YPL082C_AKU4011 | rna-NM_001183896.1_AKU4011 | cds-NP_015243.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000069.1:581899-587502:- | gene-YPL082C_BG1 | rna-NM_001183896.1_BG1 | cds-NP_015243.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:452535-458138:- | gene-YPL082C_Bruggeman | rna-NM_001183896.1_Bruggeman | cds-NP_015243.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:492887-498490:- | gene-YPL082C_CAT1 | rna-NM_001183896.1_CAT1 | cds-NP_015243.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:380281-385884:- | gene-YPL082C_CBS1585 | rna-NM_001183896.1_CBS1585 | cds-NP_015243.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:394835-400438:- | gene-YPL082C_CBS436 | rna-NM_001183896.1_CBS436 | cds-NP_015243.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:384475-390078:- | gene-YPL082C_CBS6412 | rna-NM_001183896.1_CBS6412 | cds-NP_015243.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:376833-382436:- | gene-YPL082C_CBS6413 | rna-NM_001183896.1_CBS6413 | cds-NP_015243.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:398452-404055:- | gene-YPL082C_CENPK1137D | rna-NM_001183896.1_CENPK1137D | cds-NP_015243.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:374581-380184:- | gene-YPL082C_EthanolRed | rna-NM_001183896.1_EthanolRed | cds-NP_015243.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:382411-388014:- | gene-YPL082C_FaliES1 | rna-NM_001183896.1_FaliES1 | cds-NP_015243.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000350.1:3225-8828:+ | gene-YPL082C_JAY291 | rna-NM_001183896.1_JAY291 | cds-NP_015243.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:393366-398969:- | gene-YPL082C_MUCL30387 | rna-NM_001183896.1_MUCL30387 | cds-NP_015243.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:392169-397772:- | gene-YPL082C_MUCL30388 | rna-NM_001183896.1_MUCL30388 | cds-NP_015243.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:373610-379213:- | gene-YPL082C_MUCL39482 | rna-NM_001183896.1_MUCL39482 | cds-NP_015243.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:431473-437076:- | gene-YPL082C_MUCL42920 | rna-NM_001183896.1_MUCL42920 | cds-NP_015243.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:398463-404066:- | gene-YPL082C_NCIM3186 | rna-NM_001183896.1_NCIM3186 | cds-NP_015243.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:380221-385824:- | gene-YPL082C_NCYC1407 | rna-NM_001183896.1_NCYC1407 | cds-NP_015243.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:387494-393097:- | gene-YPL082C_PE2H3 | rna-NM_001183896.1_PE2H3 | cds-NP_015243.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:387117-392720:- | gene-YPL082C_PE2H4 | rna-NM_001183896.1_PE2H4 | cds-NP_015243.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:398480-404083:- | gene-YPL082C_S288C | rna-NM_001183896.1_S288C | cds-NP_015243.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000057.1:20592-26195:- | gene-YPL082C_SA1 | rna-NM_001183896.1_SA1 | cds-NP_015243.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:382211-387814:- | gene-YPL082C_ThermosaccDry | rna-NM_001183896.1_ThermosaccDry | cds-NP_015243.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:397203-402806:- | gene-YPL082C_VR1 | rna-NM_001183896.1_VR1 | cds-NP_015243.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:381520-387123:- | gene-YPL082C_ZTW1 | rna-NM_001183896.1_ZTW1 | cds-NP_015243.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:383177-388783:- | gene-YPL082C_Sparadoxus | rna-NM_001183896.1_Sparadoxus | cds-NP_015243.1_Sparadoxus | 90.1 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |