MNN4 (YKL201C)


Gene profile

Gene name: MNN4
Reference locus (S288C): YKL201C
Gene biotype: protein_coding

Description: Protein MNN4; Putative positive regulator of mannosylphosphate transferase Mnn6p; involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases; coding sequence contains length polymorphisms in different strains; MNN4 has a paralog, YJR061W, that arose from the whole genome duplication

Top 10 interactors (score): KTR6 (0.964); MNN1 (0.934); MNN2 (0.911); OCH1 (0.909); KRE2 (0.829); MPO1 (0.813); MNN5 (0.811); MNT4 (0.747); VPS74 (0.698); MNN9 (0.674); MNN10 (0.62); MNT2 (0.617); TAF1 (0.602); PNO1 (0.573); SVP26 (0.551); MNS1 (0.52); PMR1 (0.514); AMS1 (0.499); ALG5 (0.499); PMT2 (0.489)

Homologues (species, bitscore): WDR87 (Homo sapiens, 65.9); Ankhd1 (Mus musculus, 57.0); pleca (Danio rerio, 69.7); GIGYF2 (Xenopus tropicalis, 84.7); sls (Drosophila melanogaster, 60.1); PMD1 (Arabidopsis thaliana, 50.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:50244-53834:- gene-YKL201C_AKU4011 rna-NM_001179766.1_AKU4011 cds-NP_012721.1_AKU4011 97.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000030.1:27329-30796:- gene-YKL201C_BG1 rna-NM_001179766.1_BG1 cds-NP_012721.1_BG1 97.1 98.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:67916-71479:- gene-YKL201C_Bruggeman rna-NM_001179766.1_Bruggeman cds-NP_012721.1_Bruggeman 98.9 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:63109-66678:- gene-YKL201C_CAT1 rna-NM_001179766.1_CAT1 cds-NP_012721.1_CAT1 97.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:62256-65819:- gene-YKL201C_CBS1585 rna-NM_001179766.1_CBS1585 cds-NP_012721.1_CBS1585 98.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:61458-65027:- gene-YKL201C_CBS436 rna-NM_001179766.1_CBS436 cds-NP_012721.1_CBS436 97.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:47513-51076:- gene-YKL201C_CBS6412 rna-NM_001179766.1_CBS6412 cds-NP_012721.1_CBS6412 98.7 100.0 Unannotated 1 1 0 False False False False True
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:62893-66456:- gene-YKL201C_CBS6413 rna-NM_001179766.1_CBS6413 cds-NP_012721.1_CBS6413 98.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:63711-67250:- gene-YKL201C_CENPK1137D rna-NM_001179766.1_CENPK1137D cds-NP_012721.1_CENPK1137D 99.4 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:61727-65266:- gene-YKL201C_EthanolRed rna-NM_001179766.1_EthanolRed cds-NP_012721.1_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:61786-65325:- gene-YKL201C_FaliES1 rna-NM_001179766.1_FaliES1 cds-NP_012721.1_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000006.2:61402-64869:- gene-YKL201C_JAY291 rna-NM_001179766.1_JAY291 cds-NP_012721.1_JAY291 97.1 98.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:70451-74014:- gene-YKL201C_MUCL30387 rna-NM_001179766.1_MUCL30387 cds-NP_012721.1_MUCL30387 98.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:64539-68102:- gene-YKL201C_MUCL30388 rna-NM_001179766.1_MUCL30388 cds-NP_012721.1_MUCL30388 98.9 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:62313-65876:- gene-YKL201C_MUCL39482 rna-NM_001179766.1_MUCL39482 cds-NP_012721.1_MUCL39482 98.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:65607-69164:- gene-YKL201C_MUCL42920 rna-NM_001179766.1_MUCL42920 cds-NP_012721.1_MUCL42920 98.7 99.9 Unannotated 1 1 0 False False False False True
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:63919-67455:- gene-YKL201C_NCIM3186 rna-NM_001179766.1_NCIM3186 cds-NP_012721.1_NCIM3186 99.3 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:62337-65900:- gene-YKL201C_NCYC1407 rna-NM_001179766.1_NCYC1407 cds-NP_012721.1_NCYC1407 98.7 100.0 Unannotated 1 1 0 False False False False True
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:70036-73407:- gene-YKL201C_PE2H3 rna-NM_001179766.1_PE2H3 cds-NP_012721.1_PE2H3 94.9 95.3 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:66234-69701:- gene-YKL201C_PE2H4 rna-NM_001179766.1_PE2H4 cds-NP_012721.1_PE2H4 97.1 98.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:63930-67466:- gene-YKL201C_S288C rna-NM_001179766.1_S288C cds-NP_012721.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000092.1:430-3942:+ gene-YKL201C_SA1 rna-NM_001179766.1_SA1 cds-NP_012721.1_SA1 97.3 98.6 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:62534-66073:- gene-YKL201C_ThermosaccDry rna-NM_001179766.1_ThermosaccDry cds-NP_012721.1_ThermosaccDry 99.4 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:61640-65107:- gene-YKL201C_VR1 rna-NM_001179766.1_VR1 cds-NP_012721.1_VR1 97.1 98.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:61447-65001:- gene-YKL201C_ZTW1 rna-NM_001179766.1_ZTW1 cds-NP_012721.1_ZTW1 99.0 99.9 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:70171-73662:- gene-YKL201C_Sparadoxus rna-NM_001179766.1_Sparadoxus cds-NP_012721.1_Sparadoxus 87.4 98.5 Verified 1 1 0 False False False True False

Additional files