Gene name: MNL2
Reference locus (S288C): YLR057W
Gene biotype: protein_coding
Description: Mannosyl-oligosaccharide alpha-1,2-mannosidase; Putative endoplasmic reticulum mannosidase MNL2; Putative mannosidase involved in ER-associated protein degradation; localizes to the endoplasmic reticulum; sequence similarity with seven-hairpin glycosidase (GH47) family members, such as Mns1p and Mnl1p, that hydrolyze 1,2-linked alpha-D-mannose residues; non-essential gene
Top 10 interactors (score): MNS1 (0.995); OCH1 (0.913); MNL1 (0.87); TED1 (0.749); WBP1 (0.737); AMS1 (0.718); ROT1 (0.716); YJR015W (0.716); YNL058C (0.712); CWH41 (0.703); YCR061W (0.698); SWP1 (0.694); AIM24 (0.694); YOS9 (0.684); VTH2 (0.68); COY1 (0.672); OAC1 (0.671); KRE5 (0.669); YHC1 (0.624); MNN11 (0.617)
Homologues (species, bitscore): MAN1B1 (Homo sapiens, 64.7); Man1b1 (Mus musculus, 63.5); man1b1a (Danio rerio, 62.8); man1a1 (Xenopus tropicalis, 58.5); CG31202 (Drosophila melanogaster, 61.6); D2030.1 (Caenorhabditis elegans, 64.7); MNS1 (Arabidopsis thaliana, 69.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:237792-240341:+ | gene-YLR057W_AKU4011 | rna-NM_001181944.1_AKU4011 | cds-NP_013158.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:200914-203463:+ | gene-YLR057W_BG1 | rna-NM_001181944.1_BG1 | cds-NP_013158.1_BG1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:247701-250250:+ | gene-YLR057W_Bruggeman | rna-NM_001181944.1_Bruggeman | cds-NP_013158.1_Bruggeman | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:248006-250555:+ | gene-YLR057W_CAT1 | rna-NM_001181944.1_CAT1 | cds-NP_013158.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:244927-247476:+ | gene-YLR057W_CBS1585 | rna-NM_001181944.1_CBS1585 | cds-NP_013158.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:235540-238089:+ | gene-YLR057W_CBS436 | rna-NM_001181944.1_CBS436 | cds-NP_013158.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:243336-245885:+ | gene-YLR057W_CBS6412 | rna-NM_001181944.1_CBS6412 | cds-NP_013158.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:245190-247739:+ | gene-YLR057W_CBS6413 | rna-NM_001181944.1_CBS6413 | cds-NP_013158.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:234564-237113:+ | gene-YLR057W_CENPK1137D | rna-NM_001181944.1_CENPK1137D | cds-NP_013158.1_CENPK1137D | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:237304-239853:+ | gene-YLR057W_EthanolRed | rna-NM_001181944.1_EthanolRed | cds-NP_013158.1_EthanolRed | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:237191-239740:+ | gene-YLR057W_FaliES1 | rna-NM_001181944.1_FaliES1 | cds-NP_013158.1_FaliES1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000129.1:12111-14660:+ | gene-YLR057W_JAY291 | rna-NM_001181944.1_JAY291 | cds-NP_013158.1_JAY291 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:245054-247603:+ | gene-YLR057W_MUCL30387 | rna-NM_001181944.1_MUCL30387 | cds-NP_013158.1_MUCL30387 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:252709-255258:+ | gene-YLR057W_MUCL30388 | rna-NM_001181944.1_MUCL30388 | cds-NP_013158.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:245422-247971:+ | gene-YLR057W_MUCL39482 | rna-NM_001181944.1_MUCL39482 | cds-NP_013158.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:245326-247875:+ | gene-YLR057W_MUCL42920 | rna-NM_001181944.1_MUCL42920 | cds-NP_013158.1_MUCL42920 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:255280-257829:+ | gene-YLR057W_NCIM3186 | rna-NM_001181944.1_NCIM3186 | cds-NP_013158.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:237483-240032:+ | gene-YLR057W_NCYC1407 | rna-NM_001181944.1_NCYC1407 | cds-NP_013158.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:243348-245897:+ | gene-YLR057W_PE2H3 | rna-NM_001181944.1_PE2H3 | cds-NP_013158.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:243089-245638:+ | gene-YLR057W_PE2H4 | rna-NM_001181944.1_PE2H4 | cds-NP_013158.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:255306-257855:+ | gene-YLR057W_S288C | rna-NM_001181944.1_S288C | cds-NP_013158.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000046.1:81160-83709:+ | gene-YLR057W_SA1 | rna-NM_001181944.1_SA1 | cds-NP_013158.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:237376-239925:+ | gene-YLR057W_ThermosaccDry | rna-NM_001181944.1_ThermosaccDry | cds-NP_013158.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:251040-253589:+ | gene-YLR057W_VR1 | rna-NM_001181944.1_VR1 | cds-NP_013158.1_VR1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:236739-239288:+ | gene-YLR057W_ZTW1 | rna-NM_001181944.1_ZTW1 | cds-NP_013158.1_ZTW1 | 99.0 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:245608-248157:+ | gene-YLR057W_Sparadoxus | rna-NM_001181944.1_Sparadoxus | cds-NP_013158.1_Sparadoxus | 88.2 | 99.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |