MMS22 (YLR320W)


Gene profile

Gene name: MMS22
Reference locus (S288C): YLR320W
Gene biotype: protein_coding

Description: E3 ubiquitin-protein ligase substrate receptor MMS22; Subunit of E3 ubiquitin ligase complex involved in replication repair; stabilizes protein components of the replication fork, such as the fork-pausing complex and leading strand polymerase, preventing fork collapse and promoting efficient recovery during replication stress; required for accurate meiotic chromosome segregation; Belongs to the MMS22 family

Top 10 interactors (score): RTT107 (0.999); MMS1 (0.999); RTT101 (0.999); CTF4 (0.993); HRT1 (0.953); RTT109 (0.932); RAD52 (0.848); HHT1 (0.794); ASF1 (0.773); MRC1 (0.761); SRS2 (0.745); CDC45 (0.734); CSM3 (0.72); RRM3 (0.715); HST3 (0.706); TOF1 (0.685); YLR280C (0.675); RAD18 (0.628); RTT106 (0.616); HHT2 (0.609)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:720394-724758:+ gene-YLR320W_AKU4011 rna-NM_001182209.1_AKU4011 cds-NP_013424.1_AKU4011 99.7 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000170.1:7924-12288:- gene-YLR320W_BG1 rna-NM_001182209.1_BG1 cds-NP_013424.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:756227-760591:+ gene-YLR320W_Bruggeman rna-NM_001182209.1_Bruggeman cds-NP_013424.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:754382-758746:+ gene-YLR320W_CAT1 rna-NM_001182209.1_CAT1 cds-NP_013424.1_CAT1 99.7 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:755310-759674:+ gene-YLR320W_CBS1585 rna-NM_001182209.1_CBS1585 cds-NP_013424.1_CBS1585 99.8 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:739910-744274:+ gene-YLR320W_CBS436 rna-NM_001182209.1_CBS436 cds-NP_013424.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:793265-797629:+ gene-YLR320W_CBS6412 rna-NM_001182209.1_CBS6412 cds-NP_013424.1_CBS6412 99.8 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:755982-760346:+ gene-YLR320W_CBS6413 rna-NM_001182209.1_CBS6413 cds-NP_013424.1_CBS6413 99.8 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:756554-760918:+ gene-YLR320W_CENPK1137D rna-NM_001182209.1_CENPK1137D cds-NP_013424.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:713677-718041:+ gene-YLR320W_EthanolRed rna-NM_001182209.1_EthanolRed cds-NP_013424.1_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:742878-747242:+ gene-YLR320W_FaliES1 rna-NM_001182209.1_FaliES1 cds-NP_013424.1_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000296.1:20615-24979:- gene-YLR320W_JAY291 rna-NM_001182209.1_JAY291 cds-NP_013424.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:755453-759817:+ gene-YLR320W_MUCL30387 rna-NM_001182209.1_MUCL30387 cds-NP_013424.1_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:761039-765403:+ gene-YLR320W_MUCL30388 rna-NM_001182209.1_MUCL30388 cds-NP_013424.1_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:756551-760915:+ gene-YLR320W_MUCL39482 rna-NM_001182209.1_MUCL39482 cds-NP_013424.1_MUCL39482 99.8 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:751702-756066:+ gene-YLR320W_MUCL42920 rna-NM_001182209.1_MUCL42920 cds-NP_013424.1_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:771914-776278:+ gene-YLR320W_NCIM3186 rna-NM_001182209.1_NCIM3186 cds-NP_013424.1_NCIM3186 99.7 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:765891-770255:+ gene-YLR320W_NCYC1407 rna-NM_001182209.1_NCYC1407 cds-NP_013424.1_NCYC1407 99.8 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:753674-758038:+ gene-YLR320W_PE2H3 rna-NM_001182209.1_PE2H3 cds-NP_013424.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:753418-757782:+ gene-YLR320W_PE2H4 rna-NM_001182209.1_PE2H4 cds-NP_013424.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:771940-776304:+ gene-YLR320W_S288C rna-NM_001182209.1_S288C cds-NP_013424.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000039.1:8005-12369:- gene-YLR320W_SA1 rna-NM_001182209.1_SA1 cds-NP_013424.1_SA1 99.7 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:744770-749134:+ gene-YLR320W_ThermosaccDry rna-NM_001182209.1_ThermosaccDry cds-NP_013424.1_ThermosaccDry 99.8 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:756890-761254:+ gene-YLR320W_VR1 rna-NM_001182209.1_VR1 cds-NP_013424.1_VR1 99.7 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:83185-87548:+ gene-YLR320W_ZTW1 rna-NM_001182209.1_ZTW1 cds-NP_013424.1_ZTW1 99.7 99.9 Unannotated 1 1 0 False False False True False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:730922-735292:+ gene-YLR320W_Sparadoxus rna-NM_001182209.1_Sparadoxus cds-NP_013424.1_Sparadoxus 86.3 99.9 Verified 1 1 1 False True False False False

Additional files