MMS2 (YGL087C)


Gene profile

Gene name: MMS2
Reference locus (S288C): YGL087C
Gene biotype: protein_coding

Description: Ubiquitin-conjugating enzyme variant; involved in error-free postreplication repair; forms a heteromeric complex with Ubc13p, an active ubiquitin-conjugating enzyme; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p; protein abundance increases in response to DNA replication stress

Top 10 interactors (score): RAD5 (0.999); UBC13 (0.999); RAD6 (0.996); UBC9 (0.996); UBC1 (0.995); REV3 (0.995); UBI4 (0.995); RAD18 (0.991); UBC4 (0.986); UBC12 (0.98); UBC5 (0.98); RAD30 (0.978); REV1 (0.969); RPL40B (0.967); ACB1 (0.96); RAD52 (0.956); POL30 (0.949); RAD51 (0.948); RPS31 (0.946); SRS2 (0.942)

Homologues (species, bitscore): UBE2V2 (Homo sapiens, 155.2); Ube2v2 (Mus musculus, 152.9); ube2v2 (Danio rerio, 148.7); ube2v2 (Xenopus tropicalis, 150.6); Uev1A (Drosophila melanogaster, 143.3); uev-1 (Caenorhabditis elegans, 141.4); MMZ1 (Arabidopsis thaliana, 160.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:349410-349908:- gene-YGL087C_AKU4011 rna-NM_001180952.1_AKU4011 cds-NP_011428.1_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000132.1:55508-56006:+ gene-YGL087C_BG1 rna-NM_001180952.1_BG1 cds-NP_011428.1_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:351903-352401:- gene-YGL087C_Bruggeman rna-NM_001180952.1_Bruggeman cds-NP_011428.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:348796-349294:- gene-YGL087C_CAT1 rna-NM_001180952.1_CAT1 cds-NP_011428.1_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:352735-353233:- gene-YGL087C_CBS1585 rna-NM_001180952.1_CBS1585 cds-NP_011428.1_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:347020-347518:- gene-YGL087C_CBS436 rna-NM_001180952.1_CBS436 cds-NP_011428.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:337116-337614:- gene-YGL087C_CBS6412 rna-NM_001180952.1_CBS6412 cds-NP_011428.1_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:347041-347539:- gene-YGL087C_CBS6413 rna-NM_001180952.1_CBS6413 cds-NP_011428.1_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:346593-347091:- gene-YGL087C_CENPK1137D rna-NM_001180952.1_CENPK1137D cds-NP_011428.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:338495-338993:- gene-YGL087C_EthanolRed rna-NM_001180952.1_EthanolRed cds-NP_011428.1_EthanolRed 99.7 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:341056-341554:- gene-YGL087C_FaliES1 rna-NM_001180952.1_FaliES1 cds-NP_011428.1_FaliES1 99.7 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000369.1:26667-27165:- gene-YGL087C_JAY291 rna-NM_001180952.1_JAY291 cds-NP_011428.1_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:348880-349378:- gene-YGL087C_MUCL30387 rna-NM_001180952.1_MUCL30387 cds-NP_011428.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:351866-352364:- gene-YGL087C_MUCL30388 rna-NM_001180952.1_MUCL30388 cds-NP_011428.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:349263-349761:- gene-YGL087C_MUCL39482 rna-NM_001180952.1_MUCL39482 cds-NP_011428.1_MUCL39482 99.7 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:353791-354289:- gene-YGL087C_MUCL42920 rna-NM_001180952.1_MUCL42920 cds-NP_011428.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:346406-346904:- gene-YGL087C_NCIM3186 rna-NM_001180952.1_NCIM3186 cds-NP_011428.1_NCIM3186 99.7 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:340798-341296:- gene-YGL087C_NCYC1407 rna-NM_001180952.1_NCYC1407 cds-NP_011428.1_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:342433-342931:- gene-YGL087C_PE2H3 rna-NM_001180952.1_PE2H3 cds-NP_011428.1_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:347430-347928:- gene-YGL087C_PE2H4 rna-NM_001180952.1_PE2H4 cds-NP_011428.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:346406-346904:- gene-YGL087C_S288C rna-NM_001180952.1_S288C cds-NP_011428.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000089.1:23787-24285:- gene-YGL087C_SA1 rna-NM_001180952.1_SA1 cds-NP_011428.1_SA1 100.0 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:341309-341807:- gene-YGL087C_ThermosaccDry rna-NM_001180952.1_ThermosaccDry cds-NP_011428.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:451171-451669:- gene-YGL087C_VR1 rna-NM_001180952.1_VR1 cds-NP_011428.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:338663-339161:- gene-YGL087C_ZTW1 rna-NM_001180952.1_ZTW1 cds-NP_011428.1_ZTW1 99.7 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:344318-344803:- gene-YGL087C_Sparadoxus rna-NM_001180952.1_Sparadoxus cds-NP_011428.1_Sparadoxus 90.8 100.0 Verified 1 1 1 False True False False False

Additional files