MMF1 (YIL051C)


Gene profile

Gene name: MMF1
Reference locus (S288C): YIL051C
Gene biotype: protein_coding

Description: Mitochondrial protein required for transamination of isoleucine; but not of valine or leucine; may regulate specificity of branched-chain transaminases Bat1p and Bat2p; induction of expression in response to stress is mediated by a Hog1p-regulated antisense RNA and gene looping; interacts genetically with mitochondrial ribosomal protein genes; MMF1 has a paralog, HMF1, that arose from the whole genome duplication

Top 10 interactors (score): SHM1 (0.766); MAM33 (0.739); LIH1 (0.659); YIL060W (0.653); PEP4 (0.651); MRPL38 (0.65); MCX1 (0.649); MRPL40 (0.648); REX2 (0.613); AIM45 (0.596); CHA1 (0.592); ARF2 (0.579); ILV1 (0.576); AIM19 (0.57); MRX14 (0.568); EMI2 (0.566); TKL2 (0.565); PHO92 (0.561); MRX3 (0.552); TKL1 (0.549)

Homologues (species, bitscore): HRSP12 (Homo sapiens, 90.9); Hrsp12 (Mus musculus, 94.0); hrsp12 (Danio rerio, 74.3); UK114 (Drosophila melanogaster, 86.7); C23G10.2 (Caenorhabditis elegans, 83.6); AT3G20390 (Arabidopsis thaliana, 103.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:254675-255112:- gene-YIL051C_AKU4011 rna-NM_001179401.3_AKU4011 cds-NP_012213.3_AKU4011 99.7 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000164.1:116111-116548:- gene-YIL051C_BG1 rna-NM_001179401.3_BG1 cds-NP_012213.3_BG1 99.7 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:260926-261363:- gene-YIL051C_Bruggeman rna-NM_001179401.3_Bruggeman cds-NP_012213.3_Bruggeman 99.7 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:248588-249025:- gene-YIL051C_CAT1 rna-NM_001179401.3_CAT1 cds-NP_012213.3_CAT1 99.7 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:254500-254937:- gene-YIL051C_CBS1585 rna-NM_001179401.3_CBS1585 cds-NP_012213.3_CBS1585 99.7 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:249798-250235:- gene-YIL051C_CBS436 rna-NM_001179401.3_CBS436 cds-NP_012213.3_CBS436 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:251115-251552:- gene-YIL051C_CBS6412 rna-NM_001179401.3_CBS6412 cds-NP_012213.3_CBS6412 99.7 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:246666-247103:- gene-YIL051C_CBS6413 rna-NM_001179401.3_CBS6413 cds-NP_012213.3_CBS6413 99.7 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:249550-249987:- gene-YIL051C_CENPK1137D rna-NM_001179401.3_CENPK1137D cds-NP_012213.3_CENPK1137D 99.7 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:238589-239026:- gene-YIL051C_EthanolRed rna-NM_001179401.3_EthanolRed cds-NP_012213.3_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:256128-256565:- gene-YIL051C_FaliES1 rna-NM_001179401.3_FaliES1 cds-NP_012213.3_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000365.1:42314-42751:+ gene-YIL051C_JAY291 rna-NM_001179401.3_JAY291 cds-NP_012213.3_JAY291 99.7 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:257818-258255:- gene-YIL051C_MUCL30387 rna-NM_001179401.3_MUCL30387 cds-NP_012213.3_MUCL30387 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:254421-254858:- gene-YIL051C_MUCL30388 rna-NM_001179401.3_MUCL30388 cds-NP_012213.3_MUCL30388 99.5 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:255343-255780:- gene-YIL051C_MUCL39482 rna-NM_001179401.3_MUCL39482 cds-NP_012213.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:258474-258911:- gene-YIL051C_MUCL42920 rna-NM_001179401.3_MUCL42920 cds-NP_012213.3_MUCL42920 99.5 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:257843-258280:- gene-YIL051C_NCIM3186 rna-NM_001179401.3_NCIM3186 cds-NP_012213.3_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:259616-260053:- gene-YIL051C_NCYC1407 rna-NM_001179401.3_NCYC1407 cds-NP_012213.3_NCYC1407 99.7 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:252858-253295:- gene-YIL051C_PE2H3 rna-NM_001179401.3_PE2H3 cds-NP_012213.3_PE2H3 99.7 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:247570-248007:- gene-YIL051C_PE2H4 rna-NM_001179401.3_PE2H4 cds-NP_012213.3_PE2H4 99.7 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:257843-258280:- gene-YIL051C_S288C rna-NM_001179401.3_S288C cds-NP_012213.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000031.1:67889-68326:+ gene-YIL051C_SA1 rna-NM_001179401.3_SA1 cds-NP_012213.3_SA1 99.7 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:254797-255234:- gene-YIL051C_ThermosaccDry rna-NM_001179401.3_ThermosaccDry cds-NP_012213.3_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:251975-252412:- gene-YIL051C_VR1 rna-NM_001179401.3_VR1 cds-NP_012213.3_VR1 99.7 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:228640-229077:- gene-YIL051C_ZTW1 rna-NM_001179401.3_ZTW1 cds-NP_012213.3_ZTW1 99.5 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:250761-251198:- gene-YIL051C_Sparadoxus rna-NM_001179401.3_Sparadoxus cds-NP_012213.3_Sparadoxus 92.2 100.0 Verified 1 1 1 False True False False False

Additional files