MLP2 (YIL149C)


Gene profile

Gene name: MLP2
Reference locus (S288C): YIL149C
Gene biotype: protein_coding

Description: Nucleoprotein tpr; Myosin-like protein associated with the nuclear envelope; nuclear basket protein that connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length; MLP2 has a paralog, MLP1, that arose from the whole genome duplication

Top 10 interactors (score): NUP2 (0.999); NSP1 (0.998); NUP60 (0.998); NUP1 (0.996); MLP1 (0.994); NIC96 (0.988); NUP53 (0.982); MEX67 (0.961); NUP133 (0.958); ULP1 (0.955); NUP192 (0.954); NUP84 (0.951); YRA1 (0.949); NUP159 (0.948); SEH1 (0.945); NUP157 (0.945); MAD1 (0.945); NUP145 (0.93); ASM4 (0.926); NUP85 (0.926)

Homologues (species, bitscore): TPR (Homo sapiens, 61.2); Tpr (Mus musculus, 63.2); tpr (Xenopus tropicalis, 59.3); Mtor (Drosophila melanogaster, 52.8)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005303.1:64249-69288:- gene-YIL149C_AKU4011 rna-NM_001179497.3_AKU4011 cds-NP_012117.3_AKU4011 99.1 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000174.1:68079-73118:+ gene-YIL149C_BG1 rna-NM_001179497.3_BG1 cds-NP_012117.3_BG1 99.2 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005511.1:67009-72048:- gene-YIL149C_Bruggeman rna-NM_001179497.3_Bruggeman cds-NP_012117.3_Bruggeman 99.3 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005527.1:60816-65855:- gene-YIL149C_CAT1 rna-NM_001179497.3_CAT1 cds-NP_012117.3_CAT1 99.1 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005367.1:64452-69491:- gene-YIL149C_CBS1585 rna-NM_001179497.3_CBS1585 cds-NP_012117.3_CBS1585 99.1 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005351.1:55588-60627:- gene-YIL149C_CBS436 rna-NM_001179497.3_CBS436 cds-NP_012117.3_CBS436 99.2 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005335.1:61981-67020:- gene-YIL149C_CBS6412 rna-NM_001179497.3_CBS6412 cds-NP_012117.3_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005319.1:56136-61175:- gene-YIL149C_CBS6413 rna-NM_001179497.3_CBS6413 cds-NP_012117.3_CBS6413 99.1 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001530.1:54733-59772:- gene-YIL149C_CENPK1137D rna-NM_001179497.3_CENPK1137D cds-NP_012117.3_CENPK1137D 99.1 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005479.1:49782-54821:- gene-YIL149C_EthanolRed rna-NM_001179497.3_EthanolRed cds-NP_012117.3_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005543.1:65585-70624:- gene-YIL149C_FaliES1 rna-NM_001179497.3_FaliES1 cds-NP_012117.3_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000319.1:37731-42770:+ gene-YIL149C_JAY291 rna-NM_001179497.3_JAY291 cds-NP_012117.3_JAY291 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005415.1:64765-69804:- gene-YIL149C_MUCL30387 rna-NM_001179497.3_MUCL30387 cds-NP_012117.3_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005447.1:64013-69052:- gene-YIL149C_MUCL30388 rna-NM_001179497.3_MUCL30388 cds-NP_012117.3_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005287.1:65377-70416:- gene-YIL149C_MUCL39482 rna-NM_001179497.3_MUCL39482 cds-NP_012117.3_MUCL39482 99.1 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005431.1:68578-73617:- gene-YIL149C_MUCL42920 rna-NM_001179497.3_MUCL42920 cds-NP_012117.3_MUCL42920 99.3 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011818.1:63028-68067:- gene-YIL149C_NCIM3186 rna-NM_001179497.3_NCIM3186 cds-NP_012117.3_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005271.1:69342-74381:- gene-YIL149C_NCYC1407 rna-NM_001179497.3_NCYC1407 cds-NP_012117.3_NCYC1407 99.1 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994148.1:63961-69000:- gene-YIL149C_PE2H3 rna-NM_001179497.3_PE2H3 cds-NP_012117.3_PE2H3 99.2 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999880.1:57923-62962:- gene-YIL149C_PE2H4 rna-NM_001179497.3_PE2H4 cds-NP_012117.3_PE2H4 99.2 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001141.2:63028-68067:- gene-YIL149C_S288C rna-NM_001179497.3_S288C cds-NP_012117.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000050.1:41605-46644:- gene-YIL149C_SA1 rna-NM_001179497.3_SA1 cds-NP_012117.3_SA1 99.1 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005495.1:64195-69234:- gene-YIL149C_ThermosaccDry rna-NM_001179497.3_ThermosaccDry cds-NP_012117.3_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005463.1:61347-66386:- gene-YIL149C_VR1 rna-NM_001179497.3_VR1 cds-NP_012117.3_VR1 99.2 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000019.1:39181-44220:- gene-YIL149C_ZTW1 rna-NM_001179497.3_ZTW1 cds-NP_012117.3_ZTW1 99.1 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047495.1:56905-61944:- gene-YIL149C_Sparadoxus rna-NM_001179497.3_Sparadoxus cds-NP_012117.3_Sparadoxus 84.9 99.8 Verified 1 1 1 False True False False False

Additional files