MLP1 (YKR095W)


Gene profile

Gene name: MLP1
Reference locus (S288C): YKR095W
Gene biotype: protein_coding

Description: Nucleoprotein tpr; Myosin-like protein associated with the nuclear envelope; nuclear basket protein that connects the nuclear pore complex with the nuclear interior; involved with Tel1p in telomere length control; involved with Pml1p and Pml39p in nuclear retention of unspliced mRNAs; MLP1 has a paralog, MLP2, that arose from the whole genome duplication

Top 10 interactors (score): MEX67 (0.997); NSP1 (0.996); NUP2 (0.996); MLP2 (0.994); YRA1 (0.993); NUP1 (0.993); NUP60 (0.992); NAB2 (0.985); NIC96 (0.975); GLE2 (0.968); NUP145 (0.955); SEH1 (0.949); SMT3 (0.945); NUP53 (0.942); MAD1 (0.941); NUP133 (0.935); NUP85 (0.935); NUP84 (0.931); SSA1 (0.927); SSA2 (0.927)

Homologues (species, bitscore): TPR (Homo sapiens, 158.3); Tpr (Mus musculus, 166.4); tprb (Danio rerio, 167.5); tpr (Xenopus tropicalis, 164.1); Mtor (Drosophila melanogaster, 63.9); NUA (Arabidopsis thaliana, 85.5)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:605742-611366:+ gene-YKR095W_AKU4011 rna-NM_001179885.1_AKU4011 cds-NP_013021.1_AKU4011 99.6 99.9 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:32773-38400:- gene-YKR095W_BG1 rna-NM_001179885.1_BG1 cds-NP_013021.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:628353-633980:+ gene-YKR095W_Bruggeman rna-NM_001179885.1_Bruggeman cds-NP_013021.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:625638-631265:+ gene-YKR095W_CAT1 rna-NM_001179885.1_CAT1 cds-NP_013021.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:618229-623856:+ gene-YKR095W_CBS1585 rna-NM_001179885.1_CBS1585 cds-NP_013021.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005353.1:616639-622266:+ gene-YKR095W_CBS436 rna-NM_001179885.1_CBS436 cds-NP_013021.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:601518-607145:+ gene-YKR095W_CBS6412 rna-NM_001179885.1_CBS6412 cds-NP_013021.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:618048-623675:+ gene-YKR095W_CBS6413 rna-NM_001179885.1_CBS6413 cds-NP_013021.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:619463-625090:+ gene-YKR095W_CENPK1137D rna-NM_001179885.1_CENPK1137D cds-NP_013021.1_CENPK1137D 99.8 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:615632-621259:+ gene-YKR095W_EthanolRed rna-NM_001179885.1_EthanolRed cds-NP_013021.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:619528-625155:+ gene-YKR095W_FaliES1 rna-NM_001179885.1_FaliES1 cds-NP_013021.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000426.1:19817-25444:- gene-YKR095W_JAY291 rna-NM_001179885.1_JAY291 cds-NP_013021.1_JAY291 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:627870-633497:+ gene-YKR095W_MUCL30387 rna-NM_001179885.1_MUCL30387 cds-NP_013021.1_MUCL30387 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:622180-627807:+ gene-YKR095W_MUCL30388 rna-NM_001179885.1_MUCL30388 cds-NP_013021.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:617070-622694:+ gene-YKR095W_MUCL39482 rna-NM_001179885.1_MUCL39482 cds-NP_013021.1_MUCL39482 99.6 99.9 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:623126-628753:+ gene-YKR095W_MUCL42920 rna-NM_001179885.1_MUCL42920 cds-NP_013021.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:619794-625421:+ gene-YKR095W_NCIM3186 rna-NM_001179885.1_NCIM3186 cds-NP_013021.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:617483-623110:+ gene-YKR095W_NCYC1407 rna-NM_001179885.1_NCYC1407 cds-NP_013021.1_NCYC1407 99.7 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:642731-648358:+ gene-YKR095W_PE2H3 rna-NM_001179885.1_PE2H3 cds-NP_013021.1_PE2H3 99.5 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:627173-632800:+ gene-YKR095W_PE2H4 rna-NM_001179885.1_PE2H4 cds-NP_013021.1_PE2H4 99.4 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:619805-625432:+ gene-YKR095W_S288C rna-NM_001179885.1_S288C cds-NP_013021.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000029.1:56380-62007:- gene-YKR095W_SA1 rna-NM_001179885.1_SA1 cds-NP_013021.1_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:618774-624401:+ gene-YKR095W_ThermosaccDry rna-NM_001179885.1_ThermosaccDry cds-NP_013021.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:618035-623662:+ gene-YKR095W_VR1 rna-NM_001179885.1_VR1 cds-NP_013021.1_VR1 99.5 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:615741-621368:+ gene-YKR095W_ZTW1 rna-NM_001179885.1_ZTW1 cds-NP_013021.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:641093-646722:+ gene-YKR095W_Sparadoxus rna-NM_001179885.1_Sparadoxus cds-NP_013021.1_Sparadoxus 86.1 99.9 Verified 1 1 0 False False False True False

Additional files