Gene name: MLH2
Reference locus (S288C): YLR035C
Gene biotype: protein_coding
Description: Protein involved in mismatch repair and meiotic recombination; only certain frameshift intermediates are mismatch repair substrates; forms a complex with Mlh1p
Top 10 interactors (score): MSH4 (0.969); MSH5 (0.961); MLH1 (0.94); MSH6 (0.939); MSH3 (0.936); MSH2 (0.923); SPO22 (0.843); MSH1 (0.823); SPO74 (0.812); MUS81 (0.809); DON1 (0.749); SPO16 (0.747); REC104 (0.744); HFM1 (0.738); MND1 (0.73); ZIP2 (0.718); EXO1 (0.703); RAD51 (0.696); SPO21 (0.694); RAD10 (0.68)
Homologues (species, bitscore): PMS1 (Homo sapiens, 103.6); Pms1 (Mus musculus, 104.8); pms2 (Danio rerio, 99.8); pms1 (Xenopus tropicalis, 109.4); Pms2 (Drosophila melanogaster, 104.8); pms-2 (Caenorhabditis elegans, 103.6); PMS1 (Arabidopsis thaliana, 109.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:200304-202391:- | gene-YLR035C_AKU4011 | rna-NM_001181922.1_AKU4011 | cds-NP_013135.1_AKU4011 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000212.1:163585-165672:- | gene-YLR035C_BG1 | rna-NM_001181922.1_BG1 | cds-NP_013135.1_BG1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:210696-212783:- | gene-YLR035C_Bruggeman | rna-NM_001181922.1_Bruggeman | cds-NP_013135.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:211022-213109:- | gene-YLR035C_CAT1 | rna-NM_001181922.1_CAT1 | cds-NP_013135.1_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:207930-210017:- | gene-YLR035C_CBS1585 | rna-NM_001181922.1_CBS1585 | cds-NP_013135.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:198560-200647:- | gene-YLR035C_CBS436 | rna-NM_001181922.1_CBS436 | cds-NP_013135.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:206340-208427:- | gene-YLR035C_CBS6412 | rna-NM_001181922.1_CBS6412 | cds-NP_013135.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:208191-210278:- | gene-YLR035C_CBS6413 | rna-NM_001181922.1_CBS6413 | cds-NP_013135.1_CBS6413 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:197602-199689:- | gene-YLR035C_CENPK1137D | rna-NM_001181922.1_CENPK1137D | cds-NP_013135.1_CENPK1137D | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:200316-202403:- | gene-YLR035C_EthanolRed | rna-NM_001181922.1_EthanolRed | cds-NP_013135.1_EthanolRed | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:200224-202311:- | gene-YLR035C_FaliES1 | rna-NM_001181922.1_FaliES1 | cds-NP_013135.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000431.1:44079-46166:- | gene-YLR035C_JAY291 | rna-NM_001181922.1_JAY291 | cds-NP_013135.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:208049-210136:- | gene-YLR035C_MUCL30387 | rna-NM_001181922.1_MUCL30387 | cds-NP_013135.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:215052-217139:- | gene-YLR035C_MUCL30388 | rna-NM_001181922.1_MUCL30388 | cds-NP_013135.1_MUCL30388 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:208425-210512:- | gene-YLR035C_MUCL39482 | rna-NM_001181922.1_MUCL39482 | cds-NP_013135.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:208328-210415:- | gene-YLR035C_MUCL42920 | rna-NM_001181922.1_MUCL42920 | cds-NP_013135.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:212343-214430:- | gene-YLR035C_NCIM3186 | rna-NM_001181922.1_NCIM3186 | cds-NP_013135.1_NCIM3186 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:200484-202571:- | gene-YLR035C_NCYC1407 | rna-NM_001181922.1_NCYC1407 | cds-NP_013135.1_NCYC1407 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:206358-208445:- | gene-YLR035C_PE2H3 | rna-NM_001181922.1_PE2H3 | cds-NP_013135.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:206099-208186:- | gene-YLR035C_PE2H4 | rna-NM_001181922.1_PE2H4 | cds-NP_013135.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:212369-214456:- | gene-YLR035C_S288C | rna-NM_001181922.1_S288C | cds-NP_013135.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000046.1:44207-46294:- | gene-YLR035C_SA1 | rna-NM_001181922.1_SA1 | cds-NP_013135.1_SA1 | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:200390-202477:- | gene-YLR035C_ThermosaccDry | rna-NM_001181922.1_ThermosaccDry | cds-NP_013135.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:213808-215895:- | gene-YLR035C_VR1 | rna-NM_001181922.1_VR1 | cds-NP_013135.1_VR1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000023.1:199756-201843:- | gene-YLR035C_ZTW1 | rna-NM_001181922.1_ZTW1 | cds-NP_013135.1_ZTW1 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:208537-210621:- | gene-YLR035C_Sparadoxus | rna-NM_001181922.1_Sparadoxus | cds-NP_013135.1_Sparadoxus | 87.8 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |