Gene name: MLC2
Reference locus (S288C): YPR188C
Gene biotype: protein_coding
Description: Regulatory light chain for the type II myosin Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring
Top 10 interactors (score): MYO1 (0.998); MLC1 (0.986); CCH1 (0.975); IQG1 (0.958); STE20 (0.914); SKM1 (0.914); CLA4 (0.914); ACT1 (0.907); MYO2 (0.878); HOF1 (0.797); TPM2 (0.777); CDC42 (0.775); CYK3 (0.749); YOR114W (0.748); TPM1 (0.738); CHS2 (0.731); TUB2 (0.719); OLE1 (0.703); BNR1 (0.674); PPT1 (0.671)
Homologues (species, bitscore): CALM2 (Homo sapiens, 54.7); Calm3 (Mus musculus, 54.7); Calm2b (Danio rerio, 54.7); Calm1 (Xenopus tropicalis, 54.7); Cam (Drosophila melanogaster, 53.1); cmd-1 (Caenorhabditis elegans, 53.5); CAM9 (Arabidopsis thaliana, 60.5)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005310.1:866272-866763:- | gene-YPR188C_AKU4011 | rna-NM_001184285.1_AKU4011 | cds-NP_015514.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000091.1:30958-31449:+ | gene-YPR188C_BG1 | rna-NM_001184285.1_BG1 | cds-NP_015514.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:947547-948038:- | gene-YPR188C_Bruggeman | rna-NM_001184285.1_Bruggeman | cds-NP_015514.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005534.1:989603-990094:- | gene-YPR188C_CAT1 | rna-NM_001184285.1_CAT1 | cds-NP_015514.1_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005374.1:871073-871564:- | gene-YPR188C_CBS1585 | rna-NM_001184285.1_CBS1585 | cds-NP_015514.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005358.1:884611-885102:- | gene-YPR188C_CBS436 | rna-NM_001184285.1_CBS436 | cds-NP_015514.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005342.1:872856-873347:- | gene-YPR188C_CBS6412 | rna-NM_001184285.1_CBS6412 | cds-NP_015514.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005326.1:868001-868492:- | gene-YPR188C_CBS6413 | rna-NM_001184285.1_CBS6413 | cds-NP_015514.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001537.1:912063-912554:- | gene-YPR188C_CENPK1137D | rna-NM_001184285.1_CENPK1137D | cds-NP_015514.1_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005486.1:1188025-1188516:- | gene-YPR188C_EthanolRed | rna-NM_001184285.1_EthanolRed | cds-NP_015514.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005550.1:868098-868589:- | gene-YPR188C_FaliES1 | rna-NM_001184285.1_FaliES1 | cds-NP_015514.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000081.1:55390-55881:- | gene-YPR188C_JAY291 | rna-NM_001184285.1_JAY291 | cds-NP_015514.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005422.1:914777-915268:- | gene-YPR188C_MUCL30387 | rna-NM_001184285.1_MUCL30387 | cds-NP_015514.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005454.1:888909-889400:- | gene-YPR188C_MUCL30388 | rna-NM_001184285.1_MUCL30388 | cds-NP_015514.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005294.1:863274-863765:- | gene-YPR188C_MUCL39482 | rna-NM_001184285.1_MUCL39482 | cds-NP_015514.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005438.1:927735-928226:- | gene-YPR188C_MUCL42920 | rna-NM_001184285.1_MUCL42920 | cds-NP_015514.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011825.1:911971-912462:- | gene-YPR188C_NCIM3186 | rna-NM_001184285.1_NCIM3186 | cds-NP_015514.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005278.1:871635-872126:- | gene-YPR188C_NCYC1407 | rna-NM_001184285.1_NCYC1407 | cds-NP_015514.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994155.1:883918-884409:- | gene-YPR188C_PE2H3 | rna-NM_001184285.1_PE2H3 | cds-NP_015514.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999887.1:883566-884057:- | gene-YPR188C_PE2H4 | rna-NM_001184285.1_PE2H4 | cds-NP_015514.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001148.4:911988-912479:- | gene-YPR188C_S288C | rna-NM_001184285.1_S288C | cds-NP_015514.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000060.1:13332-13823:+ | gene-YPR188C_SA1 | rna-NM_001184285.1_SA1 | cds-NP_015514.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005502.1:867786-868277:- | gene-YPR188C_ThermosaccDry | rna-NM_001184285.1_ThermosaccDry | cds-NP_015514.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005470.1:895571-896062:- | gene-YPR188C_VR1 | rna-NM_001184285.1_VR1 | cds-NP_015514.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000033.1:870331-870822:- | gene-YPR188C_ZTW1 | rna-NM_001184285.1_ZTW1 | cds-NP_015514.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047502.1:872364-872855:- | gene-YPR188C_Sparadoxus | rna-NM_001184285.1_Sparadoxus | cds-NP_015514.1_Sparadoxus | 91.6 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |