Gene name: MLC1
Reference locus (S288C): YGL106W
Gene biotype: protein_coding
Description: Essential light chain for Myo1p; light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition
Top 10 interactors (score): MYO1 (0.999); MYO2 (0.999); IQG1 (0.999); MLC2 (0.986); MYO4 (0.984); CCH1 (0.975); HOF1 (0.963); SHE3 (0.956); ACT1 (0.953); STE20 (0.936); CLA4 (0.914); SKM1 (0.914); CYK3 (0.894); PIK1 (0.892); EXO70 (0.883); SEC4 (0.882); BNI1 (0.881); CDC42 (0.869); CMD1 (0.856); SPA2 (0.846)
Homologues (species, bitscore): CALM2 (Homo sapiens, 98.6); Calm3 (Mus musculus, 98.6); Calm2b (Danio rerio, 98.6); Calm1 (Xenopus tropicalis, 98.6); Cam (Drosophila melanogaster, 97.4); cmd-1 (Caenorhabditis elegans, 97.4); CAM5 (Arabidopsis thaliana, 102.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:309886-310335:+ | gene-YGL106W_AKU4011 | rna-NM_001180971.1_AKU4011 | cds-NP_011409.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:95411-95860:- | gene-YGL106W_BG1 | rna-NM_001180971.1_BG1 | cds-NP_011409.1_BG1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:312045-312494:+ | gene-YGL106W_Bruggeman | rna-NM_001180971.1_Bruggeman | cds-NP_011409.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:307567-308016:+ | gene-YGL106W_CAT1 | rna-NM_001180971.1_CAT1 | cds-NP_011409.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:313212-313661:+ | gene-YGL106W_CBS1585 | rna-NM_001180971.1_CBS1585 | cds-NP_011409.1_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:307515-307964:+ | gene-YGL106W_CBS436 | rna-NM_001180971.1_CBS436 | cds-NP_011409.1_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:297905-298354:+ | gene-YGL106W_CBS6412 | rna-NM_001180971.1_CBS6412 | cds-NP_011409.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:307510-307959:+ | gene-YGL106W_CBS6413 | rna-NM_001180971.1_CBS6413 | cds-NP_011409.1_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:306747-307196:+ | gene-YGL106W_CENPK1137D | rna-NM_001180971.1_CENPK1137D | cds-NP_011409.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:298959-299408:+ | gene-YGL106W_EthanolRed | rna-NM_001180971.1_EthanolRed | cds-NP_011409.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:301514-301963:+ | gene-YGL106W_FaliES1 | rna-NM_001180971.1_FaliES1 | cds-NP_011409.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000046.1:183-632:- | gene-YGL106W_JAY291 | rna-NM_001180971.1_JAY291 | cds-NP_011409.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:309015-309464:+ | gene-YGL106W_MUCL30387 | rna-NM_001180971.1_MUCL30387 | cds-NP_011409.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:312106-312555:+ | gene-YGL106W_MUCL30388 | rna-NM_001180971.1_MUCL30388 | cds-NP_011409.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:309725-310174:+ | gene-YGL106W_MUCL39482 | rna-NM_001180971.1_MUCL39482 | cds-NP_011409.1_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:313004-313453:+ | gene-YGL106W_MUCL42920 | rna-NM_001180971.1_MUCL42920 | cds-NP_011409.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:306560-307009:+ | gene-YGL106W_NCIM3186 | rna-NM_001180971.1_NCIM3186 | cds-NP_011409.1_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:301215-301664:+ | gene-YGL106W_NCYC1407 | rna-NM_001180971.1_NCYC1407 | cds-NP_011409.1_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:302599-303048:+ | gene-YGL106W_PE2H3 | rna-NM_001180971.1_PE2H3 | cds-NP_011409.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:307597-308046:+ | gene-YGL106W_PE2H4 | rna-NM_001180971.1_PE2H4 | cds-NP_011409.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:306560-307009:+ | gene-YGL106W_S288C | rna-NM_001180971.1_S288C | cds-NP_011409.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000064.1:51347-51796:+ | gene-YGL106W_SA1 | rna-NM_001180971.1_SA1 | cds-NP_011409.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:301726-302175:+ | gene-YGL106W_ThermosaccDry | rna-NM_001180971.1_ThermosaccDry | cds-NP_011409.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:411322-411771:+ | gene-YGL106W_VR1 | rna-NM_001180971.1_VR1 | cds-NP_011409.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:299123-299572:+ | gene-YGL106W_ZTW1 | rna-NM_001180971.1_ZTW1 | cds-NP_011409.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:305549-305998:+ | gene-YGL106W_Sparadoxus | rna-NM_001180971.1_Sparadoxus | cds-NP_011409.1_Sparadoxus | 90.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |