MKS1 (YNL076W)


Gene profile

Gene name: MKS1
Reference locus (S288C): YNL076W
Gene biotype: protein_coding

Description: Pleiotropic negative transcriptional regulator; involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling

Top 10 interactors (score): RTG2 (0.996); BMH1 (0.987); RTG1 (0.955); RTG3 (0.95); YGR054W (0.903); LST8 (0.84); BMH2 (0.818); GRR1 (0.817); TOR1 (0.799); URE2 (0.776); GLN3 (0.756); TAP42 (0.726); CIT2 (0.713); KOG1 (0.666); GLN1 (0.635); TOR2 (0.633); PPA2 (0.617); TPS1 (0.584); SIT4 (0.564); RAS2 (0.525)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005308.1:477225-478979:+ gene-YNL076W_AKU4011 rna-NM_001182914.1_AKU4011 cds-NP_014323.1_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000155.1:381253-383007:+ gene-YNL076W_BG1 rna-NM_001182914.1_BG1 cds-NP_014323.1_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005516.1:487954-489708:+ gene-YNL076W_Bruggeman rna-NM_001182914.1_Bruggeman cds-NP_014323.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005532.1:530949-532703:+ gene-YNL076W_CAT1 rna-NM_001182914.1_CAT1 cds-NP_014323.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005372.1:477893-479647:+ gene-YNL076W_CBS1585 rna-NM_001182914.1_CBS1585 cds-NP_014323.1_CBS1585 99.3 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:546308-548062:+ gene-YNL076W_CBS436 rna-NM_001182914.1_CBS436 cds-NP_014323.1_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005340.1:472987-474741:+ gene-YNL076W_CBS6412 rna-NM_001182914.1_CBS6412 cds-NP_014323.1_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005324.1:474304-476058:+ gene-YNL076W_CBS6413 rna-NM_001182914.1_CBS6413 cds-NP_014323.1_CBS6413 99.2 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001535.1:477414-479168:+ gene-YNL076W_CENPK1137D rna-NM_001182914.1_CENPK1137D cds-NP_014323.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005484.1:480047-481801:+ gene-YNL076W_EthanolRed rna-NM_001182914.1_EthanolRed cds-NP_014323.1_EthanolRed 99.2 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005548.1:470571-472325:+ gene-YNL076W_FaliES1 rna-NM_001182914.1_FaliES1 cds-NP_014323.1_FaliES1 99.2 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000317.1:1269-3023:- gene-YNL076W_JAY291 rna-NM_001182914.1_JAY291 cds-NP_014323.1_JAY291 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005420.1:484117-485871:+ gene-YNL076W_MUCL30387 rna-NM_001182914.1_MUCL30387 cds-NP_014323.1_MUCL30387 99.3 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005452.1:519515-521269:+ gene-YNL076W_MUCL30388 rna-NM_001182914.1_MUCL30388 cds-NP_014323.1_MUCL30388 99.3 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005292.1:475296-477050:+ gene-YNL076W_MUCL39482 rna-NM_001182914.1_MUCL39482 cds-NP_014323.1_MUCL39482 99.3 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005436.1:479225-480979:+ gene-YNL076W_MUCL42920 rna-NM_001182914.1_MUCL42920 cds-NP_014323.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011823.1:483525-485279:+ gene-YNL076W_NCIM3186 rna-NM_001182914.1_NCIM3186 cds-NP_014323.1_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005276.1:477346-479100:+ gene-YNL076W_NCYC1407 rna-NM_001182914.1_NCYC1407 cds-NP_014323.1_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994153.1:480582-482336:+ gene-YNL076W_PE2H3 rna-NM_001182914.1_PE2H3 cds-NP_014323.1_PE2H3 99.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999885.1:475657-477411:+ gene-YNL076W_PE2H4 rna-NM_001182914.1_PE2H4 cds-NP_014323.1_PE2H4 99.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001146.8:483556-485310:+ gene-YNL076W_S288C rna-NM_001182914.1_S288C cds-NP_014323.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000024.1:68510-70264:+ gene-YNL076W_SA1 rna-NM_001182914.1_SA1 cds-NP_014323.1_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005500.1:471447-473201:+ gene-YNL076W_ThermosaccDry rna-NM_001182914.1_ThermosaccDry cds-NP_014323.1_ThermosaccDry 99.2 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005468.1:490565-492319:+ gene-YNL076W_VR1 rna-NM_001182914.1_VR1 cds-NP_014323.1_VR1 99.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000030.1:380797-382551:+ gene-YNL076W_ZTW1 rna-NM_001182914.1_ZTW1 cds-NP_014323.1_ZTW1 99.2 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047500.1:486998-488755:+ gene-YNL076W_Sparadoxus rna-NM_001182914.1_Sparadoxus cds-NP_014323.1_Sparadoxus 90.6 100.0 Verified 1 1 1 False True False False False

Additional files