Gene name: MKK1
Reference locus (S288C): YOR231W
Gene biotype: protein_coding
Description: MAPKK involved in the protein kinase C signaling pathway; involved in control of cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p; MKK1 has a paralog, MKK2, that arose from the whole genome duplication
Top 10 interactors (score): BCK1 (0.999); SLT2 (0.998); RHO1 (0.984); STE11 (0.98); MKK2 (0.978); KDX1 (0.977); SPA2 (0.977); HOG1 (0.971); SMK1 (0.96); SLG1 (0.947); PTC1 (0.93); RLM1 (0.925); MSS4 (0.908); MID2 (0.887); ROM2 (0.874); KSS1 (0.873); FUS3 (0.87); MSG5 (0.869); RHO2 (0.857); PTP2 (0.856)
Homologues (species, bitscore): MAP2K5 (Homo sapiens, 216.1); Map2k5 (Mus musculus, 218.4); map2k5 (Danio rerio, 212.2); map2k1 (Xenopus tropicalis, 209.9); Dsor1 (Drosophila melanogaster, 227.3); mek-2 (Caenorhabditis elegans, 194.1); MEK1 (Arabidopsis thaliana, 194.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:763373-764899:+ | gene-YOR231W_AKU4011 | rna-NM_001183650.1_AKU4011 | cds-NP_014874.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:165413-166939:+ | gene-YOR231W_BG1 | rna-NM_001183650.1_BG1 | cds-NP_014874.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:748840-750366:+ | gene-YOR231W_Bruggeman | rna-NM_001183650.1_Bruggeman | cds-NP_014874.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:749491-751017:+ | gene-YOR231W_CAT1 | rna-NM_001183650.1_CAT1 | cds-NP_014874.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:746362-747888:+ | gene-YOR231W_CBS1585 | rna-NM_001183650.1_CBS1585 | cds-NP_014874.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:745057-746583:+ | gene-YOR231W_CBS436 | rna-NM_001183650.1_CBS436 | cds-NP_014874.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:743481-745007:+ | gene-YOR231W_CBS6412 | rna-NM_001183650.1_CBS6412 | cds-NP_014874.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:752121-753647:+ | gene-YOR231W_CBS6413 | rna-NM_001183650.1_CBS6413 | cds-NP_014874.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:772363-773889:+ | gene-YOR231W_CENPK1137D | rna-NM_001183650.1_CENPK1137D | cds-NP_014874.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:739493-741019:+ | gene-YOR231W_EthanolRed | rna-NM_001183650.1_EthanolRed | cds-NP_014874.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:744892-746418:+ | gene-YOR231W_FaliES1 | rna-NM_001183650.1_FaliES1 | cds-NP_014874.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:80419-81945:- | gene-YOR231W_JAY291 | rna-NM_001183650.1_JAY291 | cds-NP_014874.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:752163-753689:+ | gene-YOR231W_MUCL30387 | rna-NM_001183650.1_MUCL30387 | cds-NP_014874.1_MUCL30387 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:760229-761755:+ | gene-YOR231W_MUCL30388 | rna-NM_001183650.1_MUCL30388 | cds-NP_014874.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:753692-755218:+ | gene-YOR231W_MUCL39482 | rna-NM_001183650.1_MUCL39482 | cds-NP_014874.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:763281-764807:+ | gene-YOR231W_MUCL42920 | rna-NM_001183650.1_MUCL42920 | cds-NP_014874.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:772490-774016:+ | gene-YOR231W_NCIM3186 | rna-NM_001183650.1_NCIM3186 | cds-NP_014874.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:753791-755317:+ | gene-YOR231W_NCYC1407 | rna-NM_001183650.1_NCYC1407 | cds-NP_014874.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:753093-754619:+ | gene-YOR231W_PE2H3 | rna-NM_001183650.1_PE2H3 | cds-NP_014874.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:763470-764996:+ | gene-YOR231W_PE2H4 | rna-NM_001183650.1_PE2H4 | cds-NP_014874.1_PE2H4 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:772601-774127:+ | gene-YOR231W_S288C | rna-NM_001183650.1_S288C | cds-NP_014874.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:182594-184120:+ | gene-YOR231W_SA1 | rna-NM_001183650.1_SA1 | cds-NP_014874.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:744075-745601:+ | gene-YOR231W_ThermosaccDry | rna-NM_001183650.1_ThermosaccDry | cds-NP_014874.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:807533-809059:+ | gene-YOR231W_VR1 | rna-NM_001183650.1_VR1 | cds-NP_014874.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:476996-478522:+ | gene-YOR231W_ZTW1 | rna-NM_001183650.1_ZTW1 | cds-NP_014874.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:749954-751477:+ | gene-YOR231W_Sparadoxus | rna-NM_001183650.1_Sparadoxus | cds-NP_014874.1_Sparadoxus | 90.0 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |