Gene name: MKC7
Reference locus (S288C): YDR144C
Gene biotype: protein_coding
Description: Aspartic proteinase MKC7; GPI-anchored aspartyl protease; member of the yapsin family of proteases involved in cell wall growth and maintenance; shares functions with Yap3p and Kex2p; MKC7 has a paralog, YPS1, that arose from the whole genome duplication
Top 10 interactors (score): YPS1 (0.955); MSB2 (0.932); KEX2 (0.914); PRB1 (0.766); PRC1 (0.751); DDI1 (0.749); KEX1 (0.749); YML108W (0.716); IRC22 (0.703); UTR2 (0.608); YIL082W-A (0.572); STE24 (0.57); YPS7 (0.569); YGR109W-B (0.529); RRT12 (0.512); UFO1 (0.502); GAS1 (0.501); PLB3 (0.5); RCE1 (0.483); YGL114W (0.453)
Homologues (species, bitscore): PGC (Homo sapiens, 105.9); Pgc (Mus musculus, 98.2); NAPSA (Danio rerio, 100.9); ENSXETP00000003012 (Xenopus tropicalis, 102.8); CG17283 (Drosophila melanogaster, 93.6); asp-1 (Caenorhabditis elegans, 79.7); AT1G62290 (Arabidopsis thaliana, 69.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:715246-717036:- | gene-YDR144C_AKU4011 | rna-NM_001180451.3_AKU4011 | cds-NP_010428.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:407796-409586:+ | gene-YDR144C_BG1 | rna-NM_001180451.3_BG1 | cds-NP_010428.3_BG1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:747302-749092:- | gene-YDR144C_Bruggeman | rna-NM_001180451.3_Bruggeman | cds-NP_010428.3_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:735274-737064:- | gene-YDR144C_CAT1 | rna-NM_001180451.3_CAT1 | cds-NP_010428.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:706284-708074:- | gene-YDR144C_CBS1585 | rna-NM_001180451.3_CBS1585 | cds-NP_010428.3_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:732194-733984:- | gene-YDR144C_CBS436 | rna-NM_001180451.3_CBS436 | cds-NP_010428.3_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:702636-704426:- | gene-YDR144C_CBS6412 | rna-NM_001180451.3_CBS6412 | cds-NP_010428.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:731611-733401:- | gene-YDR144C_CBS6413 | rna-NM_001180451.3_CBS6413 | cds-NP_010428.3_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:736749-738539:- | gene-YDR144C_CENPK1137D | rna-NM_001180451.3_CENPK1137D | cds-NP_010428.3_CENPK1137D | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:717008-718798:- | gene-YDR144C_EthanolRed | rna-NM_001180451.3_EthanolRed | cds-NP_010428.3_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:723802-725592:- | gene-YDR144C_FaliES1 | rna-NM_001180451.3_FaliES1 | cds-NP_010428.3_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000002.1:75942-77732:- | gene-YDR144C_JAY291 | rna-NM_001180451.3_JAY291 | cds-NP_010428.3_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:733226-735016:- | gene-YDR144C_MUCL30387 | rna-NM_001180451.3_MUCL30387 | cds-NP_010428.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:722245-724035:- | gene-YDR144C_MUCL30388 | rna-NM_001180451.3_MUCL30388 | cds-NP_010428.3_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:707626-709416:- | gene-YDR144C_MUCL39482 | rna-NM_001180451.3_MUCL39482 | cds-NP_010428.3_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:645583-647373:- | gene-YDR144C_MUCL42920 | rna-NM_001180451.3_MUCL42920 | cds-NP_010428.3_MUCL42920 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:744234-746024:- | gene-YDR144C_NCIM3186 | rna-NM_001180451.3_NCIM3186 | cds-NP_010428.3_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:707028-708818:- | gene-YDR144C_NCYC1407 | rna-NM_001180451.3_NCYC1407 | cds-NP_010428.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:726366-728156:- | gene-YDR144C_PE2H3 | rna-NM_001180451.3_PE2H3 | cds-NP_010428.3_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:725671-727461:- | gene-YDR144C_PE2H4 | rna-NM_001180451.3_PE2H4 | cds-NP_010428.3_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:744311-746101:- | gene-YDR144C_S288C | rna-NM_001180451.3_S288C | cds-NP_010428.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000009.1:92982-94772:- | gene-YDR144C_SA1 | rna-NM_001180451.3_SA1 | cds-NP_010428.3_SA1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:723324-725114:- | gene-YDR144C_ThermosaccDry | rna-NM_001180451.3_ThermosaccDry | cds-NP_010428.3_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:736693-738483:- | gene-YDR144C_VR1 | rna-NM_001180451.3_VR1 | cds-NP_010428.3_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:720907-722697:- | gene-YDR144C_ZTW1 | rna-NM_001180451.3_ZTW1 | cds-NP_010428.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:725444-727234:- | gene-YDR144C_Sparadoxus | rna-NM_001180451.3_Sparadoxus | cds-NP_010428.3_Sparadoxus | 87.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |