Gene name: MIG3
Reference locus (S288C): YER028C
Gene biotype: protein_coding
Description: Transcription corepressor MIG3; Transcriptional regulator; partially nonfunctional in S288C strains but has a major role in catabolite repression and ethanol response in some other strains; involved in response to toxic agents; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genesenvironment; Belongs to the creA/MIG C2H2-type zinc-finger protein family
Top 10 interactors (score): APT2 (0.695); RGT1 (0.65); GAT4 (0.604); SNF1 (0.594); YHR177W (0.574); YMR279C (0.499); CUE5 (0.488); CYC8 (0.481); ECI1 (0.477); HOL1 (0.459); AQR1 (0.458); NAT3 (0.456); RPO21 (0.442); GCN4 (0.441); STH1 (0.426); SNF2 (0.426); IXR1 (0.42); SPT7 (0.414); HAT2 (0.414); GCN5 (0.414)
Homologues (species, bitscore): EGR1 (Homo sapiens, 72.4); Egr1 (Mus musculus, 72.8); zgc:175128 (Danio rerio, 73.6); klf7 (Xenopus tropicalis, 72.8); sr (Drosophila melanogaster, 72.8); blmp-1 (Caenorhabditis elegans, 68.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:204719-205903:- | gene-YER028C_AKU4011 | rna-NM_001178919.1_AKU4011 | cds-NP_010945.1_AKU4011 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:219838-221022:+ | gene-YER028C_BG1 | rna-NM_001178919.1_BG1 | cds-NP_010945.1_BG1 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:213610-214795:- | gene-YER028C_Bruggeman | rna-NM_001178919.1_Bruggeman | cds-NP_010945.1_Bruggeman | 98.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:207722-208905:- | gene-YER028C_CAT1 | rna-NM_001178919.1_CAT1 | cds-NP_010945.1_CAT1 | 99.2 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:204642-205826:- | gene-YER028C_CBS1585 | rna-NM_001178919.1_CBS1585 | cds-NP_010945.1_CBS1585 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:206575-207759:- | gene-YER028C_CBS436 | rna-NM_001178919.1_CBS436 | cds-NP_010945.1_CBS436 | 98.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:204886-206070:- | gene-YER028C_CBS6412 | rna-NM_001178919.1_CBS6412 | cds-NP_010945.1_CBS6412 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:210152-211336:- | gene-YER028C_CBS6413 | rna-NM_001178919.1_CBS6413 | cds-NP_010945.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:208631-209815:- | gene-YER028C_CENPK1137D | rna-NM_001178919.1_CENPK1137D | cds-NP_010945.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:205351-206535:- | gene-YER028C_EthanolRed | rna-NM_001178919.1_EthanolRed | cds-NP_010945.1_EthanolRed | 99.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:205616-206800:- | gene-YER028C_FaliES1 | rna-NM_001178919.1_FaliES1 | cds-NP_010945.1_FaliES1 | 99.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000192.1:3375-4559:- | gene-YER028C_JAY291 | rna-NM_001178919.1_JAY291 | cds-NP_010945.1_JAY291 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:209043-210228:- | gene-YER028C_MUCL30387 | rna-NM_001178919.1_MUCL30387 | cds-NP_010945.1_MUCL30387 | 98.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:205274-206459:- | gene-YER028C_MUCL30388 | rna-NM_001178919.1_MUCL30388 | cds-NP_010945.1_MUCL30388 | 98.3 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:203686-204870:- | gene-YER028C_MUCL39482 | rna-NM_001178919.1_MUCL39482 | cds-NP_010945.1_MUCL39482 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:210772-211957:- | gene-YER028C_MUCL42920 | rna-NM_001178919.1_MUCL42920 | cds-NP_010945.1_MUCL42920 | 98.4 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:210691-211875:- | gene-YER028C_NCIM3186 | rna-NM_001178919.1_NCIM3186 | cds-NP_010945.1_NCIM3186 | 98.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:208757-209941:- | gene-YER028C_NCYC1407 | rna-NM_001178919.1_NCYC1407 | cds-NP_010945.1_NCYC1407 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:219383-220567:- | gene-YER028C_PE2H3 | rna-NM_001178919.1_PE2H3 | cds-NP_010945.1_PE2H3 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:209323-210507:- | gene-YER028C_PE2H4 | rna-NM_001178919.1_PE2H4 | cds-NP_010945.1_PE2H4 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:210692-211876:- | gene-YER028C_S288C | rna-NM_001178919.1_S288C | cds-NP_010945.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000020.1:31808-32991:+ | gene-YER028C_SA1 | rna-NM_001178919.1_SA1 | cds-NP_010945.1_SA1 | 99.8 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:206387-207571:- | gene-YER028C_ThermosaccDry | rna-NM_001178919.1_ThermosaccDry | cds-NP_010945.1_ThermosaccDry | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | False | True |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:205479-206663:- | gene-YER028C_VR1 | rna-NM_001178919.1_VR1 | cds-NP_010945.1_VR1 | 98.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:203599-204783:- | gene-YER028C_ZTW1 | rna-NM_001178919.1_ZTW1 | cds-NP_010945.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:207472-208663:- | gene-YER028C_Sparadoxus | rna-NM_001178919.1_Sparadoxus | cds-NP_010945.1_Sparadoxus | 83.2 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |