MIG3 (YER028C)


Gene profile

Gene name: MIG3
Reference locus (S288C): YER028C
Gene biotype: protein_coding

Description: Transcription corepressor MIG3; Transcriptional regulator; partially nonfunctional in S288C strains but has a major role in catabolite repression and ethanol response in some other strains; involved in response to toxic agents; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genesenvironment; Belongs to the creA/MIG C2H2-type zinc-finger protein family

Top 10 interactors (score): APT2 (0.695); RGT1 (0.65); GAT4 (0.604); SNF1 (0.594); YHR177W (0.574); YMR279C (0.499); CUE5 (0.488); CYC8 (0.481); ECI1 (0.477); HOL1 (0.459); AQR1 (0.458); NAT3 (0.456); RPO21 (0.442); GCN4 (0.441); STH1 (0.426); SNF2 (0.426); IXR1 (0.42); SPT7 (0.414); HAT2 (0.414); GCN5 (0.414)

Homologues (species, bitscore): EGR1 (Homo sapiens, 72.4); Egr1 (Mus musculus, 72.8); zgc:175128 (Danio rerio, 73.6); klf7 (Xenopus tropicalis, 72.8); sr (Drosophila melanogaster, 72.8); blmp-1 (Caenorhabditis elegans, 68.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005299.1:204719-205903:- gene-YER028C_AKU4011 rna-NM_001178919.1_AKU4011 cds-NP_010945.1_AKU4011 99.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000011.1:219838-221022:+ gene-YER028C_BG1 rna-NM_001178919.1_BG1 cds-NP_010945.1_BG1 98.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005507.1:213610-214795:- gene-YER028C_Bruggeman rna-NM_001178919.1_Bruggeman cds-NP_010945.1_Bruggeman 98.3 100.0 Unannotated 1 1 0 False False False True False
CAT1 GCA_001738705.1 Bioethanol South America CM005523.1:207722-208905:- gene-YER028C_CAT1 rna-NM_001178919.1_CAT1 cds-NP_010945.1_CAT1 99.2 99.9 Unannotated 1 1 0 False False False True False
CBS1585 GCA_001738375.1 Sake Asia CM005363.1:204642-205826:- gene-YER028C_CBS1585 rna-NM_001178919.1_CBS1585 cds-NP_010945.1_CBS1585 99.9 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005347.1:206575-207759:- gene-YER028C_CBS436 rna-NM_001178919.1_CBS436 cds-NP_010945.1_CBS436 98.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005331.1:204886-206070:- gene-YER028C_CBS6412 rna-NM_001178919.1_CBS6412 cds-NP_010945.1_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005315.1:210152-211336:- gene-YER028C_CBS6413 rna-NM_001178919.1_CBS6413 cds-NP_010945.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001526.1:208631-209815:- gene-YER028C_CENPK1137D rna-NM_001178919.1_CENPK1137D cds-NP_010945.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005475.1:205351-206535:- gene-YER028C_EthanolRed rna-NM_001178919.1_EthanolRed cds-NP_010945.1_EthanolRed 99.9 100.0 Unannotated 1 1 0 False False False False True
FaliES1 GCA_001738715.1 Bioethanol Asia CM005539.1:205616-206800:- gene-YER028C_FaliES1 rna-NM_001178919.1_FaliES1 cds-NP_010945.1_FaliES1 99.9 100.0 Unannotated 1 1 0 False False False False True
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000192.1:3375-4559:- gene-YER028C_JAY291 rna-NM_001178919.1_JAY291 cds-NP_010945.1_JAY291 98.3 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005411.1:209043-210228:- gene-YER028C_MUCL30387 rna-NM_001178919.1_MUCL30387 cds-NP_010945.1_MUCL30387 98.2 100.0 Unannotated 1 1 0 False False False True False
MUCL30388 GCA_001738495.1 Bread Europe CM005443.1:205274-206459:- gene-YER028C_MUCL30388 rna-NM_001178919.1_MUCL30388 cds-NP_010945.1_MUCL30388 98.3 100.0 Unannotated 1 1 0 False False False True False
MUCL39482 GCA_001738235.1 Sake Asia CM005283.1:203686-204870:- gene-YER028C_MUCL39482 rna-NM_001178919.1_MUCL39482 cds-NP_010945.1_MUCL39482 99.9 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005427.1:210772-211957:- gene-YER028C_MUCL42920 rna-NM_001178919.1_MUCL42920 cds-NP_010945.1_MUCL42920 98.4 100.0 Unannotated 1 1 0 False False False True False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011814.1:210691-211875:- gene-YER028C_NCIM3186 rna-NM_001178919.1_NCIM3186 cds-NP_010945.1_NCIM3186 98.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005267.1:208757-209941:- gene-YER028C_NCYC1407 rna-NM_001178919.1_NCYC1407 cds-NP_010945.1_NCYC1407 99.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994144.1:219383-220567:- gene-YER028C_PE2H3 rna-NM_001178919.1_PE2H3 cds-NP_010945.1_PE2H3 98.3 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999876.1:209323-210507:- gene-YER028C_PE2H4 rna-NM_001178919.1_PE2H4 cds-NP_010945.1_PE2H4 98.3 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001137.3:210692-211876:- gene-YER028C_S288C rna-NM_001178919.1_S288C cds-NP_010945.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000020.1:31808-32991:+ gene-YER028C_SA1 rna-NM_001178919.1_SA1 cds-NP_010945.1_SA1 99.8 99.9 Unannotated 1 1 0 False False False True False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005491.1:206387-207571:- gene-YER028C_ThermosaccDry rna-NM_001178919.1_ThermosaccDry cds-NP_010945.1_ThermosaccDry 99.8 100.0 Unannotated 1 1 0 False False False False True
VR1 GCA_001738595.1 Bioethanol South America CM005459.1:205479-206663:- gene-YER028C_VR1 rna-NM_001178919.1_VR1 cds-NP_010945.1_VR1 98.3 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000009.1:203599-204783:- gene-YER028C_ZTW1 rna-NM_001178919.1_ZTW1 cds-NP_010945.1_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047491.1:207472-208663:- gene-YER028C_Sparadoxus rna-NM_001178919.1_Sparadoxus cds-NP_010945.1_Sparadoxus 83.2 100.0 Unannotated 1 1 0 False False False True False

Additional files