MIG1 (YGL035C)


Gene profile

Gene name: MIG1
Reference locus (S288C): YGL035C
Gene biotype: protein_coding

Description: Regulatory protein MIG1; Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase; regulates filamentous growth along with Mig2p in response to glucose depletion; activated in stochastic pulses of nuclear localization, shuttling between cytosol and nucleus depending on external glucose levels and its phosphorylation state; Belongs to the creA/MIG C2H2-type zinc-finger protein family

Top 10 interactors (score): SNF1 (0.998); HXK2 (0.998); CYC8 (0.998); TUP1 (0.99); SUC2 (0.954); RGT1 (0.944); CAT8 (0.936); SNF4 (0.902); SNF3 (0.902); RGT2 (0.89); MIG2 (0.866); FBP1 (0.866); GAL83 (0.864); SIP2 (0.844); RIM101 (0.827); GAL80 (0.82); SIP4 (0.813); SAK1 (0.804); GLK1 (0.799); SIP1 (0.797)

Homologues (species, bitscore): EGR1 (Homo sapiens, 77.0); Egr1 (Mus musculus, 84.0); egr1 (Danio rerio, 73.2); egr1 (Xenopus tropicalis, 79.7); Spps (Drosophila melanogaster, 75.5); egrh-2 (Caenorhabditis elegans, 73.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:433650-435164:- gene-YGL035C_AKU4011 rna-NM_001180900.1_AKU4011 cds-NP_011480.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000060.1:141018-142532:+ gene-YGL035C_BG1 rna-NM_001180900.1_BG1 cds-NP_011480.1_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:434412-435926:- gene-YGL035C_Bruggeman rna-NM_001180900.1_Bruggeman cds-NP_011480.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:432607-434121:- gene-YGL035C_CAT1 rna-NM_001180900.1_CAT1 cds-NP_011480.1_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:435122-436636:- gene-YGL035C_CBS1585 rna-NM_001180900.1_CBS1585 cds-NP_011480.1_CBS1585 99.6 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:429468-430982:- gene-YGL035C_CBS436 rna-NM_001180900.1_CBS436 cds-NP_011480.1_CBS436 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:427724-429238:- gene-YGL035C_CBS6412 rna-NM_001180900.1_CBS6412 cds-NP_011480.1_CBS6412 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:431790-433304:- gene-YGL035C_CBS6413 rna-NM_001180900.1_CBS6413 cds-NP_011480.1_CBS6413 99.6 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:431388-432902:- gene-YGL035C_CENPK1137D rna-NM_001180900.1_CENPK1137D cds-NP_011480.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:421991-423505:- gene-YGL035C_EthanolRed rna-NM_001180900.1_EthanolRed cds-NP_011480.1_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:425231-426745:- gene-YGL035C_FaliES1 rna-NM_001180900.1_FaliES1 cds-NP_011480.1_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000234.1:4570-6084:+ gene-YGL035C_JAY291 rna-NM_001180900.1_JAY291 cds-NP_011480.1_JAY291 99.9 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:431617-433131:- gene-YGL035C_MUCL30387 rna-NM_001180900.1_MUCL30387 cds-NP_011480.1_MUCL30387 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:434415-435929:- gene-YGL035C_MUCL30388 rna-NM_001180900.1_MUCL30388 cds-NP_011480.1_MUCL30388 99.6 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:430960-432474:- gene-YGL035C_MUCL39482 rna-NM_001180900.1_MUCL39482 cds-NP_011480.1_MUCL39482 99.6 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:439266-440780:- gene-YGL035C_MUCL42920 rna-NM_001180900.1_MUCL42920 cds-NP_011480.1_MUCL42920 99.4 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:431548-433062:- gene-YGL035C_NCIM3186 rna-NM_001180900.1_NCIM3186 cds-NP_011480.1_NCIM3186 99.6 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:424970-426484:- gene-YGL035C_NCYC1407 rna-NM_001180900.1_NCYC1407 cds-NP_011480.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:427580-429094:- gene-YGL035C_PE2H3 rna-NM_001180900.1_PE2H3 cds-NP_011480.1_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:432630-434144:- gene-YGL035C_PE2H4 rna-NM_001180900.1_PE2H4 cds-NP_011480.1_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:431548-433062:- gene-YGL035C_S288C rna-NM_001180900.1_S288C cds-NP_011480.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000021.1:122538-124052:+ gene-YGL035C_SA1 rna-NM_001180900.1_SA1 cds-NP_011480.1_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:444597-446111:- gene-YGL035C_ThermosaccDry rna-NM_001180900.1_ThermosaccDry cds-NP_011480.1_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:534621-536135:- gene-YGL035C_VR1 rna-NM_001180900.1_VR1 cds-NP_011480.1_VR1 99.8 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000014.1:423192-424706:- gene-YGL035C_ZTW1 rna-NM_001180900.1_ZTW1 cds-NP_011480.1_ZTW1 99.6 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:432050-433576:- gene-YGL035C_Sparadoxus rna-NM_001180900.1_Sparadoxus cds-NP_011480.1_Sparadoxus 88.8 100.0 Verified 1 1 1 False True False False False

Additional files