MID2 (YLR332W)


Gene profile

Gene name: MID2
Reference locus (S288C): YLR332W
Gene biotype: protein_coding

Description: Cell wall integrity sensor MID2; O-glycosylated plasma membrane protein; acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p; MID2 has a paralog, MTL1, that arose from the whole genome duplication

Top 10 interactors (score): ROM2 (0.995); SLG1 (0.992); WSC2 (0.968); RHO1 (0.964); ROM1 (0.964); SLT2 (0.955); WSC3 (0.943); MTL1 (0.939); PKC1 (0.938); RGD1 (0.921); FKS1 (0.897); BCK1 (0.897); MKK1 (0.887); RLM1 (0.864); SMI1 (0.821); OST6 (0.789); GAS1 (0.788); RHO2 (0.782); MKK2 (0.766); CCW12 (0.746)

Homologues (species, bitscore): clec-223 (Caenorhabditis elegans, 60.8); PERK1 (Arabidopsis thaliana, 52.4)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005306.1:739601-740731:+ gene-YLR332W_AKU4011 rna-NM_001182221.1_AKU4011 cds-NP_013436.1_AKU4011 99.9 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000080.1:6765-7895:+ gene-YLR332W_BG1 rna-NM_001182221.1_BG1 cds-NP_013436.1_BG1 99.4 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005514.1:775953-777083:+ gene-YLR332W_Bruggeman rna-NM_001182221.1_Bruggeman cds-NP_013436.1_Bruggeman 99.4 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005530.1:773506-774636:+ gene-YLR332W_CAT1 rna-NM_001182221.1_CAT1 cds-NP_013436.1_CAT1 99.4 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005370.1:774518-775648:+ gene-YLR332W_CBS1585 rna-NM_001182221.1_CBS1585 cds-NP_013436.1_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005354.1:758563-759693:+ gene-YLR332W_CBS436 rna-NM_001182221.1_CBS436 cds-NP_013436.1_CBS436 99.4 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005338.1:811929-813059:+ gene-YLR332W_CBS6412 rna-NM_001182221.1_CBS6412 cds-NP_013436.1_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005322.1:775189-776319:+ gene-YLR332W_CBS6413 rna-NM_001182221.1_CBS6413 cds-NP_013436.1_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001533.1:775295-776425:+ gene-YLR332W_CENPK1137D rna-NM_001182221.1_CENPK1137D cds-NP_013436.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005482.1:732419-733549:+ gene-YLR332W_EthanolRed rna-NM_001182221.1_EthanolRed cds-NP_013436.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005546.1:761620-762750:+ gene-YLR332W_FaliES1 rna-NM_001182221.1_FaliES1 cds-NP_013436.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000296.1:5198-6328:- gene-YLR332W_JAY291 rna-NM_001182221.1_JAY291 cds-NP_013436.1_JAY291 99.5 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005418.1:774173-775303:+ gene-YLR332W_MUCL30387 rna-NM_001182221.1_MUCL30387 cds-NP_013436.1_MUCL30387 99.2 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005450.1:779756-780886:+ gene-YLR332W_MUCL30388 rna-NM_001182221.1_MUCL30388 cds-NP_013436.1_MUCL30388 99.2 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005290.1:775758-776888:+ gene-YLR332W_MUCL39482 rna-NM_001182221.1_MUCL39482 cds-NP_013436.1_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005434.1:770920-772050:+ gene-YLR332W_MUCL42920 rna-NM_001182221.1_MUCL42920 cds-NP_013436.1_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011821.1:790650-791780:+ gene-YLR332W_NCIM3186 rna-NM_001182221.1_NCIM3186 cds-NP_013436.1_NCIM3186 99.8 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005274.1:785099-786229:+ gene-YLR332W_NCYC1407 rna-NM_001182221.1_NCYC1407 cds-NP_013436.1_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994151.1:772326-773456:+ gene-YLR332W_PE2H3 rna-NM_001182221.1_PE2H3 cds-NP_013436.1_PE2H3 99.5 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999883.1:772070-773200:+ gene-YLR332W_PE2H4 rna-NM_001182221.1_PE2H4 cds-NP_013436.1_PE2H4 99.5 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001144.5:790676-791806:+ gene-YLR332W_S288C rna-NM_001182221.1_S288C cds-NP_013436.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000007.1:257163-258293:- gene-YLR332W_SA1 rna-NM_001182221.1_SA1 cds-NP_013436.1_SA1 99.4 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005498.1:763511-764641:+ gene-YLR332W_ThermosaccDry rna-NM_001182221.1_ThermosaccDry cds-NP_013436.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005466.1:775585-776715:+ gene-YLR332W_VR1 rna-NM_001182221.1_VR1 cds-NP_013436.1_VR1 99.5 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000025.1:101901-103031:+ gene-YLR332W_ZTW1 rna-NM_001182221.1_ZTW1 cds-NP_013436.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047498.1:749980-751131:+ gene-YLR332W_Sparadoxus rna-NM_001182221.1_Sparadoxus cds-NP_013436.1_Sparadoxus 85.5 100.0 Verified 1 1 1 False True False False False

Additional files