Gene name: MIC60
Reference locus (S288C): YKR016W
Gene biotype: protein_coding
Description: Component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; Mic60p is also involved in import of intermembrane space (IMS) proteins, probably by positioning Mia40p relative to the TOM complex to receive incoming proteins; ortholog of mammalian mitofilin
Top 10 interactors (score): MIC10 (0.999); MIC12 (0.999); SAM50 (0.999); MIC27 (0.998); MIC19 (0.997); MIC26 (0.997); TOM40 (0.99); MIA40 (0.984); TOM20 (0.98); QCR2 (0.969); TOM22 (0.968); TOM70 (0.954); ATP2 (0.942); UGO1 (0.94); TIM50 (0.932); TIM11 (0.917); AIM24 (0.884); SAM37 (0.869); SAM35 (0.867); YME1 (0.839)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005305.1:455387-457009:+ | gene-YKR016W_AKU4011 | rna-NM_001179806.1_AKU4011 | cds-NP_012941.1_AKU4011 | 99.0 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000113.1:186493-188115:- | gene-YKR016W_BG1 | rna-NM_001179806.1_BG1 | cds-NP_012941.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005513.1:477060-478682:+ | gene-YKR016W_Bruggeman | rna-NM_001179806.1_Bruggeman | cds-NP_012941.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005529.1:472801-474423:+ | gene-YKR016W_CAT1 | rna-NM_001179806.1_CAT1 | cds-NP_012941.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005369.1:468127-469749:+ | gene-YKR016W_CBS1585 | rna-NM_001179806.1_CBS1585 | cds-NP_012941.1_CBS1585 | 99.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005353.1:466958-468580:+ | gene-YKR016W_CBS436 | rna-NM_001179806.1_CBS436 | cds-NP_012941.1_CBS436 | 99.8 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005337.1:452288-453910:+ | gene-YKR016W_CBS6412 | rna-NM_001179806.1_CBS6412 | cds-NP_012941.1_CBS6412 | 99.1 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005321.1:467955-469577:+ | gene-YKR016W_CBS6413 | rna-NM_001179806.1_CBS6413 | cds-NP_012941.1_CBS6413 | 99.0 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001532.1:469422-471044:+ | gene-YKR016W_CENPK1137D | rna-NM_001179806.1_CENPK1137D | cds-NP_012941.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005481.1:465855-467477:+ | gene-YKR016W_EthanolRed | rna-NM_001179806.1_EthanolRed | cds-NP_012941.1_EthanolRed | 99.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005545.1:468785-470407:+ | gene-YKR016W_FaliES1 | rna-NM_001179806.1_FaliES1 | cds-NP_012941.1_FaliES1 | 99.0 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000077.1:83351-84973:- | gene-YKR016W_JAY291 | rna-NM_001179806.1_JAY291 | cds-NP_012941.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005417.1:476377-477999:+ | gene-YKR016W_MUCL30387 | rna-NM_001179806.1_MUCL30387 | cds-NP_012941.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005449.1:472067-473689:+ | gene-YKR016W_MUCL30388 | rna-NM_001179806.1_MUCL30388 | cds-NP_012941.1_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005289.1:467444-469066:+ | gene-YKR016W_MUCL39482 | rna-NM_001179806.1_MUCL39482 | cds-NP_012941.1_MUCL39482 | 99.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005433.1:473220-474842:+ | gene-YKR016W_MUCL42920 | rna-NM_001179806.1_MUCL42920 | cds-NP_012941.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011820.1:469706-471328:+ | gene-YKR016W_NCIM3186 | rna-NM_001179806.1_NCIM3186 | cds-NP_012941.1_NCIM3186 | 99.0 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005273.1:467651-469273:+ | gene-YKR016W_NCYC1407 | rna-NM_001179806.1_NCYC1407 | cds-NP_012941.1_NCYC1407 | 99.0 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994150.1:492637-494259:+ | gene-YKR016W_PE2H3 | rna-NM_001179806.1_PE2H3 | cds-NP_012941.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999882.1:477360-478982:+ | gene-YKR016W_PE2H4 | rna-NM_001179806.1_PE2H4 | cds-NP_012941.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001143.9:469717-471339:+ | gene-YKR016W_S288C | rna-NM_001179806.1_S288C | cds-NP_012941.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000078.1:42409-44031:- | gene-YKR016W_SA1 | rna-NM_001179806.1_SA1 | cds-NP_012941.1_SA1 | 99.0 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005497.1:468040-469662:+ | gene-YKR016W_ThermosaccDry | rna-NM_001179806.1_ThermosaccDry | cds-NP_012941.1_ThermosaccDry | 99.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005465.1:467657-469279:+ | gene-YKR016W_VR1 | rna-NM_001179806.1_VR1 | cds-NP_012941.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000022.1:466087-467709:+ | gene-YKR016W_ZTW1 | rna-NM_001179806.1_ZTW1 | cds-NP_012941.1_ZTW1 | 99.1 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047497.1:491541-493163:+ | gene-YKR016W_Sparadoxus | rna-NM_001179806.1_Sparadoxus | cds-NP_012941.1_Sparadoxus | 90.2 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |