Gene name: MIC10
Reference locus (S288C): YCL057C-A
Gene biotype: protein_coding
Description: Conserved component of the MICOS complex; MICOS (formerly MINOS or MitOS) is a mitochondrial inner membrane complex that extends into the intermembrane space and has a role in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane; forms a subcomplex with Mic12p and Mic27p whose assembly and stability requires cardiolipin; homo-oligomers cause membrane bending; ortholog of human MINOS1
Top 10 interactors (score): MIC60 (0.999); MIC19 (0.998); SAM50 (0.998); MIC12 (0.998); MIC26 (0.998); MIC27 (0.998); TOM40 (0.941); SAM37 (0.886); TIM11 (0.884); TOM70 (0.884); ETR1 (0.874); MIA40 (0.847); TOM22 (0.814); UGO1 (0.779); RCF2 (0.779); TOM5 (0.737); AIM24 (0.73); TOM20 (0.712); CMG1 (0.712); RCF1 (0.709)
Homologues (species, bitscore): MINOS1 (Homo sapiens, 52.4); Minos1 (Mus musculus, 50.8); minos1 (Danio rerio, 56.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005297.1:25325-25618:- | gene-YCL057C-A_AKU4011 | rna-NM_001184448.1_AKU4011 | cds-NP_065435.1_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000090.1:10240-10533:- | gene-YCL057C-A_BG1 | rna-NM_001184448.1_BG1 | cds-NP_065435.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005505.1:12740-13033:- | gene-YCL057C-A_Bruggeman | rna-NM_001184448.1_Bruggeman | cds-NP_065435.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005521.1:25210-25503:- | gene-YCL057C-A_CAT1 | rna-NM_001184448.1_CAT1 | cds-NP_065435.1_CAT1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005361.1:26010-26303:- | gene-YCL057C-A_CBS1585 | rna-NM_001184448.1_CBS1585 | cds-NP_065435.1_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005345.1:24556-24849:- | gene-YCL057C-A_CBS436 | rna-NM_001184448.1_CBS436 | cds-NP_065435.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005329.1:13769-14062:- | gene-YCL057C-A_CBS6412 | rna-NM_001184448.1_CBS6412 | cds-NP_065435.1_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005313.1:24782-25075:- | gene-YCL057C-A_CBS6413 | rna-NM_001184448.1_CBS6413 | cds-NP_065435.1_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001524.1:23626-23919:- | gene-YCL057C-A_CENPK1137D | rna-NM_001184448.1_CENPK1137D | cds-NP_065435.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005473.1:23558-23851:- | gene-YCL057C-A_EthanolRed | rna-NM_001184448.1_EthanolRed | cds-NP_065435.1_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005537.1:24320-24613:- | gene-YCL057C-A_FaliES1 | rna-NM_001184448.1_FaliES1 | cds-NP_065435.1_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000225.1:59721-60014:+ | gene-YCL057C-A_JAY291 | rna-NM_001184448.1_JAY291 | cds-NP_065435.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005409.1:11745-12038:- | gene-YCL057C-A_MUCL30387 | rna-NM_001184448.1_MUCL30387 | cds-NP_065435.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005441.1:12037-12330:- | gene-YCL057C-A_MUCL30388 | rna-NM_001184448.1_MUCL30388 | cds-NP_065435.1_MUCL30388 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005281.1:26394-26687:- | gene-YCL057C-A_MUCL39482 | rna-NM_001184448.1_MUCL39482 | cds-NP_065435.1_MUCL39482 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005425.1:12317-12610:- | gene-YCL057C-A_MUCL42920 | rna-NM_001184448.1_MUCL42920 | cds-NP_065435.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011812.1:23664-23957:- | gene-YCL057C-A_NCIM3186 | rna-NM_001184448.1_NCIM3186 | cds-NP_065435.1_NCIM3186 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005265.1:26722-27015:- | gene-YCL057C-A_NCYC1407 | rna-NM_001184448.1_NCYC1407 | cds-NP_065435.1_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994142.1:24492-24785:- | gene-YCL057C-A_PE2H3 | rna-NM_001184448.1_PE2H3 | cds-NP_065435.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999874.1:24449-24742:- | gene-YCL057C-A_PE2H4 | rna-NM_001184448.1_PE2H4 | cds-NP_065435.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001135.5:24032-24325:- | gene-YCL057C-A_S288C | rna-NM_001184448.1_S288C | cds-NP_065435.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000061.1:11184-11477:- | gene-YCL057C-A_SA1 | rna-NM_001184448.1_SA1 | cds-NP_065435.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005489.1:24639-24932:- | gene-YCL057C-A_ThermosaccDry | rna-NM_001184448.1_ThermosaccDry | cds-NP_065435.1_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005457.1:29927-30220:- | gene-YCL057C-A_VR1 | rna-NM_001184448.1_VR1 | cds-NP_065435.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000004.1:24865-25158:- | gene-YCL057C-A_ZTW1 | rna-NM_001184448.1_ZTW1 | cds-NP_065435.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047489.1:54558-54851:- | gene-YCL057C-A_Sparadoxus | rna-NM_001184448.1_Sparadoxus | cds-NP_065435.1_Sparadoxus | 93.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |