Gene name: MHO1
Reference locus (S288C): YJR008W
Gene biotype: protein_coding
Description: MEMO1 family protein YJR008W; Protein of unknown function; inhibits haploid invasive growth when overexpressed; synthetically lethal with phospholipase C (PLC1); expression induced by mild heat-stress on a non-fermentable carbon source, upon entry into stationary phase and upon nitrogen deprivation; repressed by inosine and choline in an Opi1p-dependent manner; highly conserved from bacteria to human; Memo, the human homolog, is an ErbB2 interacting protein with an essential function in cell motility
Top 10 interactors (score): OM45 (0.895); GLC3 (0.895); SYM1 (0.738); GPX1 (0.735); STF2 (0.734); UIP4 (0.73); DCS2 (0.727); IPK1 (0.712); NHX1 (0.702); RPL32 (0.684); INO4 (0.674); INO2 (0.67); YKL091C (0.656); VIP1 (0.651); YJR096W (0.63); TFS1 (0.624); YLR345W (0.619); MSC1 (0.614); IGD1 (0.583); KCS1 (0.572)
Homologues (species, bitscore): MEMO1 (Homo sapiens, 196.1); Memo1 (Mus musculus, 197.6); memo1 (Danio rerio, 197.2); memo1 (Xenopus tropicalis, 176.0); CG8031 (Drosophila melanogaster, 210.7); tag-253 (Caenorhabditis elegans, 194.9); AT2G25280 (Arabidopsis thaliana, 193.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005304.1:435601-436617:+ | gene-YJR008W_AKU4011 | rna-NM_001181665.1_AKU4011 | cds-NP_012541.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000190.1:176110-177126:- | gene-YJR008W_BG1 | rna-NM_001181665.1_BG1 | cds-NP_012541.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005512.1:449698-450714:+ | gene-YJR008W_Bruggeman | rna-NM_001181665.1_Bruggeman | cds-NP_012541.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005528.1:453639-454655:+ | gene-YJR008W_CAT1 | rna-NM_001181665.1_CAT1 | cds-NP_012541.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005368.1:447188-448204:+ | gene-YJR008W_CBS1585 | rna-NM_001181665.1_CBS1585 | cds-NP_012541.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005352.1:466169-467185:+ | gene-YJR008W_CBS436 | rna-NM_001181665.1_CBS436 | cds-NP_012541.1_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005336.1:435415-436431:+ | gene-YJR008W_CBS6412 | rna-NM_001181665.1_CBS6412 | cds-NP_012541.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005320.1:437644-438660:+ | gene-YJR008W_CBS6413 | rna-NM_001181665.1_CBS6413 | cds-NP_012541.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001531.1:434855-435871:+ | gene-YJR008W_CENPK1137D | rna-NM_001181665.1_CENPK1137D | cds-NP_012541.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005480.1:440577-441593:+ | gene-YJR008W_EthanolRed | rna-NM_001181665.1_EthanolRed | cds-NP_012541.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005544.1:451718-452734:+ | gene-YJR008W_FaliES1 | rna-NM_001181665.1_FaliES1 | cds-NP_012541.1_FaliES1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000321.1:512-1528:- | gene-YJR008W_JAY291 | rna-NM_001181665.1_JAY291 | cds-NP_012541.1_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005416.1:450025-451041:+ | gene-YJR008W_MUCL30387 | rna-NM_001181665.1_MUCL30387 | cds-NP_012541.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005448.1:446547-447563:+ | gene-YJR008W_MUCL30388 | rna-NM_001181665.1_MUCL30388 | cds-NP_012541.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005288.1:440522-441538:+ | gene-YJR008W_MUCL39482 | rna-NM_001181665.1_MUCL39482 | cds-NP_012541.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005432.1:445960-446976:+ | gene-YJR008W_MUCL42920 | rna-NM_001181665.1_MUCL42920 | cds-NP_012541.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011819.1:452409-453425:+ | gene-YJR008W_NCIM3186 | rna-NM_001181665.1_NCIM3186 | cds-NP_012541.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005272.1:438414-439430:+ | gene-YJR008W_NCYC1407 | rna-NM_001181665.1_NCYC1407 | cds-NP_012541.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994149.1:456823-457839:+ | gene-YJR008W_PE2H3 | rna-NM_001181665.1_PE2H3 | cds-NP_012541.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999881.1:450517-451533:+ | gene-YJR008W_PE2H4 | rna-NM_001181665.1_PE2H4 | cds-NP_012541.1_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001142.9:452430-453446:+ | gene-YJR008W_S288C | rna-NM_001181665.1_S288C | cds-NP_012541.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000003.1:248441-249457:+ | gene-YJR008W_SA1 | rna-NM_001181665.1_SA1 | cds-NP_012541.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005496.1:445377-446393:+ | gene-YJR008W_ThermosaccDry | rna-NM_001181665.1_ThermosaccDry | cds-NP_012541.1_ThermosaccDry | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005464.1:447742-448758:+ | gene-YJR008W_VR1 | rna-NM_001181665.1_VR1 | cds-NP_012541.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000021.1:425378-426394:+ | gene-YJR008W_ZTW1 | rna-NM_001181665.1_ZTW1 | cds-NP_012541.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047496.1:450248-451267:+ | gene-YJR008W_Sparadoxus | rna-NM_001181665.1_Sparadoxus | cds-NP_012541.1_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |