MHF2 (YDL160C-A)


Gene profile

Gene name: MHF2
Reference locus (S288C): YDL160C-A
Gene biotype: protein_coding

Description: Component of the heterotetrameric MHF histone-fold complex; in humans the MHF complex interacts with both DNA and Mph1p ortholog FANCM to stabilize and remodel blocked replication forks and repair damaged DNA; mhf2 srs2 double mutants are MMS hypersensitive; orthologous to human centromere constitutive-associated network (CCAN) subunit CENP-X, also known as MHF2

Top 10 interactors (score): MHF1 (0.999); MPH1 (0.908); MTE1 (0.881); WIP1 (0.702); CNN1 (0.657); NKP1 (0.642); MCM16 (0.563); LDB17 (0.562); AME1 (0.535); OKP1 (0.533); CHL4 (0.531); IML3 (0.531); NCB2 (0.526); ERT1 (0.526); MAK16 (0.499); NKP2 (0.499); TFG1 (0.499); RTK1 (0.497); SDA1 (0.487); YIF1 (0.487)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:153783-154025:- gene-YDL160C-A_AKU4011 rna-NM_001184530.1_AKU4011 cds-NP_878060.1_AKU4011 99.5 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:395690-395932:+ gene-YDL160C-A_BG1 rna-NM_001184530.1_BG1 cds-NP_878060.1_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:169834-170076:- gene-YDL160C-A_Bruggeman rna-NM_001184530.1_Bruggeman cds-NP_878060.1_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:168170-168412:- gene-YDL160C-A_CAT1 rna-NM_001184530.1_CAT1 cds-NP_878060.1_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:151819-152061:- gene-YDL160C-A_CBS1585 rna-NM_001184530.1_CBS1585 cds-NP_878060.1_CBS1585 99.5 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005346.1:168777-169019:- gene-YDL160C-A_CBS436 rna-NM_001184530.1_CBS436 cds-NP_878060.1_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:151434-151676:- gene-YDL160C-A_CBS6412 rna-NM_001184530.1_CBS6412 cds-NP_878060.1_CBS6412 99.1 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:170245-170487:- gene-YDL160C-A_CBS6413 rna-NM_001184530.1_CBS6413 cds-NP_878060.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:168041-168283:- gene-YDL160C-A_CENPK1137D rna-NM_001184530.1_CENPK1137D cds-NP_878060.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:165230-165472:- gene-YDL160C-A_EthanolRed rna-NM_001184530.1_EthanolRed cds-NP_878060.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:170556-170798:- gene-YDL160C-A_FaliES1 rna-NM_001184530.1_FaliES1 cds-NP_878060.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000032.1:48736-48978:+ gene-YDL160C-A_JAY291 rna-NM_001184530.1_JAY291 cds-NP_878060.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:168143-168385:- gene-YDL160C-A_MUCL30387 rna-NM_001184530.1_MUCL30387 cds-NP_878060.1_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:159807-160049:- gene-YDL160C-A_MUCL30388 rna-NM_001184530.1_MUCL30388 cds-NP_878060.1_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:152962-153204:- gene-YDL160C-A_MUCL39482 rna-NM_001184530.1_MUCL39482 cds-NP_878060.1_MUCL39482 99.5 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe MBVV01000307.1:16174-16416:+ gene-YDL160C-A_MUCL42920 rna-NM_001184530.1_MUCL42920 cds-NP_878060.1_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:169289-169531:- gene-YDL160C-A_NCIM3186 rna-NM_001184530.1_NCIM3186 cds-NP_878060.1_NCIM3186 100.0 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:152902-153144:- gene-YDL160C-A_NCYC1407 rna-NM_001184530.1_NCYC1407 cds-NP_878060.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:160161-160403:- gene-YDL160C-A_PE2H3 rna-NM_001184530.1_PE2H3 cds-NP_878060.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:160165-160407:- gene-YDL160C-A_PE2H4 rna-NM_001184530.1_PE2H4 cds-NP_878060.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:169366-169608:- gene-YDL160C-A_S288C rna-NM_001184530.1_S288C cds-NP_878060.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000043.1:34925-35167:- gene-YDL160C-A_SA1 rna-NM_001184530.1_SA1 cds-NP_878060.1_SA1 99.5 100.0 Verified 1 1 1 True True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:170316-170558:- gene-YDL160C-A_ThermosaccDry rna-NM_001184530.1_ThermosaccDry cds-NP_878060.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:170932-171174:- gene-YDL160C-A_VR1 rna-NM_001184530.1_VR1 cds-NP_878060.1_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:168446-168688:- gene-YDL160C-A_ZTW1 rna-NM_001184530.1_ZTW1 cds-NP_878060.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:170586-170828:- gene-YDL160C-A_Sparadoxus rna-NM_001184530.1_Sparadoxus cds-NP_878060.1_Sparadoxus 87.7 99.5 Verified 1 1 1 False True False False False

Additional files