Gene name: MHF1
Reference locus (S288C): YOL086W-A
Gene biotype: protein_coding
Description: Component of the heterotetrameric MHF histone-fold complex; in humans the MHF complex interacts with both DNA and Mph1p ortholog FANCM, a Fanconi anemia complementation group protein, to stabilize and remodel blocked replication forks and repair damaged DNA; mhf1 srs2 double mutants are MMS hypersensitive; ortholog of human centromere constitutive-associated network (CCAN) subunit CENP-S, also known as MHF1
Top 10 interactors (score): MHF2 (0.999); MPH1 (0.923); MTE1 (0.922); WIP1 (0.727); CNN1 (0.711); AME1 (0.63); NKP1 (0.575); NKP2 (0.574); RTK1 (0.573); SRS2 (0.539); MLH3 (0.509); MCM16 (0.499); CTF3 (0.499); MCM22 (0.491); CAF120 (0.485); OKP1 (0.48); CEP3 (0.452); IML3 (0.451); CHL4 (0.451); CTF13 (0.45)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:142522-142794:+ | gene-YOL086W-A_AKU4011 | rna-NM_001184492.1_AKU4011 | cds-NP_076910.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:107624-107896:+ | gene-YOL086W-A_BG1 | rna-NM_001184492.1_BG1 | cds-NP_076910.1_BG1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:144068-144340:+ | gene-YOL086W-A_Bruggeman | rna-NM_001184492.1_Bruggeman | cds-NP_076910.1_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:143400-143672:+ | gene-YOL086W-A_CAT1 | rna-NM_001184492.1_CAT1 | cds-NP_076910.1_CAT1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:136932-137204:+ | gene-YOL086W-A_CBS1585 | rna-NM_001184492.1_CBS1585 | cds-NP_076910.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:142205-142477:+ | gene-YOL086W-A_CBS436 | rna-NM_001184492.1_CBS436 | cds-NP_076910.1_CBS436 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:137090-137362:+ | gene-YOL086W-A_CBS6412 | rna-NM_001184492.1_CBS6412 | cds-NP_076910.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:143795-144067:+ | gene-YOL086W-A_CBS6413 | rna-NM_001184492.1_CBS6413 | cds-NP_076910.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:153138-153410:+ | gene-YOL086W-A_CENPK1137D | rna-NM_001184492.1_CENPK1137D | cds-NP_076910.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:140094-140366:+ | gene-YOL086W-A_EthanolRed | rna-NM_001184492.1_EthanolRed | cds-NP_076910.1_EthanolRed | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:142421-142693:+ | gene-YOL086W-A_FaliES1 | rna-NM_001184492.1_FaliES1 | cds-NP_076910.1_FaliES1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000160.1:783-1055:- | gene-YOL086W-A_JAY291 | rna-NM_001184492.1_JAY291 | cds-NP_076910.1_JAY291 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:148270-148542:+ | gene-YOL086W-A_MUCL30387 | rna-NM_001184492.1_MUCL30387 | cds-NP_076910.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:151451-151723:+ | gene-YOL086W-A_MUCL30388 | rna-NM_001184492.1_MUCL30388 | cds-NP_076910.1_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:144853-145125:+ | gene-YOL086W-A_MUCL39482 | rna-NM_001184492.1_MUCL39482 | cds-NP_076910.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:160620-160892:+ | gene-YOL086W-A_MUCL42920 | rna-NM_001184492.1_MUCL42920 | cds-NP_076910.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:159062-159334:+ | gene-YOL086W-A_NCIM3186 | rna-NM_001184492.1_NCIM3186 | cds-NP_076910.1_NCIM3186 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:151450-151722:+ | gene-YOL086W-A_NCYC1407 | rna-NM_001184492.1_NCYC1407 | cds-NP_076910.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:134742-135014:+ | gene-YOL086W-A_PE2H3 | rna-NM_001184492.1_PE2H3 | cds-NP_076910.1_PE2H3 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:145731-146002:+ | gene-YOL086W-A_PE2H4 | rna-NM_001184492.1_PE2H4 | cds-NP_076910.1_PE2H4 | 97.0 | 99.6 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:159173-159445:+ | gene-YOL086W-A_S288C | rna-NM_001184492.1_S288C | cds-NP_076910.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:127054-127326:+ | gene-YOL086W-A_SA1 | rna-NM_001184492.1_SA1 | cds-NP_076910.1_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:141429-141701:+ | gene-YOL086W-A_ThermosaccDry | rna-NM_001184492.1_ThermosaccDry | cds-NP_076910.1_ThermosaccDry | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:141998-142269:+ | gene-YOL086W-A_VR1 | rna-NM_001184492.1_VR1 | cds-NP_076910.1_VR1 | 97.0 | 99.6 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:141126-141398:+ | gene-YOL086W-A_ZTW1 | rna-NM_001184492.1_ZTW1 | cds-NP_076910.1_ZTW1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:144600-144872:+ | gene-YOL086W-A_Sparadoxus | rna-NM_001184492.1_Sparadoxus | cds-NP_076910.1_Sparadoxus | 85.3 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |