MGT1 (YDL200C)


Gene profile

Gene name: MGT1
Reference locus (S288C): YDL200C
Gene biotype: protein_coding

Description: Methylated-dna-[protein]-cysteine s-methyltransferase; DNA repair methyltransferase (6-O-methylguanine-DNA methylase); involved in protection against DNA alkylation damage; Belongs to the MGMT family

Top 10 interactors (score): MLH1 (0.935); MAG1 (0.923); MSH6 (0.874); MSH2 (0.807); YNL092W (0.713); MTQ1 (0.711); UFD4 (0.703); TRM3 (0.695); APN2 (0.687); MSH3 (0.657); RKM5 (0.652); RAD14 (0.652); UBR1 (0.642); OGG1 (0.639); OMS1 (0.633); DPH5 (0.62); BMT5 (0.619); STE14 (0.614); PPM2 (0.614); PHR1 (0.604)

Homologues (species, bitscore): MGMT (Homo sapiens, 60.1); Mgmt (Mus musculus, 57.8); mgmt (Danio rerio, 52.4); mgmt (Xenopus tropicalis, 51.6); agt (Drosophila melanogaster, 91.7); agt-1 (Caenorhabditis elegans, 84.3)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005298.1:83986-84552:- gene-YDL200C_AKU4011 rna-NM_001180260.1_AKU4011 cds-NP_010081.2_AKU4011 99.8 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000102.1:464119-464685:+ gene-YDL200C_BG1 rna-NM_001180260.1_BG1 cds-NP_010081.2_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005506.1:100362-100928:- gene-YDL200C_Bruggeman rna-NM_001180260.1_Bruggeman cds-NP_010081.2_Bruggeman 99.8 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005522.1:102485-103051:- gene-YDL200C_CAT1 rna-NM_001180260.1_CAT1 cds-NP_010081.2_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005362.1:82837-83403:- gene-YDL200C_CBS1585 rna-NM_001180260.1_CBS1585 cds-NP_010081.2_CBS1585 99.8 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005356.1:297738-298304:- gene-YDL200C_CBS436 rna-NM_001180260.1_CBS436 cds-NP_010081.2_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005330.1:82951-83517:- gene-YDL200C_CBS6412 rna-NM_001180260.1_CBS6412 cds-NP_010081.2_CBS6412 99.8 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005314.1:100495-101061:- gene-YDL200C_CBS6413 rna-NM_001180260.1_CBS6413 cds-NP_010081.2_CBS6413 99.8 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001525.1:99167-99733:- gene-YDL200C_CENPK1137D rna-NM_001180260.1_CENPK1137D cds-NP_010081.2_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005474.1:96637-97203:- gene-YDL200C_EthanolRed rna-NM_001180260.1_EthanolRed cds-NP_010081.2_EthanolRed 99.8 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005538.1:101243-101809:- gene-YDL200C_FaliES1 rna-NM_001180260.1_FaliES1 cds-NP_010081.2_FaliES1 99.8 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000344.1:17444-18010:+ gene-YDL200C_JAY291 rna-NM_001180260.1_JAY291 cds-NP_010081.2_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005410.1:98613-99179:- gene-YDL200C_MUCL30387 rna-NM_001180260.1_MUCL30387 cds-NP_010081.2_MUCL30387 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005442.1:88180-88746:- gene-YDL200C_MUCL30388 rna-NM_001180260.1_MUCL30388 cds-NP_010081.2_MUCL30388 99.8 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005282.1:83681-84247:- gene-YDL200C_MUCL39482 rna-NM_001180260.1_MUCL39482 cds-NP_010081.2_MUCL39482 99.8 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005426.1:99748-100314:- gene-YDL200C_MUCL42920 rna-NM_001180260.1_MUCL42920 cds-NP_010081.2_MUCL42920 99.2 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011813.1:100424-100990:- gene-YDL200C_NCIM3186 rna-NM_001180260.1_NCIM3186 cds-NP_010081.2_NCIM3186 98.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005266.1:83638-84204:- gene-YDL200C_NCYC1407 rna-NM_001180260.1_NCYC1407 cds-NP_010081.2_NCYC1407 99.8 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994143.1:91388-91954:- gene-YDL200C_PE2H3 rna-NM_001180260.1_PE2H3 cds-NP_010081.2_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999875.1:91398-91964:- gene-YDL200C_PE2H4 rna-NM_001180260.1_PE2H4 cds-NP_010081.2_PE2H4 99.6 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001136.10:100501-101067:- gene-YDL200C_S288C rna-NM_001180260.1_S288C cds-NP_010081.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000090.1:14991-15557:- gene-YDL200C_SA1 rna-NM_001180260.1_SA1 cds-NP_010081.2_SA1 99.6 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005490.1:101002-101568:- gene-YDL200C_ThermosaccDry rna-NM_001180260.1_ThermosaccDry cds-NP_010081.2_ThermosaccDry 99.8 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005458.1:101938-102504:- gene-YDL200C_VR1 rna-NM_001180260.1_VR1 cds-NP_010081.2_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000006.1:99676-100242:- gene-YDL200C_ZTW1 rna-NM_001180260.1_ZTW1 cds-NP_010081.2_ZTW1 99.8 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047490.1:103047-103613:- gene-YDL200C_Sparadoxus rna-NM_001180260.1_Sparadoxus cds-NP_010081.2_Sparadoxus 88.0 100.0 Verified 1 1 1 False True False False False

Additional files