Gene name: MGS1
Reference locus (S288C): YNL218W
Gene biotype: protein_coding
Description: Protein with DNA-dependent ATPase and ssDNA annealing activities; involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP); forms nuclear foci upon DNA replication stress; Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily
Top 10 interactors (score): SGS1 (0.984); RAD18 (0.956); RAD5 (0.928); POL31 (0.91); SRS2 (0.882); RAD6 (0.872); UBC13 (0.864); REV1 (0.841); RAD51 (0.838); REV3 (0.835); POL32 (0.82); DNA2 (0.819); POL3 (0.817); POL30 (0.802); TOP3 (0.792); IRC20 (0.792); RAD30 (0.792); ELG1 (0.79); MCM2 (0.771); PCM1 (0.76)
Homologues (species, bitscore): WRNIP1 (Homo sapiens, 370.2); Wrnip1 (Mus musculus, 371.7); wrnip1 (Danio rerio, 385.2); wrnip1 (Xenopus tropicalis, 209.5); RfC4 (Drosophila melanogaster, 54.3); F44B9.8 (Caenorhabditis elegans, 51.2); AT1G24290 (Arabidopsis thaliana, 345.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005308.1:232020-233783:+ | gene-YNL218W_AKU4011 | rna-NM_001183056.1_AKU4011 | cds-NP_014181.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000155.1:135963-137726:+ | gene-YNL218W_BG1 | rna-NM_001183056.1_BG1 | cds-NP_014181.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005516.1:242063-243826:+ | gene-YNL218W_Bruggeman | rna-NM_001183056.1_Bruggeman | cds-NP_014181.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005532.1:249217-250980:+ | gene-YNL218W_CAT1 | rna-NM_001183056.1_CAT1 | cds-NP_014181.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005372.1:232415-234178:+ | gene-YNL218W_CBS1585 | rna-NM_001183056.1_CBS1585 | cds-NP_014181.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005356.1:227494-229257:+ | gene-YNL218W_CBS436 | rna-NM_001183056.1_CBS436 | cds-NP_014181.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005340.1:228453-230216:+ | gene-YNL218W_CBS6412 | rna-NM_001183056.1_CBS6412 | cds-NP_014181.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005324.1:229099-230862:+ | gene-YNL218W_CBS6413 | rna-NM_001183056.1_CBS6413 | cds-NP_014181.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001535.1:232039-233802:+ | gene-YNL218W_CENPK1137D | rna-NM_001183056.1_CENPK1137D | cds-NP_014181.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005484.1:229657-231420:+ | gene-YNL218W_EthanolRed | rna-NM_001183056.1_EthanolRed | cds-NP_014181.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005548.1:224399-226162:+ | gene-YNL218W_FaliES1 | rna-NM_001183056.1_FaliES1 | cds-NP_014181.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000082.1:135556-137319:+ | gene-YNL218W_JAY291 | rna-NM_001183056.1_JAY291 | cds-NP_014181.1_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005420.1:237599-239362:+ | gene-YNL218W_MUCL30387 | rna-NM_001183056.1_MUCL30387 | cds-NP_014181.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005452.1:236180-237943:+ | gene-YNL218W_MUCL30388 | rna-NM_001183056.1_MUCL30388 | cds-NP_014181.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005292.1:229905-231668:+ | gene-YNL218W_MUCL39482 | rna-NM_001183056.1_MUCL39482 | cds-NP_014181.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005436.1:232161-233924:+ | gene-YNL218W_MUCL42920 | rna-NM_001183056.1_MUCL42920 | cds-NP_014181.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011823.1:238207-239970:+ | gene-YNL218W_NCIM3186 | rna-NM_001183056.1_NCIM3186 | cds-NP_014181.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005276.1:231995-233758:+ | gene-YNL218W_NCYC1407 | rna-NM_001183056.1_NCYC1407 | cds-NP_014181.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994153.1:228901-230664:+ | gene-YNL218W_PE2H3 | rna-NM_001183056.1_PE2H3 | cds-NP_014181.1_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999885.1:228289-230052:+ | gene-YNL218W_PE2H4 | rna-NM_001183056.1_PE2H4 | cds-NP_014181.1_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001146.8:238238-240001:+ | gene-YNL218W_S288C | rna-NM_001183056.1_S288C | cds-NP_014181.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000040.1:12308-14071:- | gene-YNL218W_SA1 | rna-NM_001183056.1_SA1 | cds-NP_014181.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005500.1:225255-227018:+ | gene-YNL218W_ThermosaccDry | rna-NM_001183056.1_ThermosaccDry | cds-NP_014181.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005468.1:244257-246020:+ | gene-YNL218W_VR1 | rna-NM_001183056.1_VR1 | cds-NP_014181.1_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000030.1:135584-137347:+ | gene-YNL218W_ZTW1 | rna-NM_001183056.1_ZTW1 | cds-NP_014181.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047500.1:235658-237418:+ | gene-YNL218W_Sparadoxus | rna-NM_001183056.1_Sparadoxus | cds-NP_014181.1_Sparadoxus | 89.3 | 99.8 | Verified | 1 | 1 | 1 | False | True | False | False | False |