Gene name: MGM1
Reference locus (S288C): YOR211C
Gene biotype: protein_coding
Description: Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p; required for mitochondrial morphology, fusion, and genome maintenance; promotes membrane bending; exists as long and short form with different distributions; ratio of long to short forms is regulated by Psd1p; homolog of human OPA1 involved in autosomal dominant optic atrophy
Top 10 interactors (score): FZO1 (0.999); UGO1 (0.995); FIS1 (0.988); PCP1 (0.977); APL3 (0.929); MDV1 (0.913); CAF4 (0.913); OMA1 (0.911); TIM23 (0.911); APM4 (0.908); DNM1 (0.903); CHC1 (0.89); SWA2 (0.885); INP53 (0.866); INP51 (0.866); INP52 (0.866); MDM10 (0.862); YNK1 (0.861); PAN1 (0.855); END3 (0.855)
Homologues (species, bitscore): DNM1 (Homo sapiens, 189.5); Dnm1 (Mus musculus, 189.1); dnm1b (Danio rerio, 191.0); dnm1 (Xenopus tropicalis, 179.5); Drp1 (Drosophila melanogaster, 174.9); dyn-1 (Caenorhabditis elegans, 172.6); DRP3B (Arabidopsis thaliana, 182.6)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:729705-732350:- | gene-YOR211C_AKU4011 | rna-NM_001183630.1_AKU4011 | cds-NP_014854.2_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:131744-134389:- | gene-YOR211C_BG1 | rna-NM_001183630.1_BG1 | cds-NP_014854.2_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:714541-717186:- | gene-YOR211C_Bruggeman | rna-NM_001183630.1_Bruggeman | cds-NP_014854.2_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:715819-718464:- | gene-YOR211C_CAT1 | rna-NM_001183630.1_CAT1 | cds-NP_014854.2_CAT1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:712693-715338:- | gene-YOR211C_CBS1585 | rna-NM_001183630.1_CBS1585 | cds-NP_014854.2_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:711384-714029:- | gene-YOR211C_CBS436 | rna-NM_001183630.1_CBS436 | cds-NP_014854.2_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:709811-712456:- | gene-YOR211C_CBS6412 | rna-NM_001183630.1_CBS6412 | cds-NP_014854.2_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 0 | False | False | True | False | False |
CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:718450-721095:- | gene-YOR211C_CBS6413 | rna-NM_001183630.1_CBS6413 | cds-NP_014854.2_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:738685-741330:- | gene-YOR211C_CENPK1137D | rna-NM_001183630.1_CENPK1137D | cds-NP_014854.2_CENPK1137D | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:705846-708491:- | gene-YOR211C_EthanolRed | rna-NM_001183630.1_EthanolRed | cds-NP_014854.2_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:711243-713888:- | gene-YOR211C_FaliES1 | rna-NM_001183630.1_FaliES1 | cds-NP_014854.2_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:112871-115516:+ | gene-YOR211C_JAY291 | rna-NM_001183630.1_JAY291 | cds-NP_014854.2_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:718506-721151:- | gene-YOR211C_MUCL30387 | rna-NM_001183630.1_MUCL30387 | cds-NP_014854.2_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:725922-728567:- | gene-YOR211C_MUCL30388 | rna-NM_001183630.1_MUCL30388 | cds-NP_014854.2_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:720022-722667:- | gene-YOR211C_MUCL39482 | rna-NM_001183630.1_MUCL39482 | cds-NP_014854.2_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:729606-732251:- | gene-YOR211C_MUCL42920 | rna-NM_001183630.1_MUCL42920 | cds-NP_014854.2_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:738813-741458:- | gene-YOR211C_NCIM3186 | rna-NM_001183630.1_NCIM3186 | cds-NP_014854.2_NCIM3186 | 98.0 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:720122-722767:- | gene-YOR211C_NCYC1407 | rna-NM_001183630.1_NCYC1407 | cds-NP_014854.2_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:719517-722162:- | gene-YOR211C_PE2H3 | rna-NM_001183630.1_PE2H3 | cds-NP_014854.2_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:729894-732539:- | gene-YOR211C_PE2H4 | rna-NM_001183630.1_PE2H4 | cds-NP_014854.2_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:738924-741569:- | gene-YOR211C_S288C | rna-NM_001183630.1_S288C | cds-NP_014854.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:148924-151569:- | gene-YOR211C_SA1 | rna-NM_001183630.1_SA1 | cds-NP_014854.2_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:710428-713073:- | gene-YOR211C_ThermosaccDry | rna-NM_001183630.1_ThermosaccDry | cds-NP_014854.2_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:773958-776603:- | gene-YOR211C_VR1 | rna-NM_001183630.1_VR1 | cds-NP_014854.2_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:443328-445973:- | gene-YOR211C_ZTW1 | rna-NM_001183630.1_ZTW1 | cds-NP_014854.2_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 0 | False | False | True | False | False |
Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:716277-718916:- | gene-YOR211C_Sparadoxus | rna-NM_001183630.1_Sparadoxus | cds-NP_014854.2_Sparadoxus | 89.6 | 99.7 | Verified | 1 | 1 | 0 | False | False | True | False | False |