MGM1 (YOR211C)


Gene profile

Gene name: MGM1
Reference locus (S288C): YOR211C
Gene biotype: protein_coding

Description: Mitochondrial GTPase, present in complex with Ugo1p and Fzo1p; required for mitochondrial morphology, fusion, and genome maintenance; promotes membrane bending; exists as long and short form with different distributions; ratio of long to short forms is regulated by Psd1p; homolog of human OPA1 involved in autosomal dominant optic atrophy

Top 10 interactors (score): FZO1 (0.999); UGO1 (0.995); FIS1 (0.988); PCP1 (0.977); APL3 (0.929); MDV1 (0.913); CAF4 (0.913); OMA1 (0.911); TIM23 (0.911); APM4 (0.908); DNM1 (0.903); CHC1 (0.89); SWA2 (0.885); INP53 (0.866); INP51 (0.866); INP52 (0.866); MDM10 (0.862); YNK1 (0.861); PAN1 (0.855); END3 (0.855)

Homologues (species, bitscore): DNM1 (Homo sapiens, 189.5); Dnm1 (Mus musculus, 189.1); dnm1b (Danio rerio, 191.0); dnm1 (Xenopus tropicalis, 179.5); Drp1 (Drosophila melanogaster, 174.9); dyn-1 (Caenorhabditis elegans, 172.6); DRP3B (Arabidopsis thaliana, 182.6)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:729705-732350:- gene-YOR211C_AKU4011 rna-NM_001183630.1_AKU4011 cds-NP_014854.2_AKU4011 99.6 100.0 Verified 1 1 0 False False True False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:131744-134389:- gene-YOR211C_BG1 rna-NM_001183630.1_BG1 cds-NP_014854.2_BG1 99.9 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:714541-717186:- gene-YOR211C_Bruggeman rna-NM_001183630.1_Bruggeman cds-NP_014854.2_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:715819-718464:- gene-YOR211C_CAT1 rna-NM_001183630.1_CAT1 cds-NP_014854.2_CAT1 99.9 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:712693-715338:- gene-YOR211C_CBS1585 rna-NM_001183630.1_CBS1585 cds-NP_014854.2_CBS1585 99.6 100.0 Verified 1 1 0 False False True False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:711384-714029:- gene-YOR211C_CBS436 rna-NM_001183630.1_CBS436 cds-NP_014854.2_CBS436 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:709811-712456:- gene-YOR211C_CBS6412 rna-NM_001183630.1_CBS6412 cds-NP_014854.2_CBS6412 99.6 100.0 Mismatch 1 1 0 False False True False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:718450-721095:- gene-YOR211C_CBS6413 rna-NM_001183630.1_CBS6413 cds-NP_014854.2_CBS6413 99.6 100.0 Verified 1 1 0 False False True False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:738685-741330:- gene-YOR211C_CENPK1137D rna-NM_001183630.1_CENPK1137D cds-NP_014854.2_CENPK1137D 99.9 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:705846-708491:- gene-YOR211C_EthanolRed rna-NM_001183630.1_EthanolRed cds-NP_014854.2_EthanolRed 99.6 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:711243-713888:- gene-YOR211C_FaliES1 rna-NM_001183630.1_FaliES1 cds-NP_014854.2_FaliES1 99.6 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000381.1:112871-115516:+ gene-YOR211C_JAY291 rna-NM_001183630.1_JAY291 cds-NP_014854.2_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:718506-721151:- gene-YOR211C_MUCL30387 rna-NM_001183630.1_MUCL30387 cds-NP_014854.2_MUCL30387 99.6 100.0 Verified 1 1 0 False False True False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:725922-728567:- gene-YOR211C_MUCL30388 rna-NM_001183630.1_MUCL30388 cds-NP_014854.2_MUCL30388 99.6 100.0 Verified 1 1 0 False False True False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:720022-722667:- gene-YOR211C_MUCL39482 rna-NM_001183630.1_MUCL39482 cds-NP_014854.2_MUCL39482 99.6 100.0 Verified 1 1 0 False False True False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:729606-732251:- gene-YOR211C_MUCL42920 rna-NM_001183630.1_MUCL42920 cds-NP_014854.2_MUCL42920 99.8 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:738813-741458:- gene-YOR211C_NCIM3186 rna-NM_001183630.1_NCIM3186 cds-NP_014854.2_NCIM3186 98.0 100.0 Verified 1 1 0 False False True False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:720122-722767:- gene-YOR211C_NCYC1407 rna-NM_001183630.1_NCYC1407 cds-NP_014854.2_NCYC1407 99.6 100.0 Verified 1 1 0 False False True False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:719517-722162:- gene-YOR211C_PE2H3 rna-NM_001183630.1_PE2H3 cds-NP_014854.2_PE2H3 99.9 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:729894-732539:- gene-YOR211C_PE2H4 rna-NM_001183630.1_PE2H4 cds-NP_014854.2_PE2H4 99.9 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:738924-741569:- gene-YOR211C_S288C rna-NM_001183630.1_S288C cds-NP_014854.2_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:148924-151569:- gene-YOR211C_SA1 rna-NM_001183630.1_SA1 cds-NP_014854.2_SA1 99.9 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:710428-713073:- gene-YOR211C_ThermosaccDry rna-NM_001183630.1_ThermosaccDry cds-NP_014854.2_ThermosaccDry 99.6 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:773958-776603:- gene-YOR211C_VR1 rna-NM_001183630.1_VR1 cds-NP_014854.2_VR1 99.9 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:443328-445973:- gene-YOR211C_ZTW1 rna-NM_001183630.1_ZTW1 cds-NP_014854.2_ZTW1 99.6 100.0 Verified 1 1 0 False False True False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:716277-718916:- gene-YOR211C_Sparadoxus rna-NM_001183630.1_Sparadoxus cds-NP_014854.2_Sparadoxus 89.6 99.7 Verified 1 1 0 False False True False False

Additional files