Gene name: MGA2
Reference locus (S288C): YIR033W
Gene biotype: protein_coding
Description: ER membrane protein involved in regulation of OLE1 transcription; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting; MGA2 has a paralog, SPT23, that arose from the whole genome duplication
Top 10 interactors (score): OLE1 (0.99); RSP5 (0.986); NPL4 (0.842); SPT23 (0.819); CYB5 (0.779); ROX1 (0.667); CDC48 (0.664); ATG15 (0.645); MOT3 (0.643); TEF4 (0.604); IOC2 (0.586); UPC2 (0.571); SSM4 (0.558); ECM22 (0.557); ELO3 (0.551); UFD1 (0.549); OPI1 (0.545); UBP2 (0.545); HMS1 (0.527); TIS11 (0.509)
Homologues (species, bitscore): ANKRD65 (Homo sapiens, 67.0); Osbpl1a (Mus musculus, 58.5); ank2a (Danio rerio, 65.9); acbd6 (Xenopus tropicalis, 58.5); Ank (Drosophila melanogaster, 57.0); unc-44 (Caenorhabditis elegans, 56.6); SFC (Arabidopsis thaliana, 52.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:414351-417692:+ | gene-YIR033W_AKU4011 | rna-NM_001179555.1_AKU4011 | cds-NP_012299.1_AKU4011 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000072.1:9145-12486:- | gene-YIR033W_BG1 | rna-NM_001179555.1_BG1 | cds-NP_012299.1_BG1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:420545-423886:+ | gene-YIR033W_Bruggeman | rna-NM_001179555.1_Bruggeman | cds-NP_012299.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:405506-408847:+ | gene-YIR033W_CAT1 | rna-NM_001179555.1_CAT1 | cds-NP_012299.1_CAT1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:415303-418644:+ | gene-YIR033W_CBS1585 | rna-NM_001179555.1_CBS1585 | cds-NP_012299.1_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:407272-410613:+ | gene-YIR033W_CBS436 | rna-NM_001179555.1_CBS436 | cds-NP_012299.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005327.1:113810-117151:+ | gene-YIR033W_CBS6412 | rna-NM_001179555.1_CBS6412 | cds-NP_012299.1_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:406404-409745:+ | gene-YIR033W_CBS6413 | rna-NM_001179555.1_CBS6413 | cds-NP_012299.1_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:407785-411124:+ | gene-YIR033W_CENPK1137D | rna-NM_001179555.1_CENPK1137D | cds-NP_012299.1_CENPK1137D | 99.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:397267-400608:+ | gene-YIR033W_EthanolRed | rna-NM_001179555.1_EthanolRed | cds-NP_012299.1_EthanolRed | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:417095-420436:+ | gene-YIR033W_FaliES1 | rna-NM_001179555.1_FaliES1 | cds-NP_012299.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000039.1:13661-17002:- | gene-YIR033W_JAY291 | rna-NM_001179555.1_JAY291 | cds-NP_012299.1_JAY291 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:421302-424643:+ | gene-YIR033W_MUCL30387 | rna-NM_001179555.1_MUCL30387 | cds-NP_012299.1_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:415918-419259:+ | gene-YIR033W_MUCL30388 | rna-NM_001179555.1_MUCL30388 | cds-NP_012299.1_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:415450-418791:+ | gene-YIR033W_MUCL39482 | rna-NM_001179555.1_MUCL39482 | cds-NP_012299.1_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:421762-425103:+ | gene-YIR033W_MUCL42920 | rna-NM_001179555.1_MUCL42920 | cds-NP_012299.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:416124-419465:+ | gene-YIR033W_NCIM3186 | rna-NM_001179555.1_NCIM3186 | cds-NP_012299.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:419214-422555:+ | gene-YIR033W_NCYC1407 | rna-NM_001179555.1_NCYC1407 | cds-NP_012299.1_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:410131-413472:+ | gene-YIR033W_PE2H3 | rna-NM_001179555.1_PE2H3 | cds-NP_012299.1_PE2H3 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:404837-408178:+ | gene-YIR033W_PE2H4 | rna-NM_001179555.1_PE2H4 | cds-NP_012299.1_PE2H4 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:416124-419465:+ | gene-YIR033W_S288C | rna-NM_001179555.1_S288C | cds-NP_012299.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000097.1:9381-12722:- | gene-YIR033W_SA1 | rna-NM_001179555.1_SA1 | cds-NP_012299.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:413960-417301:+ | gene-YIR033W_ThermosaccDry | rna-NM_001179555.1_ThermosaccDry | cds-NP_012299.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:411367-414708:+ | gene-YIR033W_VR1 | rna-NM_001179555.1_VR1 | cds-NP_012299.1_VR1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000020.1:23203-26544:+ | gene-YIR033W_ZTW1 | rna-NM_001179555.1_ZTW1 | cds-NP_012299.1_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:411649-414993:+ | gene-YIR033W_Sparadoxus | rna-NM_001179555.1_Sparadoxus | cds-NP_012299.1_Sparadoxus | 90.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |