MFM1 (YPL060W)


Gene profile

Gene name: MFM1
Reference locus (S288C): YPL060W
Gene biotype: protein_coding

Description: Mitochondrial inner membrane magnesium transporter; involved in maintenance of mitochondrial magnesium concentrations and membrane potential; indirectly affects splicing of group II introns; functionally and structurally related to Mrs2p; Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family

Top 10 interactors (score): ALR2 (0.922); ALR1 (0.908); MNR2 (0.885); RRG1 (0.769); MME1 (0.74); MRS3 (0.67); ATX2 (0.654); MRS4 (0.635); MDM38 (0.602); ZRT2 (0.579); MNP1 (0.573); YDL114W (0.571); CKB2 (0.565); UGA2 (0.563); CCC2 (0.532); FET4 (0.523); OLI1 (0.52); SMF3 (0.504); MRPL10 (0.497); ZRT1 (0.494)

Homologues (species, bitscore): MRS2 (Homo sapiens, 89.4); Mrs2 (Mus musculus, 100.5); MRS2 (Danio rerio, 94.4); mrs2 (Xenopus tropicalis, 91.3); MGT10 (Arabidopsis thaliana, 110.9)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:412247-413488:+ gene-YPL060W_AKU4011 rna-NM_001183874.1_AKU4011 cds-NP_015265.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000069.1:617927-619168:+ gene-YPL060W_BG1 rna-NM_001183874.1_BG1 cds-NP_015265.1_BG1 99.4 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:488576-489817:+ gene-YPL060W_Bruggeman rna-NM_001183874.1_Bruggeman cds-NP_015265.1_Bruggeman 99.5 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:528933-530174:+ gene-YPL060W_CAT1 rna-NM_001183874.1_CAT1 cds-NP_015265.1_CAT1 99.5 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:416320-417561:+ gene-YPL060W_CBS1585 rna-NM_001183874.1_CBS1585 cds-NP_015265.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:430876-432117:+ gene-YPL060W_CBS436 rna-NM_001183874.1_CBS436 cds-NP_015265.1_CBS436 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:420509-421750:+ gene-YPL060W_CBS6412 rna-NM_001183874.1_CBS6412 cds-NP_015265.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:412872-414113:+ gene-YPL060W_CBS6413 rna-NM_001183874.1_CBS6413 cds-NP_015265.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:434487-435728:+ gene-YPL060W_CENPK1137D rna-NM_001183874.1_CENPK1137D cds-NP_015265.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:410611-411852:+ gene-YPL060W_EthanolRed rna-NM_001183874.1_EthanolRed cds-NP_015265.1_EthanolRed 99.9 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:418441-419682:+ gene-YPL060W_FaliES1 rna-NM_001183874.1_FaliES1 cds-NP_015265.1_FaliES1 99.9 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000283.1:27049-28290:+ gene-YPL060W_JAY291 rna-NM_001183874.1_JAY291 cds-NP_015265.1_JAY291 99.6 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:429406-430647:+ gene-YPL060W_MUCL30387 rna-NM_001183874.1_MUCL30387 cds-NP_015265.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:428491-429732:+ gene-YPL060W_MUCL30388 rna-NM_001183874.1_MUCL30388 cds-NP_015265.1_MUCL30388 99.5 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:409649-410890:+ gene-YPL060W_MUCL39482 rna-NM_001183874.1_MUCL39482 cds-NP_015265.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:467512-468753:+ gene-YPL060W_MUCL42920 rna-NM_001183874.1_MUCL42920 cds-NP_015265.1_MUCL42920 99.5 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:434506-435747:+ gene-YPL060W_NCIM3186 rna-NM_001183874.1_NCIM3186 cds-NP_015265.1_NCIM3186 99.1 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:416932-418173:+ gene-YPL060W_NCYC1407 rna-NM_001183874.1_NCYC1407 cds-NP_015265.1_NCYC1407 99.9 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:423541-424782:+ gene-YPL060W_PE2H3 rna-NM_001183874.1_PE2H3 cds-NP_015265.1_PE2H3 99.6 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:423159-424400:+ gene-YPL060W_PE2H4 rna-NM_001183874.1_PE2H4 cds-NP_015265.1_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:434523-435764:+ gene-YPL060W_S288C rna-NM_001183874.1_S288C cds-NP_015265.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000057.1:56637-57878:+ gene-YPL060W_SA1 rna-NM_001183874.1_SA1 cds-NP_015265.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:418241-419482:+ gene-YPL060W_ThermosaccDry rna-NM_001183874.1_ThermosaccDry cds-NP_015265.1_ThermosaccDry 99.9 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:433249-434490:+ gene-YPL060W_VR1 rna-NM_001183874.1_VR1 cds-NP_015265.1_VR1 99.4 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:417550-418791:+ gene-YPL060W_ZTW1 rna-NM_001183874.1_ZTW1 cds-NP_015265.1_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:419254-420495:+ gene-YPL060W_Sparadoxus rna-NM_001183874.1_Sparadoxus cds-NP_015265.1_Sparadoxus 89.7 100.0 Verified 1 1 1 False True False False False

Additional files