Gene name: MET8
Reference locus (S288C): YBR213W
Gene biotype: protein_coding
Description: Siroheme biosynthesis protein MET8; Bifunctional dehydrogenase and ferrochelatase; involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis; Belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. MET8 subfamily
Top 10 interactors (score): MET1 (0.997); MET16 (0.979); MET10 (0.976); MET14 (0.945); MET5 (0.905); MET17 (0.878); MET22 (0.86); MET3 (0.858); MET28 (0.793); SUL2 (0.767); SAH1 (0.742); MET2 (0.711); ARO7 (0.705); STR3 (0.697); HEM12 (0.695); MET12 (0.619); NCP1 (0.611); CYS3 (0.605); HEM3 (0.601); HEM4 (0.578)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:634670-635494:+ | gene-YBR213W_AKU4011 | rna-NM_001178561.1_AKU4011 | cds-NP_009772.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000066.1:5591-6415:+ | gene-YBR213W_BG1 | rna-NM_001178561.1_BG1 | cds-NP_009772.1_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005504.1:635828-636652:+ | gene-YBR213W_Bruggeman | rna-NM_001178561.1_Bruggeman | cds-NP_009772.1_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:639030-639854:+ | gene-YBR213W_CAT1 | rna-NM_001178561.1_CAT1 | cds-NP_009772.1_CAT1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:626202-627026:+ | gene-YBR213W_CBS1585 | rna-NM_001178561.1_CBS1585 | cds-NP_009772.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:632629-633453:+ | gene-YBR213W_CBS436 | rna-NM_001178561.1_CBS436 | cds-NP_009772.1_CBS436 | 99.1 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:721179-722003:+ | gene-YBR213W_CBS6412 | rna-NM_001178561.1_CBS6412 | cds-NP_009772.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:632241-633065:+ | gene-YBR213W_CBS6413 | rna-NM_001178561.1_CBS6413 | cds-NP_009772.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:644114-644938:+ | gene-YBR213W_CENPK1137D | rna-NM_001178561.1_CENPK1137D | cds-NP_009772.1_CENPK1137D | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:757916-758740:+ | gene-YBR213W_EthanolRed | rna-NM_001178561.1_EthanolRed | cds-NP_009772.1_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:651023-651847:+ | gene-YBR213W_FaliES1 | rna-NM_001178561.1_FaliES1 | cds-NP_009772.1_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000326.1:5395-6219:+ | gene-YBR213W_JAY291 | rna-NM_001178561.1_JAY291 | cds-NP_009772.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:637841-638665:+ | gene-YBR213W_MUCL30387 | rna-NM_001178561.1_MUCL30387 | cds-NP_009772.1_MUCL30387 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:654919-655743:+ | gene-YBR213W_MUCL30388 | rna-NM_001178561.1_MUCL30388 | cds-NP_009772.1_MUCL30388 | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:624554-625378:+ | gene-YBR213W_MUCL39482 | rna-NM_001178561.1_MUCL39482 | cds-NP_009772.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:634037-634861:+ | gene-YBR213W_MUCL42920 | rna-NM_001178561.1_MUCL42920 | cds-NP_009772.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:650165-650989:+ | gene-YBR213W_NCIM3186 | rna-NM_001178561.1_NCIM3186 | cds-NP_009772.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:626416-627240:+ | gene-YBR213W_NCYC1407 | rna-NM_001178561.1_NCYC1407 | cds-NP_009772.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:649533-650357:+ | gene-YBR213W_PE2H3 | rna-NM_001178561.1_PE2H3 | cds-NP_009772.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:647209-648033:+ | gene-YBR213W_PE2H4 | rna-NM_001178561.1_PE2H4 | cds-NP_009772.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:650368-651192:+ | gene-YBR213W_S288C | rna-NM_001178561.1_S288C | cds-NP_009772.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000019.1:5488-6312:+ | gene-YBR213W_SA1 | rna-NM_001178561.1_SA1 | cds-NP_009772.1_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:650033-650857:+ | gene-YBR213W_ThermosaccDry | rna-NM_001178561.1_ThermosaccDry | cds-NP_009772.1_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:630204-631028:+ | gene-YBR213W_VR1 | rna-NM_001178561.1_VR1 | cds-NP_009772.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:622899-623723:+ | gene-YBR213W_ZTW1 | rna-NM_001178561.1_ZTW1 | cds-NP_009772.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:666866-667690:+ | gene-YBR213W_Sparadoxus | rna-NM_001178561.1_Sparadoxus | cds-NP_009772.1_Sparadoxus | 90.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |