Gene name: MET7
Reference locus (S288C): YOR241W
Gene biotype: protein_coding
Description: Folylpolyglutamate synthetase; catalyzes extension of the glutamate chains of the folate coenzymes, required for methionine synthesis and for maintenance of mitochondrial DNA; protein abundance increases in response to DNA replication stress
Top 10 interactors (score): DFR1 (0.989); MIS1 (0.986); SHM1 (0.98); ADE3 (0.978); SHM2 (0.97); CDC21 (0.96); FOL1 (0.945); RMA1 (0.899); FOL3 (0.885); MET12 (0.88); MET13 (0.877); FOL2 (0.851); MET6 (0.803); TRP3 (0.781); PRO2 (0.759); RNR1 (0.718); PUS7 (0.713); TRP5 (0.711); FAU1 (0.696); SEC59 (0.688)
Homologues (species, bitscore): FPGS (Homo sapiens, 323.6); Fpgs (Mus musculus, 323.2); fpgs (Danio rerio, 324.7); fpgs (Xenopus tropicalis, 318.2); CG2543 (Drosophila melanogaster, 248.4); F25B5.6 (Caenorhabditis elegans, 272.3); DFB (Arabidopsis thaliana, 268.1)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:777768-779413:+ | gene-YOR241W_AKU4011 | rna-NM_001183660.1_AKU4011 | cds-NP_014884.1_AKU4011 | 99.3 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000123.1:179807-181453:+ | gene-YOR241W_BG1 | rna-NM_001183660.1_BG1 | cds-NP_014884.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:763234-764880:+ | gene-YOR241W_Bruggeman | rna-NM_001183660.1_Bruggeman | cds-NP_014884.1_Bruggeman | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:763884-765531:+ | gene-YOR241W_CAT1 | rna-NM_001183660.1_CAT1 | cds-NP_014884.1_CAT1 | 99.8 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:760757-762402:+ | gene-YOR241W_CBS1585 | rna-NM_001183660.1_CBS1585 | cds-NP_014884.1_CBS1585 | 99.3 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:759451-761097:+ | gene-YOR241W_CBS436 | rna-NM_001183660.1_CBS436 | cds-NP_014884.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:757876-759521:+ | gene-YOR241W_CBS6412 | rna-NM_001183660.1_CBS6412 | cds-NP_014884.1_CBS6412 | 99.3 | 99.9 | Mismatch | 1 | 1 | 0 | False | False | False | True | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:766516-768161:+ | gene-YOR241W_CBS6413 | rna-NM_001183660.1_CBS6413 | cds-NP_014884.1_CBS6413 | 99.3 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:786758-788404:+ | gene-YOR241W_CENPK1137D | rna-NM_001183660.1_CENPK1137D | cds-NP_014884.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:753888-755533:+ | gene-YOR241W_EthanolRed | rna-NM_001183660.1_EthanolRed | cds-NP_014884.1_EthanolRed | 99.4 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:759287-760932:+ | gene-YOR241W_FaliES1 | rna-NM_001183660.1_FaliES1 | cds-NP_014884.1_FaliES1 | 99.4 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000381.1:65905-67552:- | gene-YOR241W_JAY291 | rna-NM_001183660.1_JAY291 | cds-NP_014884.1_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:767505-769151:+ | gene-YOR241W_MUCL30387 | rna-NM_001183660.1_MUCL30387 | cds-NP_014884.1_MUCL30387 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:774623-776269:+ | gene-YOR241W_MUCL30388 | rna-NM_001183660.1_MUCL30388 | cds-NP_014884.1_MUCL30388 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:768087-769732:+ | gene-YOR241W_MUCL39482 | rna-NM_001183660.1_MUCL39482 | cds-NP_014884.1_MUCL39482 | 99.3 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:777675-779321:+ | gene-YOR241W_MUCL42920 | rna-NM_001183660.1_MUCL42920 | cds-NP_014884.1_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:786884-788530:+ | gene-YOR241W_NCIM3186 | rna-NM_001183660.1_NCIM3186 | cds-NP_014884.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:768186-769831:+ | gene-YOR241W_NCYC1407 | rna-NM_001183660.1_NCYC1407 | cds-NP_014884.1_NCYC1407 | 99.3 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:767487-769133:+ | gene-YOR241W_PE2H3 | rna-NM_001183660.1_PE2H3 | cds-NP_014884.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:777864-779510:+ | gene-YOR241W_PE2H4 | rna-NM_001183660.1_PE2H4 | cds-NP_014884.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:786995-788641:+ | gene-YOR241W_S288C | rna-NM_001183660.1_S288C | cds-NP_014884.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000006.1:196988-198634:+ | gene-YOR241W_SA1 | rna-NM_001183660.1_SA1 | cds-NP_014884.1_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:758470-760115:+ | gene-YOR241W_ThermosaccDry | rna-NM_001183660.1_ThermosaccDry | cds-NP_014884.1_ThermosaccDry | 99.4 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:821927-823573:+ | gene-YOR241W_VR1 | rna-NM_001183660.1_VR1 | cds-NP_014884.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:491386-493031:+ | gene-YOR241W_ZTW1 | rna-NM_001183660.1_ZTW1 | cds-NP_014884.1_ZTW1 | 99.5 | 99.9 | Verified | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:764389-766029:+ | gene-YOR241W_Sparadoxus | rna-NM_001183660.1_Sparadoxus | cds-NP_014884.1_Sparadoxus | 89.9 | 99.5 | Unannotated | 1 | 1 | 0 | False | False | True | False | False |