Gene name: MET6
Reference locus (S288C): YER091C
Gene biotype: protein_coding
Description: 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Cobalamin-independent methionine synthase; involved in methionine biosynthesis and regeneration; requires a minimum of two glutamates on the methyltetrahydrofolate substrate, similar to bacterial metE homologs
Top 10 interactors (score): SAH1 (0.999); SAM2 (0.999); SAM1 (0.998); MET13 (0.985); MET17 (0.985); STR2 (0.982); STR3 (0.98); CYS4 (0.979); CYS3 (0.976); YML082W (0.966); YLL058W (0.956); HOM6 (0.954); ARO8 (0.95); MHT1 (0.944); MES1 (0.938); IRC7 (0.937); SHM2 (0.936); THR1 (0.925); MET2 (0.919); ILV1 (0.919)
Homologues (species, bitscore): ATMS1 (Arabidopsis thaliana, 695.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005299.1:333635-335938:- | gene-YER091C_AKU4011 | rna-NM_001178982.3_AKU4011 | cds-NP_011015.3_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000011.1:89896-92199:+ | gene-YER091C_BG1 | rna-NM_001178982.3_BG1 | cds-NP_011015.3_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005507.1:343196-345499:- | gene-YER091C_Bruggeman | rna-NM_001178982.3_Bruggeman | cds-NP_011015.3_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005523.1:337550-339853:- | gene-YER091C_CAT1 | rna-NM_001178982.3_CAT1 | cds-NP_011015.3_CAT1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005363.1:333500-335803:- | gene-YER091C_CBS1585 | rna-NM_001178982.3_CBS1585 | cds-NP_011015.3_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005347.1:335606-337909:- | gene-YER091C_CBS436 | rna-NM_001178982.3_CBS436 | cds-NP_011015.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005331.1:332956-335259:- | gene-YER091C_CBS6412 | rna-NM_001178982.3_CBS6412 | cds-NP_011015.3_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005315.1:338946-341249:- | gene-YER091C_CBS6413 | rna-NM_001178982.3_CBS6413 | cds-NP_011015.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001526.1:337773-340076:- | gene-YER091C_CENPK1137D | rna-NM_001178982.3_CENPK1137D | cds-NP_011015.3_CENPK1137D | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005475.1:333978-336281:- | gene-YER091C_EthanolRed | rna-NM_001178982.3_EthanolRed | cds-NP_011015.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005539.1:334423-336726:- | gene-YER091C_FaliES1 | rna-NM_001178982.3_FaliES1 | cds-NP_011015.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000153.1:49485-51788:- | gene-YER091C_JAY291 | rna-NM_001178982.3_JAY291 | cds-NP_011015.3_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005411.1:338591-340894:- | gene-YER091C_MUCL30387 | rna-NM_001178982.3_MUCL30387 | cds-NP_011015.3_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005443.1:334264-336567:- | gene-YER091C_MUCL30388 | rna-NM_001178982.3_MUCL30388 | cds-NP_011015.3_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005283.1:332524-334827:- | gene-YER091C_MUCL39482 | rna-NM_001178982.3_MUCL39482 | cds-NP_011015.3_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005427.1:339729-342032:- | gene-YER091C_MUCL42920 | rna-NM_001178982.3_MUCL42920 | cds-NP_011015.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011814.1:339863-342166:- | gene-YER091C_NCIM3186 | rna-NM_001178982.3_NCIM3186 | cds-NP_011015.3_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005267.1:337587-339890:- | gene-YER091C_NCYC1407 | rna-NM_001178982.3_NCYC1407 | cds-NP_011015.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994144.1:348239-350542:- | gene-YER091C_PE2H3 | rna-NM_001178982.3_PE2H3 | cds-NP_011015.3_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999876.1:338180-340483:- | gene-YER091C_PE2H4 | rna-NM_001178982.3_PE2H4 | cds-NP_011015.3_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001137.3:339864-342167:- | gene-YER091C_S288C | rna-NM_001178982.3_S288C | cds-NP_011015.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000023.1:49455-51758:- | gene-YER091C_SA1 | rna-NM_001178982.3_SA1 | cds-NP_011015.3_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005491.1:335220-337523:- | gene-YER091C_ThermosaccDry | rna-NM_001178982.3_ThermosaccDry | cds-NP_011015.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005459.1:335881-338184:- | gene-YER091C_VR1 | rna-NM_001178982.3_VR1 | cds-NP_011015.3_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000009.1:332382-334684:- | gene-YER091C_ZTW1 | rna-NM_001178982.3_ZTW1 | cds-NP_011015.3_ZTW1 | 99.9 | 99.9 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047491.1:335793-338096:- | gene-YER091C_Sparadoxus | rna-NM_001178982.3_Sparadoxus | cds-NP_011015.3_Sparadoxus | 93.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |