Gene name: MET32
Reference locus (S288C): YDR253C
Gene biotype: protein_coding
Description: Transcriptional regulator MET32; Zinc-finger DNA-binding transcription factor; involved in transcriptional regulation of the methionine biosynthetic genes; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; feedforward loop exists in the regulation of genes controlled by Met4p and Met32p; lack of such a loop for MET31 may account for the differential actions of Met32p and Met31p; MET32 has a paralog, MET31, that arose from the whole genome duplication
Top 10 interactors (score): CBF1 (0.988); MET4 (0.984); MET30 (0.965); MET28 (0.946); MET14 (0.905); MET16 (0.9); SUL2 (0.877); MET3 (0.876); MET2 (0.863); MET10 (0.849); GCN4 (0.843); MET1 (0.807); MET31 (0.802); MET17 (0.793); GSH1 (0.79); FHL1 (0.785); BAS1 (0.744); SFP1 (0.725); DAL80 (0.724); GLN3 (0.683)
Homologues (species, bitscore): ZNF132 (Homo sapiens, 62.4); Gm2004 (Mus musculus, 62.4); prdm9 (Danio rerio, 65.1); ENSXETP00000037770 (Xenopus tropicalis, 60.8); btd (Drosophila melanogaster, 63.2); mnm-2 (Caenorhabditis elegans, 58.9)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:920319-920894:- | gene-YDR253C_AKU4011 | rna-NM_001180561.1_AKU4011 | cds-NP_010539.1_AKU4011 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000080.1:204411-204986:+ | gene-YDR253C_BG1 | rna-NM_001180561.1_BG1 | cds-NP_010539.1_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:952648-953223:- | gene-YDR253C_Bruggeman | rna-NM_001180561.1_Bruggeman | cds-NP_010539.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:939933-940508:- | gene-YDR253C_CAT1 | rna-NM_001180561.1_CAT1 | cds-NP_010539.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:910668-911243:- | gene-YDR253C_CBS1585 | rna-NM_001180561.1_CBS1585 | cds-NP_010539.1_CBS1585 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:940227-940802:- | gene-YDR253C_CBS436 | rna-NM_001180561.1_CBS436 | cds-NP_010539.1_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:907428-908003:- | gene-YDR253C_CBS6412 | rna-NM_001180561.1_CBS6412 | cds-NP_010539.1_CBS6412 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:938522-939097:- | gene-YDR253C_CBS6413 | rna-NM_001180561.1_CBS6413 | cds-NP_010539.1_CBS6413 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:962915-963490:- | gene-YDR253C_CENPK1137D | rna-NM_001180561.1_CENPK1137D | cds-NP_010539.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:920987-921562:- | gene-YDR253C_EthanolRed | rna-NM_001180561.1_EthanolRed | cds-NP_010539.1_EthanolRed | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:929189-929764:- | gene-YDR253C_FaliES1 | rna-NM_001180561.1_FaliES1 | cds-NP_010539.1_FaliES1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000261.1:17723-18298:- | gene-YDR253C_JAY291 | rna-NM_001180561.1_JAY291 | cds-NP_010539.1_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:938546-939121:- | gene-YDR253C_MUCL30387 | rna-NM_001180561.1_MUCL30387 | cds-NP_010539.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:926576-927151:- | gene-YDR253C_MUCL30388 | rna-NM_001180561.1_MUCL30388 | cds-NP_010539.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:912073-912648:- | gene-YDR253C_MUCL39482 | rna-NM_001180561.1_MUCL39482 | cds-NP_010539.1_MUCL39482 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:851837-852412:- | gene-YDR253C_MUCL42920 | rna-NM_001180561.1_MUCL42920 | cds-NP_010539.1_MUCL42920 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:963913-964488:- | gene-YDR253C_NCIM3186 | rna-NM_001180561.1_NCIM3186 | cds-NP_010539.1_NCIM3186 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:915742-916317:- | gene-YDR253C_NCYC1407 | rna-NM_001180561.1_NCYC1407 | cds-NP_010539.1_NCYC1407 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:932000-932575:- | gene-YDR253C_PE2H3 | rna-NM_001180561.1_PE2H3 | cds-NP_010539.1_PE2H3 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:937277-937852:- | gene-YDR253C_PE2H4 | rna-NM_001180561.1_PE2H4 | cds-NP_010539.1_PE2H4 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:963990-964565:- | gene-YDR253C_S288C | rna-NM_001180561.1_S288C | cds-NP_010539.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000013.1:169837-170412:- | gene-YDR253C_SA1 | rna-NM_001180561.1_SA1 | cds-NP_010539.1_SA1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:927343-927918:- | gene-YDR253C_ThermosaccDry | rna-NM_001180561.1_ThermosaccDry | cds-NP_010539.1_ThermosaccDry | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:942600-943175:- | gene-YDR253C_VR1 | rna-NM_001180561.1_VR1 | cds-NP_010539.1_VR1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000007.1:190087-190662:- | gene-YDR253C_ZTW1 | rna-NM_001180561.1_ZTW1 | cds-NP_010539.1_ZTW1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:932753-933328:- | gene-YDR253C_Sparadoxus | rna-NM_001180561.1_Sparadoxus | cds-NP_010539.1_Sparadoxus | 92.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |