MET31 (YPL038W)


Gene profile

Gene name: MET31
Reference locus (S288C): YPL038W
Gene biotype: protein_coding

Description: Transcriptional regulator MET31; Zinc-finger DNA-binding transcription factor; targets strong transcriptional activator Met4p to promoters of sulfur metabolic genes; involved in transcriptional regulation of the methionine biosynthetic genes; feedforward loop controlling expression of MET32 and the lack of such a loop for MET31 may account for the differential actions of Met31p and Met32p; MET31 has a paralog, MET32, that arose from the whole genome duplication

Top 10 interactors (score): MET4 (0.993); MET28 (0.966); CBF1 (0.944); MET30 (0.892); GCN4 (0.882); MET14 (0.85); MET32 (0.802); MET3 (0.8); GSH1 (0.797); MET17 (0.793); DAL80 (0.782); BAS1 (0.765); MET16 (0.747); MET10 (0.735); YHR112C (0.726); MCM1 (0.718); GLN3 (0.686); RPN4 (0.685); FHL1 (0.672); SWI4 (0.656)

Homologues (species, bitscore): ZNF671 (Homo sapiens, 60.8); Ovol1 (Mus musculus, 58.2); si:ch211-119o8.6 (Danio rerio, 58.9); ENSXETP00000001440 (Xenopus tropicalis, 57.8); klu (Drosophila melanogaster, 55.5); ztf-16 (Caenorhabditis elegans, 54.7)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005310.1:452034-452567:+ gene-YPL038W_AKU4011 rna-NM_001183852.1_AKU4011 cds-NP_015287.1_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000091.1:444851-445384:- gene-YPL038W_BG1 rna-NM_001183852.1_BG1 cds-NP_015287.1_BG1 99.6 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005518.1:528975-529508:+ gene-YPL038W_Bruggeman rna-NM_001183852.1_Bruggeman cds-NP_015287.1_Bruggeman 99.6 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005534.1:568662-569195:+ gene-YPL038W_CAT1 rna-NM_001183852.1_CAT1 cds-NP_015287.1_CAT1 99.4 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005374.1:456102-456635:+ gene-YPL038W_CBS1585 rna-NM_001183852.1_CBS1585 cds-NP_015287.1_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005358.1:470220-470753:+ gene-YPL038W_CBS436 rna-NM_001183852.1_CBS436 cds-NP_015287.1_CBS436 99.6 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005342.1:460294-460827:+ gene-YPL038W_CBS6412 rna-NM_001183852.1_CBS6412 cds-NP_015287.1_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005326.1:452654-453187:+ gene-YPL038W_CBS6413 rna-NM_001183852.1_CBS6413 cds-NP_015287.1_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001537.1:480512-481045:+ gene-YPL038W_CENPK1137D rna-NM_001183852.1_CENPK1137D cds-NP_015287.1_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005486.1:450391-450924:+ gene-YPL038W_EthanolRed rna-NM_001183852.1_EthanolRed cds-NP_015287.1_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005550.1:458221-458754:+ gene-YPL038W_FaliES1 rna-NM_001183852.1_FaliES1 cds-NP_015287.1_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000283.1:66811-67344:+ gene-YPL038W_JAY291 rna-NM_001183852.1_JAY291 cds-NP_015287.1_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005422.1:469911-470444:+ gene-YPL038W_MUCL30387 rna-NM_001183852.1_MUCL30387 cds-NP_015287.1_MUCL30387 99.4 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005454.1:469052-469585:+ gene-YPL038W_MUCL30388 rna-NM_001183852.1_MUCL30388 cds-NP_015287.1_MUCL30388 99.4 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005294.1:449418-449951:+ gene-YPL038W_MUCL39482 rna-NM_001183852.1_MUCL39482 cds-NP_015287.1_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005438.1:508013-508546:+ gene-YPL038W_MUCL42920 rna-NM_001183852.1_MUCL42920 cds-NP_015287.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011825.1:480518-481051:+ gene-YPL038W_NCIM3186 rna-NM_001183852.1_NCIM3186 cds-NP_015287.1_NCIM3186 99.4 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005278.1:456698-457231:+ gene-YPL038W_NCYC1407 rna-NM_001183852.1_NCYC1407 cds-NP_015287.1_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994155.1:463305-463838:+ gene-YPL038W_PE2H3 rna-NM_001183852.1_PE2H3 cds-NP_015287.1_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999887.1:462920-463453:+ gene-YPL038W_PE2H4 rna-NM_001183852.1_PE2H4 cds-NP_015287.1_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001148.4:480535-481068:+ gene-YPL038W_S288C rna-NM_001183852.1_S288C cds-NP_015287.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000029.1:23376-23909:+ gene-YPL038W_SA1 rna-NM_001183852.1_SA1 cds-NP_015287.1_SA1 99.4 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005502.1:458020-458553:+ gene-YPL038W_ThermosaccDry rna-NM_001183852.1_ThermosaccDry cds-NP_015287.1_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005470.1:472899-473432:+ gene-YPL038W_VR1 rna-NM_001183852.1_VR1 cds-NP_015287.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000033.1:457322-457855:+ gene-YPL038W_ZTW1 rna-NM_001183852.1_ZTW1 cds-NP_015287.1_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047502.1:457310-457843:+ gene-YPL038W_Sparadoxus rna-NM_001183852.1_Sparadoxus cds-NP_015287.1_Sparadoxus 90.1 99.6 Verified 1 1 1 False True False False False

Additional files