Gene name: MET30
Reference locus (S288C): YIL046W
Gene biotype: protein_coding
Description: F-box protein containing five copies of the WD40 motif; controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus; dissociation of Met30p from SCF complex in response to cadmium stress is regulated by Cdc48p
Top 10 interactors (score): SKP1 (0.999); CDC53 (0.999); MET4 (0.995); HRT1 (0.992); GRR1 (0.98); CDC34 (0.966); MET32 (0.965); SWE1 (0.957); CDC4 (0.95); APC11 (0.922); APC9 (0.91); CDC16 (0.909); CDC27 (0.905); APC1 (0.905); MND2 (0.903); CDC23 (0.903); SLX5 (0.902); SLX8 (0.902); APC2 (0.901); DOC1 (0.9)
Homologues (species, bitscore): FBXW7 (Homo sapiens, 226.1); Fbxw7 (Mus musculus, 227.6); FBXW7 (Danio rerio, 235.0); fbxw7 (Xenopus tropicalis, 228.0); ago (Drosophila melanogaster, 203.0); lin-23 (Caenorhabditis elegans, 151.8); WDR5a (Arabidopsis thaliana, 114.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005303.1:265483-267405:+ | gene-YIL046W_AKU4011 | rna-NM_001179396.1_AKU4011 | cds-NP_012218.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000164.1:126906-128828:+ | gene-YIL046W_BG1 | rna-NM_001179396.1_BG1 | cds-NP_012218.1_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005511.1:271739-273661:+ | gene-YIL046W_Bruggeman | rna-NM_001179396.1_Bruggeman | cds-NP_012218.1_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005527.1:259641-261563:+ | gene-YIL046W_CAT1 | rna-NM_001179396.1_CAT1 | cds-NP_012218.1_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005367.1:265308-267230:+ | gene-YIL046W_CBS1585 | rna-NM_001179396.1_CBS1585 | cds-NP_012218.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005351.1:260615-262537:+ | gene-YIL046W_CBS436 | rna-NM_001179396.1_CBS436 | cds-NP_012218.1_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005335.1:261923-263845:+ | gene-YIL046W_CBS6412 | rna-NM_001179396.1_CBS6412 | cds-NP_012218.1_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005319.1:257474-259396:+ | gene-YIL046W_CBS6413 | rna-NM_001179396.1_CBS6413 | cds-NP_012218.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001530.1:260361-262283:+ | gene-YIL046W_CENPK1137D | rna-NM_001179396.1_CENPK1137D | cds-NP_012218.1_CENPK1137D | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005479.1:249397-251319:+ | gene-YIL046W_EthanolRed | rna-NM_001179396.1_EthanolRed | cds-NP_012218.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005543.1:266936-268858:+ | gene-YIL046W_FaliES1 | rna-NM_001179396.1_FaliES1 | cds-NP_012218.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000365.1:30025-31947:- | gene-YIL046W_JAY291 | rna-NM_001179396.1_JAY291 | cds-NP_012218.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005415.1:268589-270511:+ | gene-YIL046W_MUCL30387 | rna-NM_001179396.1_MUCL30387 | cds-NP_012218.1_MUCL30387 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005447.1:265192-267114:+ | gene-YIL046W_MUCL30388 | rna-NM_001179396.1_MUCL30388 | cds-NP_012218.1_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005287.1:266151-268073:+ | gene-YIL046W_MUCL39482 | rna-NM_001179396.1_MUCL39482 | cds-NP_012218.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005431.1:269282-271204:+ | gene-YIL046W_MUCL42920 | rna-NM_001179396.1_MUCL42920 | cds-NP_012218.1_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011818.1:268651-270573:+ | gene-YIL046W_NCIM3186 | rna-NM_001179396.1_NCIM3186 | cds-NP_012218.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005271.1:270424-272346:+ | gene-YIL046W_NCYC1407 | rna-NM_001179396.1_NCYC1407 | cds-NP_012218.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994148.1:263665-265587:+ | gene-YIL046W_PE2H3 | rna-NM_001179396.1_PE2H3 | cds-NP_012218.1_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999880.1:258374-260296:+ | gene-YIL046W_PE2H4 | rna-NM_001179396.1_PE2H4 | cds-NP_012218.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001141.2:268651-270573:+ | gene-YIL046W_S288C | rna-NM_001179396.1_S288C | cds-NP_012218.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000031.1:55597-57519:- | gene-YIL046W_SA1 | rna-NM_001179396.1_SA1 | cds-NP_012218.1_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005495.1:265605-267527:+ | gene-YIL046W_ThermosaccDry | rna-NM_001179396.1_ThermosaccDry | cds-NP_012218.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005463.1:262776-264698:+ | gene-YIL046W_VR1 | rna-NM_001179396.1_VR1 | cds-NP_012218.1_VR1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000019.1:239448-241370:+ | gene-YIL046W_ZTW1 | rna-NM_001179396.1_ZTW1 | cds-NP_012218.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047495.1:261573-263486:+ | gene-YIL046W_Sparadoxus | rna-NM_001179396.1_Sparadoxus | cds-NP_012218.1_Sparadoxus | 90.4 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |