Gene name: MET17
Reference locus (S288C): YLR303W
Gene biotype: protein_coding
Description: Bifunctional cysteine synthase/o-acetylhomoserine aminocarboxypropyltransferase met17; Homocysteine/cysteine synthase; O-acetyl homoserine-O-acetyl serine sulfhydrylase; required for Methionine and cysteine biosynthesis; Belongs to the trans-sulfuration enzymes family
Top 10 interactors (score): CYS4 (0.992); MET2 (0.99); MET10 (0.987); MET6 (0.985); MET5 (0.978); MCY1 (0.97); GSH1 (0.969); URA3 (0.957); SAH1 (0.947); STR3 (0.938); LYS2 (0.935); AAT1 (0.934); MET3 (0.932); CYS3 (0.93); STR2 (0.921); MET14 (0.92); AAT2 (0.917); LEU2 (0.917); HIS3 (0.913); YLL058W (0.912)
Homologues (species, bitscore): CTH (Homo sapiens, 201.8); Cth (Mus musculus, 209.5); cth (Danio rerio, 201.4); cth (Xenopus tropicalis, 201.8); Eip55E (Drosophila melanogaster, 191.4); cth-2 (Caenorhabditis elegans, 193.7); MTO1 (Arabidopsis thaliana, 191.4)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:681011-682345:+ | gene-YLR303W_AKU4011 | rna-NM_001182191.1_AKU4011 | cds-NP_013406.1_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000170.1:50302-51636:- | gene-YLR303W_BG1 | rna-NM_001182191.1_BG1 | cds-NP_013406.1_BG1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:716840-718174:+ | gene-YLR303W_Bruggeman | rna-NM_001182191.1_Bruggeman | cds-NP_013406.1_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:714750-716084:+ | gene-YLR303W_CAT1 | rna-NM_001182191.1_CAT1 | cds-NP_013406.1_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:715937-717271:+ | gene-YLR303W_CBS1585 | rna-NM_001182191.1_CBS1585 | cds-NP_013406.1_CBS1585 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:700531-701865:+ | gene-YLR303W_CBS436 | rna-NM_001182191.1_CBS436 | cds-NP_013406.1_CBS436 | 99.9 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:678577-679911:+ | gene-YLR303W_CBS6412 | rna-NM_001182191.1_CBS6412 | cds-NP_013406.1_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:716603-717937:+ | gene-YLR303W_CBS6413 | rna-NM_001182191.1_CBS6413 | cds-NP_013406.1_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:717155-718489:+ | gene-YLR303W_CENPK1137D | rna-NM_001182191.1_CENPK1137D | cds-NP_013406.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:674289-675623:+ | gene-YLR303W_EthanolRed | rna-NM_001182191.1_EthanolRed | cds-NP_013406.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:703489-704823:+ | gene-YLR303W_FaliES1 | rna-NM_001182191.1_FaliES1 | cds-NP_013406.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000359.1:957-2291:- | gene-YLR303W_JAY291 | rna-NM_001182191.1_JAY291 | cds-NP_013406.1_JAY291 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:716074-717408:+ | gene-YLR303W_MUCL30387 | rna-NM_001182191.1_MUCL30387 | cds-NP_013406.1_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:721657-722991:+ | gene-YLR303W_MUCL30388 | rna-NM_001182191.1_MUCL30388 | cds-NP_013406.1_MUCL30388 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:717167-718501:+ | gene-YLR303W_MUCL39482 | rna-NM_001182191.1_MUCL39482 | cds-NP_013406.1_MUCL39482 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:712323-713657:+ | gene-YLR303W_MUCL42920 | rna-NM_001182191.1_MUCL42920 | cds-NP_013406.1_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:732516-733850:+ | gene-YLR303W_NCIM3186 | rna-NM_001182191.1_NCIM3186 | cds-NP_013406.1_NCIM3186 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:726509-727843:+ | gene-YLR303W_NCYC1407 | rna-NM_001182191.1_NCYC1407 | cds-NP_013406.1_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:714298-715632:+ | gene-YLR303W_PE2H3 | rna-NM_001182191.1_PE2H3 | cds-NP_013406.1_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:714042-715376:+ | gene-YLR303W_PE2H4 | rna-NM_001182191.1_PE2H4 | cds-NP_013406.1_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:732542-733876:+ | gene-YLR303W_S288C | rna-NM_001182191.1_S288C | cds-NP_013406.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000039.1:50804-52138:- | gene-YLR303W_SA1 | rna-NM_001182191.1_SA1 | cds-NP_013406.1_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:705383-706717:+ | gene-YLR303W_ThermosaccDry | rna-NM_001182191.1_ThermosaccDry | cds-NP_013406.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:717268-718602:+ | gene-YLR303W_VR1 | rna-NM_001182191.1_VR1 | cds-NP_013406.1_VR1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:43809-45143:+ | gene-YLR303W_ZTW1 | rna-NM_001182191.1_ZTW1 | cds-NP_013406.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:691422-692756:+ | gene-YLR303W_Sparadoxus | rna-NM_001182191.1_Sparadoxus | cds-NP_013406.1_Sparadoxus | 93.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |