Gene name: MET13
Reference locus (S288C): YGL125W
Gene biotype: protein_coding
Description: Methylenetetrahydrofolate reductase (nad(p)h) met13; Major isozyme of methylenetetrahydrofolate reductase; catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway
Top 10 interactors (score): ADE3 (0.987); MET12 (0.987); MET6 (0.985); GCV1 (0.985); GCV2 (0.979); SHM1 (0.977); MTD1 (0.975); MIS1 (0.972); SHM2 (0.97); GCV3 (0.968); CDC21 (0.967); LPD1 (0.925); STR3 (0.893); SAM2 (0.89); MET7 (0.877); MET10 (0.859); FOL3 (0.855); ARG5,6 (0.854); SAM1 (0.833); SAH1 (0.807)
Homologues (species, bitscore): MTHFR (Homo sapiens, 461.8); Mthfr (Mus musculus, 452.6); mthfr (Danio rerio, 448.0); mthfr (Xenopus tropicalis, 413.3); CG7560 (Drosophila melanogaster, 92.0); mthf-1 (Caenorhabditis elegans, 389.8); MTHFR2 (Arabidopsis thaliana, 483.0)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:275335-277137:+ | gene-YGL125W_AKU4011 | rna-NM_001180990.1_AKU4011 | cds-NP_011390.2_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:128048-129850:- | gene-YGL125W_BG1 | rna-NM_001180990.1_BG1 | cds-NP_011390.2_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:278036-279838:+ | gene-YGL125W_Bruggeman | rna-NM_001180990.1_Bruggeman | cds-NP_011390.2_Bruggeman | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:273617-275419:+ | gene-YGL125W_CAT1 | rna-NM_001180990.1_CAT1 | cds-NP_011390.2_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:278664-280466:+ | gene-YGL125W_CBS1585 | rna-NM_001180990.1_CBS1585 | cds-NP_011390.2_CBS1585 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:273567-275369:+ | gene-YGL125W_CBS436 | rna-NM_001180990.1_CBS436 | cds-NP_011390.2_CBS436 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:264301-266103:+ | gene-YGL125W_CBS6412 | rna-NM_001180990.1_CBS6412 | cds-NP_011390.2_CBS6412 | 99.3 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:273521-275323:+ | gene-YGL125W_CBS6413 | rna-NM_001180990.1_CBS6413 | cds-NP_011390.2_CBS6413 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:272779-274581:+ | gene-YGL125W_CENPK1137D | rna-NM_001180990.1_CENPK1137D | cds-NP_011390.2_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:265047-266849:+ | gene-YGL125W_EthanolRed | rna-NM_001180990.1_EthanolRed | cds-NP_011390.2_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:267003-268805:+ | gene-YGL125W_FaliES1 | rna-NM_001180990.1_FaliES1 | cds-NP_011390.2_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000408.1:390-2192:- | gene-YGL125W_JAY291 | rna-NM_001180990.1_JAY291 | cds-NP_011390.2_JAY291 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:275006-276808:+ | gene-YGL125W_MUCL30387 | rna-NM_001180990.1_MUCL30387 | cds-NP_011390.2_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:278124-279926:+ | gene-YGL125W_MUCL30388 | rna-NM_001180990.1_MUCL30388 | cds-NP_011390.2_MUCL30388 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:275748-277550:+ | gene-YGL125W_MUCL39482 | rna-NM_001180990.1_MUCL39482 | cds-NP_011390.2_MUCL39482 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:278998-280800:+ | gene-YGL125W_MUCL42920 | rna-NM_001180990.1_MUCL42920 | cds-NP_011390.2_MUCL42920 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:272520-274322:+ | gene-YGL125W_NCIM3186 | rna-NM_001180990.1_NCIM3186 | cds-NP_011390.2_NCIM3186 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:267238-269040:+ | gene-YGL125W_NCYC1407 | rna-NM_001180990.1_NCYC1407 | cds-NP_011390.2_NCYC1407 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:268624-270426:+ | gene-YGL125W_PE2H3 | rna-NM_001180990.1_PE2H3 | cds-NP_011390.2_PE2H3 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:273622-275424:+ | gene-YGL125W_PE2H4 | rna-NM_001180990.1_PE2H4 | cds-NP_011390.2_PE2H4 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:272520-274322:+ | gene-YGL125W_S288C | rna-NM_001180990.1_S288C | cds-NP_011390.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000064.1:17401-19203:+ | gene-YGL125W_SA1 | rna-NM_001180990.1_SA1 | cds-NP_011390.2_SA1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:267232-269034:+ | gene-YGL125W_ThermosaccDry | rna-NM_001180990.1_ThermosaccDry | cds-NP_011390.2_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:377354-379156:+ | gene-YGL125W_VR1 | rna-NM_001180990.1_VR1 | cds-NP_011390.2_VR1 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:264808-266610:+ | gene-YGL125W_ZTW1 | rna-NM_001180990.1_ZTW1 | cds-NP_011390.2_ZTW1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:270830-272632:+ | gene-YGL125W_Sparadoxus | rna-NM_001180990.1_Sparadoxus | cds-NP_011390.2_Sparadoxus | 91.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |