MET1 (YKR069W)


Gene profile

Gene name: MET1
Reference locus (S288C): YKR069W
Gene biotype: protein_coding

Description: Uroporphyrinogen-III C-methyltransferase; S-adenosyl-L-methionine uroporphyrinogen III transmethylase; involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis

Top 10 interactors (score): MET8 (0.997); MET10 (0.995); MET16 (0.983); MET5 (0.98); HEM12 (0.97); MET3 (0.964); HEM4 (0.96); MET14 (0.96); SUL2 (0.948); HEM3 (0.941); STR3 (0.925); MET2 (0.907); SSU1 (0.903); FZF1 (0.9); MET28 (0.877); HEM2 (0.833); MET17 (0.827); MET22 (0.808); MET32 (0.807); CYS3 (0.724)

Homologues (species, bitscore): UPM1 (Arabidopsis thaliana, 145.2)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005305.1:557657-559438:+ gene-YKR069W_AKU4011 rna-NM_001179859.3_AKU4011 cds-NP_012995.3_AKU4011 99.9 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000113.1:84838-86619:- gene-YKR069W_BG1 rna-NM_001179859.3_BG1 cds-NP_012995.3_BG1 99.2 100.0 Unannotated 1 1 0 False False False False True
Bruggeman GCA_001738585.1 Bread Not Applicable CM005513.1:579096-580877:+ gene-YKR069W_Bruggeman rna-NM_001179859.3_Bruggeman cds-NP_012995.3_Bruggeman 99.3 100.0 Unannotated 1 1 0 False False False False True
CAT1 GCA_001738705.1 Bioethanol South America CM005529.1:575503-577284:+ gene-YKR069W_CAT1 rna-NM_001179859.3_CAT1 cds-NP_012995.3_CAT1 99.2 100.0 Unannotated 1 1 0 False False False False True
CBS1585 GCA_001738375.1 Sake Asia CM005369.1:570150-571931:+ gene-YKR069W_CBS1585 rna-NM_001179859.3_CBS1585 cds-NP_012995.3_CBS1585 99.8 100.0 Unannotated 1 1 0 False False False False True
CBS436 GCA_001738355.1 Sake Asia CM005353.1:568479-570260:+ gene-YKR069W_CBS436 rna-NM_001179859.3_CBS436 cds-NP_012995.3_CBS436 99.3 100.0 Unannotated 1 1 0 False False False False True
CBS6412 GCA_001738345.1 Sake Asia CM005337.1:553438-555219:+ gene-YKR069W_CBS6412 rna-NM_001179859.3_CBS6412 cds-NP_012995.3_CBS6412 99.9 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005321.1:569968-571749:+ gene-YKR069W_CBS6413 rna-NM_001179859.3_CBS6413 cds-NP_012995.3_CBS6413 99.9 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001532.1:571279-573060:+ gene-YKR069W_CENPK1137D rna-NM_001179859.3_CENPK1137D cds-NP_012995.3_CENPK1137D 99.3 100.0 Unannotated 1 1 0 False False False False True
EthanolRed GCA_001738615.1 Bioethanol Asia CM005481.1:566967-568748:+ gene-YKR069W_EthanolRed rna-NM_001179859.3_EthanolRed cds-NP_012995.3_EthanolRed 99.9 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005545.1:570867-572648:+ gene-YKR069W_FaliES1 rna-NM_001179859.3_FaliES1 cds-NP_012995.3_FaliES1 99.9 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000410.1:5590-7370:- gene-YKR069W_JAY291 rna-NM_001179859.3_JAY291 cds-NP_012995.3_JAY291 99.9 99.9 Unannotated 1 1 0 False False False True False
MUCL30387 GCA_001738515.1 Bread Europe CM005417.1:579480-581261:+ gene-YKR069W_MUCL30387 rna-NM_001179859.3_MUCL30387 cds-NP_012995.3_MUCL30387 99.3 100.0 Unannotated 1 1 0 False False False False True
MUCL30388 GCA_001738495.1 Bread Europe CM005449.1:574080-575861:+ gene-YKR069W_MUCL30388 rna-NM_001179859.3_MUCL30388 cds-NP_012995.3_MUCL30388 99.6 100.0 Unannotated 1 1 0 False False False False True
MUCL39482 GCA_001738235.1 Sake Asia CM005289.1:568979-570760:+ gene-YKR069W_MUCL39482 rna-NM_001179859.3_MUCL39482 cds-NP_012995.3_MUCL39482 99.4 100.0 Unannotated 1 1 0 False False False False True
MUCL42920 GCA_001738485.1 Bread Europe CM005433.1:575003-576784:+ gene-YKR069W_MUCL42920 rna-NM_001179859.3_MUCL42920 cds-NP_012995.3_MUCL42920 99.3 100.0 Unannotated 1 1 0 False False False False True
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011820.1:571601-573382:+ gene-YKR069W_NCIM3186 rna-NM_001179859.3_NCIM3186 cds-NP_012995.3_NCIM3186 99.2 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005273.1:569400-571181:+ gene-YKR069W_NCYC1407 rna-NM_001179859.3_NCYC1407 cds-NP_012995.3_NCYC1407 99.9 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994150.1:594556-596337:+ gene-YKR069W_PE2H3 rna-NM_001179859.3_PE2H3 cds-NP_012995.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999882.1:578941-580722:+ gene-YKR069W_PE2H4 rna-NM_001179859.3_PE2H4 cds-NP_012995.3_PE2H4 99.3 100.0 Unannotated 1 1 0 False False False False True
S288C GCF_000146045.2 Laboratory Not applicable NC_001143.9:571612-573393:+ gene-YKR069W_S288C rna-NM_001179859.3_S288C cds-NP_012995.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000029.1:108451-110232:- gene-YKR069W_SA1 rna-NM_001179859.3_SA1 cds-NP_012995.3_SA1 99.7 100.0 Unannotated 1 1 0 False False False False True
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005497.1:570106-571887:+ gene-YKR069W_ThermosaccDry rna-NM_001179859.3_ThermosaccDry cds-NP_012995.3_ThermosaccDry 99.9 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005465.1:569866-571647:+ gene-YKR069W_VR1 rna-NM_001179859.3_VR1 cds-NP_012995.3_VR1 99.8 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000022.1:567594-569375:+ gene-YKR069W_ZTW1 rna-NM_001179859.3_ZTW1 cds-NP_012995.3_ZTW1 99.9 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047497.1:592991-594769:+ gene-YKR069W_Sparadoxus rna-NM_001179859.3_Sparadoxus cds-NP_012995.3_Sparadoxus 89.9 99.7 Unannotated 1 1 0 False False False False True

Additional files