Gene name: MES1
Reference locus (S288C): YGR264C
Gene biotype: protein_coding
Description: Methionine--tRNA ligase, cytoplasmic; Methionyl-tRNA synthetase; forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs; mutations in human ortholog MARS are associated with pediatric pulmonary alveolar proteinosis
Top 10 interactors (score): ILS1 (0.999); CDC60 (0.999); GLN4 (0.999); GUS1 (0.999); YHR020W (0.999); ARC1 (0.999); KRS1 (0.999); DPS1 (0.995); YDR341C (0.992); NAM2 (0.986); TYS1 (0.986); THS1 (0.984); ALA1 (0.982); SES1 (0.976); WRS1 (0.969); MSK1 (0.967); MSE1 (0.942); HTS1 (0.941); MET6 (0.938); FMT1 (0.937)
Homologues (species, bitscore): MARS (Homo sapiens, 634.8); Mars (Mus musculus, 635.6); mars (Danio rerio, 630.6); mars (Xenopus tropicalis, 570.9); CG15100 (Drosophila melanogaster, 617.5); mars-1 (Caenorhabditis elegans, 609.4); AT4G13780 (Arabidopsis thaliana, 636.3)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:985036-987291:- | gene-YGR264C_AKU4011 | rna-NM_001181393.3_AKU4011 | cds-NP_011780.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000021.1:265033-267288:- | gene-YGR264C_BG1 | rna-NM_001181393.3_BG1 | cds-NP_011780.3_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:993546-995801:- | gene-YGR264C_Bruggeman | rna-NM_001181393.3_Bruggeman | cds-NP_011780.3_Bruggeman | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:992739-994994:- | gene-YGR264C_CAT1 | rna-NM_001181393.3_CAT1 | cds-NP_011780.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:987906-990161:- | gene-YGR264C_CBS1585 | rna-NM_001181393.3_CBS1585 | cds-NP_011780.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:991526-993781:- | gene-YGR264C_CBS436 | rna-NM_001181393.3_CBS436 | cds-NP_011780.3_CBS436 | 100.0 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:978796-981051:- | gene-YGR264C_CBS6412 | rna-NM_001181393.3_CBS6412 | cds-NP_011780.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:984851-987106:- | gene-YGR264C_CBS6413 | rna-NM_001181393.3_CBS6413 | cds-NP_011780.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:1019270-1021525:- | gene-YGR264C_CENPK1137D | rna-NM_001181393.3_CENPK1137D | cds-NP_011780.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:972876-975131:- | gene-YGR264C_EthanolRed | rna-NM_001181393.3_EthanolRed | cds-NP_011780.3_EthanolRed | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:977682-979937:- | gene-YGR264C_FaliES1 | rna-NM_001181393.3_FaliES1 | cds-NP_011780.3_FaliES1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000076.1:50373-52628:+ | gene-YGR264C_JAY291 | rna-NM_001181393.3_JAY291 | cds-NP_011780.3_JAY291 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:991287-993542:- | gene-YGR264C_MUCL30387 | rna-NM_001181393.3_MUCL30387 | cds-NP_011780.3_MUCL30387 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:989419-991674:- | gene-YGR264C_MUCL30388 | rna-NM_001181393.3_MUCL30388 | cds-NP_011780.3_MUCL30388 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:983012-985267:- | gene-YGR264C_MUCL39482 | rna-NM_001181393.3_MUCL39482 | cds-NP_011780.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:1000874-1003129:- | gene-YGR264C_MUCL42920 | rna-NM_001181393.3_MUCL42920 | cds-NP_011780.3_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:1019598-1021853:- | gene-YGR264C_NCIM3186 | rna-NM_001181393.3_NCIM3186 | cds-NP_011780.3_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:978641-980896:- | gene-YGR264C_NCYC1407 | rna-NM_001181393.3_NCYC1407 | cds-NP_011780.3_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:1003826-1006081:- | gene-YGR264C_PE2H3 | rna-NM_001181393.3_PE2H3 | cds-NP_011780.3_PE2H3 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:1008665-1010920:- | gene-YGR264C_PE2H4 | rna-NM_001181393.3_PE2H4 | cds-NP_011780.3_PE2H4 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:1019598-1021853:- | gene-YGR264C_S288C | rna-NM_001181393.3_S288C | cds-NP_011780.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000063.1:17817-20072:- | gene-YGR264C_SA1 | rna-NM_001181393.3_SA1 | cds-NP_011780.3_SA1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:998202-1000457:- | gene-YGR264C_ThermosaccDry | rna-NM_001181393.3_ThermosaccDry | cds-NP_011780.3_ThermosaccDry | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:1103983-1106238:- | gene-YGR264C_VR1 | rna-NM_001181393.3_VR1 | cds-NP_011780.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000016.1:299615-301870:- | gene-YGR264C_ZTW1 | rna-NM_001181393.3_ZTW1 | cds-NP_011780.3_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:990238-992493:- | gene-YGR264C_Sparadoxus | rna-NM_001181393.3_Sparadoxus | cds-NP_011780.3_Sparadoxus | 91.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |