MEP1 (YGR121C)


Gene profile

Gene name: MEP1
Reference locus (S288C): YGR121C
Gene biotype: protein_coding

Description: Ammonium transporter MEP1; Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation; human homolog RHCG complements yeast null mutant; mutations in human homolog RHCG implicated in metabolic acidosis; MEP1 has a paralog, MEP3, that arose from the whole genome duplication

Top 10 interactors (score): MEP3 (0.999); MEP2 (0.999); GLN1 (0.91); GAP1 (0.888); NPR1 (0.822); DIP5 (0.82); DAL80 (0.81); GLN3 (0.787); DUR3 (0.776); GDH1 (0.753); PAR32 (0.747); GAT1 (0.734); SSY1 (0.703); YIL028W (0.692); PUT4 (0.692); GLT1 (0.69); AGP1 (0.679); GZF3 (0.677); GPA2 (0.672); GNP1 (0.667)

Homologues (species, bitscore): rhcga (Danio rerio, 51.6); CG6499 (Drosophila melanogaster, 111.3); amt-1 (Caenorhabditis elegans, 129.4); AMT2 (Arabidopsis thaliana, 156.0)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005301.1:710769-712247:- gene-YGR121C_AKU4011 rna-NM_001181250.3_AKU4011 cds-NP_011636.3_AKU4011 99.3 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000008.1:3198-4676:+ gene-YGR121C_BG1 rna-NM_001181250.3_BG1 cds-NP_011636.3_BG1 100.0 100.0 Verified 1 1 1 True True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005509.1:712434-713912:- gene-YGR121C_Bruggeman rna-NM_001181250.3_Bruggeman cds-NP_011636.3_Bruggeman 99.6 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005525.1:711163-712641:- gene-YGR121C_CAT1 rna-NM_001181250.3_CAT1 cds-NP_011636.3_CAT1 100.0 100.0 Verified 1 1 1 True True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005365.1:711758-713236:- gene-YGR121C_CBS1585 rna-NM_001181250.3_CBS1585 cds-NP_011636.3_CBS1585 99.4 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005349.1:713381-714859:- gene-YGR121C_CBS436 rna-NM_001181250.3_CBS436 cds-NP_011636.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005333.1:703427-704905:- gene-YGR121C_CBS6412 rna-NM_001181250.3_CBS6412 cds-NP_011636.3_CBS6412 99.3 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005317.1:708361-709839:- gene-YGR121C_CBS6413 rna-NM_001181250.3_CBS6413 cds-NP_011636.3_CBS6413 99.3 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001528.1:731167-732645:- gene-YGR121C_CENPK1137D rna-NM_001181250.3_CENPK1137D cds-NP_011636.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005477.1:697801-699279:- gene-YGR121C_EthanolRed rna-NM_001181250.3_EthanolRed cds-NP_011636.3_EthanolRed 99.4 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005541.1:701661-703139:- gene-YGR121C_FaliES1 rna-NM_001181250.3_FaliES1 cds-NP_011636.3_FaliES1 99.4 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000223.1:420-1898:- gene-YGR121C_JAY291 rna-NM_001181250.3_JAY291 cds-NP_011636.3_JAY291 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005413.1:711858-713336:- gene-YGR121C_MUCL30387 rna-NM_001181250.3_MUCL30387 cds-NP_011636.3_MUCL30387 99.6 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005445.1:712248-713726:- gene-YGR121C_MUCL30388 rna-NM_001181250.3_MUCL30388 cds-NP_011636.3_MUCL30388 99.6 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005285.1:707485-708963:- gene-YGR121C_MUCL39482 rna-NM_001181250.3_MUCL39482 cds-NP_011636.3_MUCL39482 99.4 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005429.1:717258-718736:- gene-YGR121C_MUCL42920 rna-NM_001181250.3_MUCL42920 cds-NP_011636.3_MUCL42920 99.6 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011816.1:731449-732927:- gene-YGR121C_NCIM3186 rna-NM_001181250.3_NCIM3186 cds-NP_011636.3_NCIM3186 99.6 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005269.1:702178-703656:- gene-YGR121C_NCYC1407 rna-NM_001181250.3_NCYC1407 cds-NP_011636.3_NCYC1407 99.3 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994146.1:721679-723157:- gene-YGR121C_PE2H3 rna-NM_001181250.3_PE2H3 cds-NP_011636.3_PE2H3 100.0 100.0 Verified 1 1 1 True True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999878.1:726797-728275:- gene-YGR121C_PE2H4 rna-NM_001181250.3_PE2H4 cds-NP_011636.3_PE2H4 100.0 100.0 Verified 1 1 1 True True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001139.9:731449-732927:- gene-YGR121C_S288C rna-NM_001181250.3_S288C cds-NP_011636.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000015.1:152785-154263:- gene-YGR121C_SA1 rna-NM_001181250.3_SA1 cds-NP_011636.3_SA1 99.5 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005493.1:722289-723767:- gene-YGR121C_ThermosaccDry rna-NM_001181250.3_ThermosaccDry cds-NP_011636.3_ThermosaccDry 99.5 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005461.1:824721-826199:- gene-YGR121C_VR1 rna-NM_001181250.3_VR1 cds-NP_011636.3_VR1 99.9 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000016.1:24435-25913:- gene-YGR121C_ZTW1 rna-NM_001181250.3_ZTW1 cds-NP_011636.3_ZTW1 99.3 100.0 Verified 1 1 1 False True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047493.1:711903-713381:- gene-YGR121C_Sparadoxus rna-NM_001181250.3_Sparadoxus cds-NP_011636.3_Sparadoxus 90.1 100.0 Verified 1 1 1 False True False False False

Additional files