Gene name: MEK1
Reference locus (S288C): YOR351C
Gene biotype: protein_coding
Description: Meiosis-specific serine/threonine protein kinase; functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids; stabilizes Hop1-Thr318 phosphorylation to promote interhomolog recombination and checkpoint responses during meiosis
Top 10 interactors (score): HOP1 (0.997); RED1 (0.996); DMC1 (0.971); SPO11 (0.935); RAD54 (0.931); ZIP1 (0.93); HOP2 (0.921); NDT80 (0.893); PCH2 (0.857); SPO13 (0.853); MEC1 (0.828); REC8 (0.814); TEL1 (0.791); RAD51 (0.708); MEI4 (0.691); ZIP2 (0.672); NDJ1 (0.672); CDC28 (0.671); SEC4 (0.653); REC114 (0.651)
Homologues (species, bitscore): PNCK (Homo sapiens, 156.0); Camk1g (Mus musculus, 155.2); camk1da (Danio rerio, 160.2); camk1g (Xenopus tropicalis, 162.2); CaMKI (Drosophila melanogaster, 160.6); cmk-1 (Caenorhabditis elegans, 154.5); CPK16 (Arabidopsis thaliana, 139.8)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:981604-983097:- | gene-YOR351C_AKU4011 | rna-NM_001183771.3_AKU4011 | cds-NP_014996.3_AKU4011 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000078.1:18785-20278:- | gene-YOR351C_BG1 | rna-NM_001183771.3_BG1 | cds-NP_014996.3_BG1 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:966420-967913:- | gene-YOR351C_Bruggeman | rna-NM_001183771.3_Bruggeman | cds-NP_014996.3_Bruggeman | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:966251-967744:- | gene-YOR351C_CAT1 | rna-NM_001183771.3_CAT1 | cds-NP_014996.3_CAT1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:966013-967506:- | gene-YOR351C_CBS1585 | rna-NM_001183771.3_CBS1585 | cds-NP_014996.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:960827-962320:- | gene-YOR351C_CBS436 | rna-NM_001183771.3_CBS436 | cds-NP_014996.3_CBS436 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005339.1:195314-196807:- | gene-YOR351C_CBS6412 | rna-NM_001183771.3_CBS6412 | cds-NP_014996.3_CBS6412 | 99.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:970286-971779:- | gene-YOR351C_CBS6413 | rna-NM_001183771.3_CBS6413 | cds-NP_014996.3_CBS6413 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:994806-996299:- | gene-YOR351C_CENPK1137D | rna-NM_001183771.3_CENPK1137D | cds-NP_014996.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:210309-211802:- | gene-YOR351C_EthanolRed | rna-NM_001183771.3_EthanolRed | cds-NP_014996.3_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:963138-964631:- | gene-YOR351C_FaliES1 | rna-NM_001183771.3_FaliES1 | cds-NP_014996.3_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000078.1:41035-42528:+ | gene-YOR351C_JAY291 | rna-NM_001183771.3_JAY291 | cds-NP_014996.3_JAY291 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:975749-977242:- | gene-YOR351C_MUCL30387 | rna-NM_001183771.3_MUCL30387 | cds-NP_014996.3_MUCL30387 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:983765-985258:- | gene-YOR351C_MUCL30388 | rna-NM_001183771.3_MUCL30388 | cds-NP_014996.3_MUCL30388 | 99.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:972548-974041:- | gene-YOR351C_MUCL39482 | rna-NM_001183771.3_MUCL39482 | cds-NP_014996.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:980152-981645:- | gene-YOR351C_MUCL42920 | rna-NM_001183771.3_MUCL42920 | cds-NP_014996.3_MUCL42920 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:994907-996400:- | gene-YOR351C_NCIM3186 | rna-NM_001183771.3_NCIM3186 | cds-NP_014996.3_NCIM3186 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:973558-975051:- | gene-YOR351C_NCYC1407 | rna-NM_001183771.3_NCYC1407 | cds-NP_014996.3_NCYC1407 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:968815-970308:- | gene-YOR351C_PE2H3 | rna-NM_001183771.3_PE2H3 | cds-NP_014996.3_PE2H3 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:985167-986660:- | gene-YOR351C_PE2H4 | rna-NM_001183771.3_PE2H4 | cds-NP_014996.3_PE2H4 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:995018-996511:- | gene-YOR351C_S288C | rna-NM_001183771.3_S288C | cds-NP_014996.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000016.1:99473-100966:- | gene-YOR351C_SA1 | rna-NM_001183771.3_SA1 | cds-NP_014996.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:962308-963801:- | gene-YOR351C_ThermosaccDry | rna-NM_001183771.3_ThermosaccDry | cds-NP_014996.3_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:1023567-1025060:- | gene-YOR351C_VR1 | rna-NM_001183771.3_VR1 | cds-NP_014996.3_VR1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000032.1:695039-696532:- | gene-YOR351C_ZTW1 | rna-NM_001183771.3_ZTW1 | cds-NP_014996.3_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:968576-970069:- | gene-YOR351C_Sparadoxus | rna-NM_001183771.3_Sparadoxus | cds-NP_014996.3_Sparadoxus | 89.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |