Gene name: MED8
Reference locus (S288C): YBR193C
Gene biotype: protein_coding
Description: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
Top 10 interactors (score): MED6 (0.999); SRB7 (0.999); NUT2 (0.999); SRB5 (0.999); MED11 (0.999); RGR1 (0.999); SRB4 (0.999); MED7 (0.999); SRB2 (0.999); SOH1 (0.999); SRB6 (0.999); ROX3 (0.998); MED4 (0.998); CSE2 (0.998); GAL11 (0.996); RPB4 (0.996); SIN4 (0.996); MED1 (0.996); MED2 (0.995); PGD1 (0.987)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005296.1:592451-593122:- | gene-YBR193C_AKU4011 | rna-NM_001178541.3_AKU4011 | cds-NP_009752.3_AKU4011 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000179.1:582455-583126:- | gene-YBR193C_BG1 | rna-NM_001178541.3_BG1 | cds-NP_009752.3_BG1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005518.1:398310-398981:- | gene-YBR193C_Bruggeman | rna-NM_001178541.3_Bruggeman | cds-NP_009752.3_Bruggeman | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005520.1:597716-598387:- | gene-YBR193C_CAT1 | rna-NM_001178541.3_CAT1 | cds-NP_009752.3_CAT1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005360.1:584232-584903:- | gene-YBR193C_CBS1585 | rna-NM_001178541.3_CBS1585 | cds-NP_009752.3_CBS1585 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005344.1:591781-592452:- | gene-YBR193C_CBS436 | rna-NM_001178541.3_CBS436 | cds-NP_009752.3_CBS436 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005328.1:680841-681512:- | gene-YBR193C_CBS6412 | rna-NM_001178541.3_CBS6412 | cds-NP_009752.3_CBS6412 | 99.7 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005312.1:590038-590709:- | gene-YBR193C_CBS6413 | rna-NM_001178541.3_CBS6413 | cds-NP_009752.3_CBS6413 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001523.1:602856-603527:- | gene-YBR193C_CENPK1137D | rna-NM_001178541.3_CENPK1137D | cds-NP_009752.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005472.1:717608-718279:- | gene-YBR193C_EthanolRed | rna-NM_001178541.3_EthanolRed | cds-NP_009752.3_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005536.1:608519-609190:- | gene-YBR193C_FaliES1 | rna-NM_001178541.3_FaliES1 | cds-NP_009752.3_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000023.1:2123-2794:- | gene-YBR193C_JAY291 | rna-NM_001178541.3_JAY291 | cds-NP_009752.3_JAY291 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005408.1:596989-597660:- | gene-YBR193C_MUCL30387 | rna-NM_001178541.3_MUCL30387 | cds-NP_009752.3_MUCL30387 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005440.1:614066-614737:- | gene-YBR193C_MUCL30388 | rna-NM_001178541.3_MUCL30388 | cds-NP_009752.3_MUCL30388 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005280.1:582605-583276:- | gene-YBR193C_MUCL39482 | rna-NM_001178541.3_MUCL39482 | cds-NP_009752.3_MUCL39482 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005424.1:592027-592698:- | gene-YBR193C_MUCL42920 | rna-NM_001178541.3_MUCL42920 | cds-NP_009752.3_MUCL42920 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011811.1:608879-609550:- | gene-YBR193C_NCIM3186 | rna-NM_001178541.3_NCIM3186 | cds-NP_009752.3_NCIM3186 | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005264.1:584713-585384:- | gene-YBR193C_NCYC1407 | rna-NM_001178541.3_NCYC1407 | cds-NP_009752.3_NCYC1407 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994141.1:597327-597998:- | gene-YBR193C_PE2H3 | rna-NM_001178541.3_PE2H3 | cds-NP_009752.3_PE2H3 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999873.1:595003-595674:- | gene-YBR193C_PE2H4 | rna-NM_001178541.3_PE2H4 | cds-NP_009752.3_PE2H4 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001134.8:609082-609753:- | gene-YBR193C_S288C | rna-NM_001178541.3_S288C | cds-NP_009752.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000080.1:16779-17450:- | gene-YBR193C_SA1 | rna-NM_001178541.3_SA1 | cds-NP_009752.3_SA1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005488.1:607529-608200:- | gene-YBR193C_ThermosaccDry | rna-NM_001178541.3_ThermosaccDry | cds-NP_009752.3_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005456.1:588702-589373:- | gene-YBR193C_VR1 | rna-NM_001178541.3_VR1 | cds-NP_009752.3_VR1 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000003.1:582145-582816:- | gene-YBR193C_ZTW1 | rna-NM_001178541.3_ZTW1 | cds-NP_009752.3_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047488.1:624054-624725:- | gene-YBR193C_Sparadoxus | rna-NM_001178541.3_Sparadoxus | cds-NP_009752.3_Sparadoxus | 90.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |