Gene name: MED7
Reference locus (S288C): YOL135C
Gene biotype: protein_coding
Description: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation
Top 10 interactors (score): RPO21 (0.999); SRB4 (0.999); RGR1 (0.999); SSN8 (0.999); MED6 (0.999); SRB7 (0.999); SOH1 (0.999); SSN3 (0.999); CSE2 (0.999); ROX3 (0.999); MED4 (0.999); SRB5 (0.999); NUT2 (0.999); SRB6 (0.999); MED11 (0.999); MED8 (0.999); RPB11 (0.998); SSN2 (0.998); SRB2 (0.998); GAL11 (0.998)
Homologues (species, bitscore): MED7 (Homo sapiens, 87.8); Med7 (Mus musculus, 87.4); med7 (Danio rerio, 87.0); med7 (Xenopus tropicalis, 85.5); MED7 (Drosophila melanogaster, 82.0); let-49 (Caenorhabditis elegans, 76.3); AT5G03500 (Arabidopsis thaliana, 96.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005309.1:58034-58702:- | gene-YOL135C_AKU4011 | rna-NM_001183389.1_AKU4011 | cds-NP_014506.1_AKU4011 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000172.1:23655-24323:- | gene-YOL135C_BG1 | rna-NM_001183389.1_BG1 | cds-NP_014506.1_BG1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005517.1:59311-59979:- | gene-YOL135C_Bruggeman | rna-NM_001183389.1_Bruggeman | cds-NP_014506.1_Bruggeman | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005533.1:58269-58937:- | gene-YOL135C_CAT1 | rna-NM_001183389.1_CAT1 | cds-NP_014506.1_CAT1 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005373.1:52510-53178:- | gene-YOL135C_CBS1585 | rna-NM_001183389.1_CBS1585 | cds-NP_014506.1_CBS1585 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005357.1:58357-59025:- | gene-YOL135C_CBS436 | rna-NM_001183389.1_CBS436 | cds-NP_014506.1_CBS436 | 99.2 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005341.1:52374-53042:- | gene-YOL135C_CBS6412 | rna-NM_001183389.1_CBS6412 | cds-NP_014506.1_CBS6412 | 99.8 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005325.1:58842-59510:- | gene-YOL135C_CBS6413 | rna-NM_001183389.1_CBS6413 | cds-NP_014506.1_CBS6413 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001536.1:69272-69940:- | gene-YOL135C_CENPK1137D | rna-NM_001183389.1_CENPK1137D | cds-NP_014506.1_CENPK1137D | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005485.1:56286-56954:- | gene-YOL135C_EthanolRed | rna-NM_001183389.1_EthanolRed | cds-NP_014506.1_EthanolRed | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005549.1:58315-58983:- | gene-YOL135C_FaliES1 | rna-NM_001183389.1_FaliES1 | cds-NP_014506.1_FaliES1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000329.1:23572-24240:+ | gene-YOL135C_JAY291 | rna-NM_001183389.1_JAY291 | cds-NP_014506.1_JAY291 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005421.1:63951-64619:- | gene-YOL135C_MUCL30387 | rna-NM_001183389.1_MUCL30387 | cds-NP_014506.1_MUCL30387 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005453.1:66945-67613:- | gene-YOL135C_MUCL30388 | rna-NM_001183389.1_MUCL30388 | cds-NP_014506.1_MUCL30388 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005293.1:60445-61113:- | gene-YOL135C_MUCL39482 | rna-NM_001183389.1_MUCL39482 | cds-NP_014506.1_MUCL39482 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005437.1:76331-76999:- | gene-YOL135C_MUCL42920 | rna-NM_001183389.1_MUCL42920 | cds-NP_014506.1_MUCL42920 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011824.1:69265-69933:- | gene-YOL135C_NCIM3186 | rna-NM_001183389.1_NCIM3186 | cds-NP_014506.1_NCIM3186 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005277.1:66484-67152:- | gene-YOL135C_NCYC1407 | rna-NM_001183389.1_NCYC1407 | cds-NP_014506.1_NCYC1407 | 99.8 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994154.1:44910-45578:- | gene-YOL135C_PE2H3 | rna-NM_001183389.1_PE2H3 | cds-NP_014506.1_PE2H3 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999886.1:61858-62526:- | gene-YOL135C_PE2H4 | rna-NM_001183389.1_PE2H4 | cds-NP_014506.1_PE2H4 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001147.6:69376-70044:- | gene-YOL135C_S288C | rna-NM_001183389.1_S288C | cds-NP_014506.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000001.1:42807-43475:- | gene-YOL135C_SA1 | rna-NM_001183389.1_SA1 | cds-NP_014506.1_SA1 | 99.2 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005501.1:57453-58121:- | gene-YOL135C_ThermosaccDry | rna-NM_001183389.1_ThermosaccDry | cds-NP_014506.1_ThermosaccDry | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005469.1:58108-58776:- | gene-YOL135C_VR1 | rna-NM_001183389.1_VR1 | cds-NP_014506.1_VR1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000031.1:57207-57875:- | gene-YOL135C_ZTW1 | rna-NM_001183389.1_ZTW1 | cds-NP_014506.1_ZTW1 | 99.7 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047501.1:59678-60346:- | gene-YOL135C_Sparadoxus | rna-NM_001183389.1_Sparadoxus | cds-NP_014506.1_Sparadoxus | 89.5 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |