MED4 (YOR174W)


Gene profile

Gene name: MED4
Reference locus (S288C): YOR174W
Gene biotype: protein_coding

Description: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation

Top 10 interactors (score): MED7 (0.999); SRB4 (0.999); SRB7 (0.999); CSE2 (0.999); MED8 (0.998); SOH1 (0.998); SRB6 (0.998); SRB5 (0.998); MED1 (0.997); MED6 (0.997); MED2 (0.996); SRB2 (0.996); NUT2 (0.995); RGR1 (0.994); MED11 (0.994); ROX3 (0.992); GAL11 (0.991); PGD1 (0.989); SIN4 (0.979); TAF14 (0.944)

Homologues (species, bitscore): Unknown

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005309.1:656386-657240:+ gene-YOR174W_AKU4011 rna-NM_001183593.3_AKU4011 cds-NP_014817.3_AKU4011 100.0 100.0 Verified 1 1 1 True True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000123.1:58140-58994:+ gene-YOR174W_BG1 rna-NM_001183593.3_BG1 cds-NP_014817.3_BG1 99.8 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005517.1:640459-641313:+ gene-YOR174W_Bruggeman rna-NM_001183593.3_Bruggeman cds-NP_014817.3_Bruggeman 100.0 100.0 Verified 1 1 1 True True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005533.1:640478-641332:+ gene-YOR174W_CAT1 rna-NM_001183593.3_CAT1 cds-NP_014817.3_CAT1 99.8 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005373.1:638881-639735:+ gene-YOR174W_CBS1585 rna-NM_001183593.3_CBS1585 cds-NP_014817.3_CBS1585 100.0 100.0 Verified 1 1 1 True True False False False
CBS436 GCA_001738355.1 Sake Asia CM005357.1:637175-638029:+ gene-YOR174W_CBS436 rna-NM_001183593.3_CBS436 cds-NP_014817.3_CBS436 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005341.1:636493-637347:+ gene-YOR174W_CBS6412 rna-NM_001183593.3_CBS6412 cds-NP_014817.3_CBS6412 100.0 100.0 Mismatch 1 1 1 True True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005325.1:645174-646028:+ gene-YOR174W_CBS6413 rna-NM_001183593.3_CBS6413 cds-NP_014817.3_CBS6413 100.0 100.0 Verified 1 1 1 True True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001536.1:658503-659357:+ gene-YOR174W_CENPK1137D rna-NM_001183593.3_CENPK1137D cds-NP_014817.3_CENPK1137D 100.0 100.0 Verified 1 1 1 True True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005485.1:632589-633443:+ gene-YOR174W_EthanolRed rna-NM_001183593.3_EthanolRed cds-NP_014817.3_EthanolRed 100.0 100.0 Verified 1 1 1 True True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005549.1:637442-638296:+ gene-YOR174W_FaliES1 rna-NM_001183593.3_FaliES1 cds-NP_014817.3_FaliES1 100.0 100.0 Verified 1 1 1 True True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000070.1:5246-6100:- gene-YOR174W_JAY291 rna-NM_001183593.3_JAY291 cds-NP_014817.3_JAY291 99.8 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005421.1:645266-646120:+ gene-YOR174W_MUCL30387 rna-NM_001183593.3_MUCL30387 cds-NP_014817.3_MUCL30387 100.0 100.0 Verified 1 1 1 True True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005453.1:652030-652884:+ gene-YOR174W_MUCL30388 rna-NM_001183593.3_MUCL30388 cds-NP_014817.3_MUCL30388 100.0 100.0 Verified 1 1 1 True True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005293.1:646722-647576:+ gene-YOR174W_MUCL39482 rna-NM_001183593.3_MUCL39482 cds-NP_014817.3_MUCL39482 100.0 100.0 Verified 1 1 1 True True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005437.1:656143-656997:+ gene-YOR174W_MUCL42920 rna-NM_001183593.3_MUCL42920 cds-NP_014817.3_MUCL42920 100.0 100.0 Verified 1 1 1 True True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011824.1:658636-659490:+ gene-YOR174W_NCIM3186 rna-NM_001183593.3_NCIM3186 cds-NP_014817.3_NCIM3186 99.8 100.0 Verified 1 1 1 True True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005277.1:646808-647662:+ gene-YOR174W_NCYC1407 rna-NM_001183593.3_NCYC1407 cds-NP_014817.3_NCYC1407 100.0 100.0 Verified 1 1 1 True True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994154.1:645319-646173:+ gene-YOR174W_PE2H3 rna-NM_001183593.3_PE2H3 cds-NP_014817.3_PE2H3 99.8 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999886.1:655696-656550:+ gene-YOR174W_PE2H4 rna-NM_001183593.3_PE2H4 cds-NP_014817.3_PE2H4 99.8 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001147.6:658747-659601:+ gene-YOR174W_S288C rna-NM_001183593.3_S288C cds-NP_014817.3_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000006.1:75305-76159:+ gene-YOR174W_SA1 rna-NM_001183593.3_SA1 cds-NP_014817.3_SA1 99.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005501.1:636625-637479:+ gene-YOR174W_ThermosaccDry rna-NM_001183593.3_ThermosaccDry cds-NP_014817.3_ThermosaccDry 100.0 100.0 Verified 1 1 1 True True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005469.1:700322-701176:+ gene-YOR174W_VR1 rna-NM_001183593.3_VR1 cds-NP_014817.3_VR1 100.0 100.0 Verified 1 1 1 True True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000032.1:370076-370930:+ gene-YOR174W_ZTW1 rna-NM_001183593.3_ZTW1 cds-NP_014817.3_ZTW1 100.0 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047501.1:641601-642455:+ gene-YOR174W_Sparadoxus rna-NM_001183593.3_Sparadoxus cds-NP_014817.3_Sparadoxus 87.2 100.0 Verified 1 1 1 False True False False False

Additional files