Gene name: MED2
Reference locus (S288C): YDL005C
Gene biotype: protein_coding
Description: Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; relocalizes to the cytosol in response to hypoxia
Top 10 interactors (score): GAL11 (0.999); PGD1 (0.999); SRB5 (0.998); SIN4 (0.997); SRB4 (0.997); SRB2 (0.996); MED7 (0.996); NUT1 (0.996); RGR1 (0.996); MED4 (0.996); MED8 (0.995); NUT2 (0.994); MED1 (0.993); SSN3 (0.993); CSE2 (0.992); SOH1 (0.989); SRB6 (0.989); MED11 (0.988); SRB8 (0.986); SSN2 (0.986)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005298.1:426270-427556:- | gene-YDL005C_AKU4011 | rna-NM_001180064.3_AKU4011 | cds-NP_010279.3_AKU4011 | 98.5 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000102.1:121851-123140:+ | gene-YDL005C_BG1 | rna-NM_001180064.3_BG1 | cds-NP_010279.3_BG1 | 98.6 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005506.1:446869-448158:- | gene-YDL005C_Bruggeman | rna-NM_001180064.3_Bruggeman | cds-NP_010279.3_Bruggeman | 98.8 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005522.1:439716-441005:- | gene-YDL005C_CAT1 | rna-NM_001180064.3_CAT1 | cds-NP_010279.3_CAT1 | 98.7 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005362.1:423481-424767:- | gene-YDL005C_CBS1585 | rna-NM_001180064.3_CBS1585 | cds-NP_010279.3_CBS1585 | 98.3 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005346.1:440244-441533:- | gene-YDL005C_CBS436 | rna-NM_001180064.3_CBS436 | cds-NP_010279.3_CBS436 | 98.8 | 99.5 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005330.1:420729-422015:- | gene-YDL005C_CBS6412 | rna-NM_001180064.3_CBS6412 | cds-NP_010279.3_CBS6412 | 98.5 | 99.3 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005314.1:442419-443705:- | gene-YDL005C_CBS6413 | rna-NM_001180064.3_CBS6413 | cds-NP_010279.3_CBS6413 | 98.5 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001525.1:439877-441172:- | gene-YDL005C_CENPK1137D | rna-NM_001180064.3_CENPK1137D | cds-NP_010279.3_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005474.1:435103-436389:- | gene-YDL005C_EthanolRed | rna-NM_001180064.3_EthanolRed | cds-NP_010279.3_EthanolRed | 98.6 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005538.1:441271-442560:- | gene-YDL005C_FaliES1 | rna-NM_001180064.3_FaliES1 | cds-NP_010279.3_FaliES1 | 98.6 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000442.1:29480-30769:+ | gene-YDL005C_JAY291 | rna-NM_001180064.3_JAY291 | cds-NP_010279.3_JAY291 | 98.6 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005410.1:440740-442029:- | gene-YDL005C_MUCL30387 | rna-NM_001180064.3_MUCL30387 | cds-NP_010279.3_MUCL30387 | 98.8 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005442.1:431202-432491:- | gene-YDL005C_MUCL30388 | rna-NM_001180064.3_MUCL30388 | cds-NP_010279.3_MUCL30388 | 98.8 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005282.1:424850-426136:- | gene-YDL005C_MUCL39482 | rna-NM_001180064.3_MUCL39482 | cds-NP_010279.3_MUCL39482 | 98.4 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005426.1:346275-347564:- | gene-YDL005C_MUCL42920 | rna-NM_001180064.3_MUCL42920 | cds-NP_010279.3_MUCL42920 | 98.8 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011813.1:440937-442232:- | gene-YDL005C_NCIM3186 | rna-NM_001180064.3_NCIM3186 | cds-NP_010279.3_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005266.1:423772-425058:- | gene-YDL005C_NCYC1407 | rna-NM_001180064.3_NCYC1407 | cds-NP_010279.3_NCYC1407 | 98.4 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994143.1:439348-440637:- | gene-YDL005C_PE2H3 | rna-NM_001180064.3_PE2H3 | cds-NP_010279.3_PE2H3 | 98.6 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999875.1:438707-439996:- | gene-YDL005C_PE2H4 | rna-NM_001180064.3_PE2H4 | cds-NP_010279.3_PE2H4 | 98.6 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001136.10:441014-442309:- | gene-YDL005C_S288C | rna-NM_001180064.3_S288C | cds-NP_010279.3_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000099.1:29669-30958:+ | gene-YDL005C_SA1 | rna-NM_001180064.3_SA1 | cds-NP_010279.3_SA1 | 98.6 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005490.1:440751-442037:- | gene-YDL005C_ThermosaccDry | rna-NM_001180064.3_ThermosaccDry | cds-NP_010279.3_ThermosaccDry | 98.4 | 99.3 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005458.1:445205-446494:- | gene-YDL005C_VR1 | rna-NM_001180064.3_VR1 | cds-NP_010279.3_VR1 | 98.6 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000006.1:438645-439934:- | gene-YDL005C_ZTW1 | rna-NM_001180064.3_ZTW1 | cds-NP_010279.3_ZTW1 | 98.6 | 99.5 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047490.1:443030-444289:- | gene-YDL005C_Sparadoxus | rna-NM_001180064.3_Sparadoxus | cds-NP_010279.3_Sparadoxus | 84.5 | 96.9 | Verified | 1 | 1 | 1 | False | True | False | False | False |