Gene name: MEC3
Reference locus (S288C): YLR288C
Gene biotype: protein_coding
Description: DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric complex (Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded onto partial duplex DNA by a clamp loader complex; homolog of human and S. pombe Hus1
Top 10 interactors (score): DDC1 (0.999); RAD17 (0.999); RAD24 (0.986); MEC1 (0.986); RAD9 (0.968); SGS1 (0.942); RAD53 (0.934); RFA2 (0.931); RFA1 (0.922); ELG1 (0.916); CDC13 (0.899); LCD1 (0.893); MRC1 (0.893); RFC2 (0.887); CSM3 (0.883); POL32 (0.879); RFC5 (0.874); EXO1 (0.872); DPB11 (0.864); TEL1 (0.849)
Homologues (species, bitscore): Unknown
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005306.1:662279-663703:- | gene-YLR288C_AKU4011 | rna-NM_001182176.1_AKU4011 | cds-NP_013391.1_AKU4011 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000170.1:68988-70412:+ | gene-YLR288C_BG1 | rna-NM_001182176.1_BG1 | cds-NP_013391.1_BG1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005514.1:697459-698883:- | gene-YLR288C_Bruggeman | rna-NM_001182176.1_Bruggeman | cds-NP_013391.1_Bruggeman | 98.8 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005530.1:696028-697452:- | gene-YLR288C_CAT1 | rna-NM_001182176.1_CAT1 | cds-NP_013391.1_CAT1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005370.1:697215-698639:- | gene-YLR288C_CBS1585 | rna-NM_001182176.1_CBS1585 | cds-NP_013391.1_CBS1585 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005354.1:681806-683230:- | gene-YLR288C_CBS436 | rna-NM_001182176.1_CBS436 | cds-NP_013391.1_CBS436 | 98.5 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005338.1:659848-661272:- | gene-YLR288C_CBS6412 | rna-NM_001182176.1_CBS6412 | cds-NP_013391.1_CBS6412 | 99.6 | 100.0 | Mismatch | 1 | 1 | 1 | True | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005322.1:697880-699304:- | gene-YLR288C_CBS6413 | rna-NM_001182176.1_CBS6413 | cds-NP_013391.1_CBS6413 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001533.1:698078-699502:- | gene-YLR288C_CENPK1137D | rna-NM_001182176.1_CENPK1137D | cds-NP_013391.1_CENPK1137D | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005482.1:655558-656982:- | gene-YLR288C_EthanolRed | rna-NM_001182176.1_EthanolRed | cds-NP_013391.1_EthanolRed | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005546.1:684758-686182:- | gene-YLR288C_FaliES1 | rna-NM_001182176.1_FaliES1 | cds-NP_013391.1_FaliES1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000359.1:19588-21012:+ | gene-YLR288C_JAY291 | rna-NM_001182176.1_JAY291 | cds-NP_013391.1_JAY291 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005418.1:697350-698774:- | gene-YLR288C_MUCL30387 | rna-NM_001182176.1_MUCL30387 | cds-NP_013391.1_MUCL30387 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005450.1:702931-704355:- | gene-YLR288C_MUCL30388 | rna-NM_001182176.1_MUCL30388 | cds-NP_013391.1_MUCL30388 | 98.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005290.1:698446-699870:- | gene-YLR288C_MUCL39482 | rna-NM_001182176.1_MUCL39482 | cds-NP_013391.1_MUCL39482 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005434.1:693599-695023:- | gene-YLR288C_MUCL42920 | rna-NM_001182176.1_MUCL42920 | cds-NP_013391.1_MUCL42920 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011821.1:713454-714878:- | gene-YLR288C_NCIM3186 | rna-NM_001182176.1_NCIM3186 | cds-NP_013391.1_NCIM3186 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005274.1:707777-709201:- | gene-YLR288C_NCYC1407 | rna-NM_001182176.1_NCYC1407 | cds-NP_013391.1_NCYC1407 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994151.1:695575-696999:- | gene-YLR288C_PE2H3 | rna-NM_001182176.1_PE2H3 | cds-NP_013391.1_PE2H3 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999883.1:695319-696743:- | gene-YLR288C_PE2H4 | rna-NM_001182176.1_PE2H4 | cds-NP_013391.1_PE2H4 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001144.5:713480-714904:- | gene-YLR288C_S288C | rna-NM_001182176.1_S288C | cds-NP_013391.1_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000039.1:69786-71210:+ | gene-YLR288C_SA1 | rna-NM_001182176.1_SA1 | cds-NP_013391.1_SA1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005498.1:686653-688077:- | gene-YLR288C_ThermosaccDry | rna-NM_001182176.1_ThermosaccDry | cds-NP_013391.1_ThermosaccDry | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005466.1:698540-699964:- | gene-YLR288C_VR1 | rna-NM_001182176.1_VR1 | cds-NP_013391.1_VR1 | 98.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000025.1:25088-26512:- | gene-YLR288C_ZTW1 | rna-NM_001182176.1_ZTW1 | cds-NP_013391.1_ZTW1 | 99.6 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047498.1:672722-674143:- | gene-YLR288C_Sparadoxus | rna-NM_001182176.1_Sparadoxus | cds-NP_013391.1_Sparadoxus | 91.5 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |