MDV1 (YJL112W)


Gene profile

Gene name: MDV1
Reference locus (S288C): YJL112W
Gene biotype: protein_coding

Description: Peripheral protein of cytosolic face of mitochondrial outer membrane; required for mitochondrial fission; interacts with Fis1p and with the self-assembled oligomeric form of the dynamin-related GTPase Dnm1p; contains WD repeats; MDV1 has a paralog, CAF4, that arose from the whole genome duplication

Top 10 interactors (score): CAF4 (0.999); FIS1 (0.999); DNM1 (0.999); FZO1 (0.974); MGM1 (0.913); UGO1 (0.805); CDC73 (0.77); CIA1 (0.757); CYC7 (0.68); CTR9 (0.67); SNF4 (0.645); GCD7 (0.645); VPS1 (0.632); CYC1 (0.621); PAF1 (0.613); LEO1 (0.611); SPO11 (0.579); EST2 (0.545); PEX11 (0.531); POR1 (0.525)

Homologues (species, bitscore): FBXW7 (Homo sapiens, 124.8); Fbxw7 (Mus musculus, 124.4); FBXW7 (Danio rerio, 123.2); fbxw7 (Xenopus tropicalis, 124.8); ago (Drosophila melanogaster, 120.2); sel-10 (Caenorhabditis elegans, 107.8); AT1G11160 (Arabidopsis thaliana, 97.1)

External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser


Comparative analysis of strains

Search table

strain assembly application macro_region gene_coord geneID rnaID protID %id %cov_exon status copyNumber copyID nORFs match_ref_CDS validORF missing_startCodon missing_stopCodon outOfFrame_stopCodon
AKU4011 GCA_001738255.1 Sake Asia CM005304.1:188047-190191:+ gene-YJL112W_AKU4011 rna-NM_001181545.2_AKU4011 cds-NP_012423.1_AKU4011 99.6 100.0 Verified 1 1 1 False True False False False
BG1 GCA_001932575.1 Bioethanol South America MSHP01000190.1:424252-426396:- gene-YJL112W_BG1 rna-NM_001181545.2_BG1 cds-NP_012423.1_BG1 99.7 100.0 Verified 1 1 1 False True False False False
Bruggeman GCA_001738585.1 Bread Not Applicable CM005512.1:199481-201625:+ gene-YJL112W_Bruggeman rna-NM_001181545.2_Bruggeman cds-NP_012423.1_Bruggeman 99.7 100.0 Verified 1 1 1 False True False False False
CAT1 GCA_001738705.1 Bioethanol South America CM005528.1:204391-206535:+ gene-YJL112W_CAT1 rna-NM_001181545.2_CAT1 cds-NP_012423.1_CAT1 99.6 100.0 Verified 1 1 1 False True False False False
CBS1585 GCA_001738375.1 Sake Asia CM005368.1:199708-201852:+ gene-YJL112W_CBS1585 rna-NM_001181545.2_CBS1585 cds-NP_012423.1_CBS1585 99.7 100.0 Verified 1 1 1 False True False False False
CBS436 GCA_001738355.1 Sake Asia CM005352.1:217806-219950:+ gene-YJL112W_CBS436 rna-NM_001181545.2_CBS436 cds-NP_012423.1_CBS436 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6412 GCA_001738345.1 Sake Asia CM005336.1:188805-190949:+ gene-YJL112W_CBS6412 rna-NM_001181545.2_CBS6412 cds-NP_012423.1_CBS6412 99.7 100.0 Mismatch 1 1 1 False True False False False
CBS6413 GCA_001738265.1 Sake Asia CM005320.1:190160-192304:+ gene-YJL112W_CBS6413 rna-NM_001181545.2_CBS6413 cds-NP_012423.1_CBS6413 99.7 100.0 Verified 1 1 1 False True False False False
CENPK1137D GCA_000269885.1 Laboratory Not Applicable CM001531.1:187766-189910:+ gene-YJL112W_CENPK1137D rna-NM_001181545.2_CENPK1137D cds-NP_012423.1_CENPK1137D 99.7 100.0 Verified 1 1 1 False True False False False
EthanolRed GCA_001738615.1 Bioethanol Asia CM005480.1:191897-194041:+ gene-YJL112W_EthanolRed rna-NM_001181545.2_EthanolRed cds-NP_012423.1_EthanolRed 99.7 100.0 Verified 1 1 1 False True False False False
FaliES1 GCA_001738715.1 Bioethanol Asia CM005544.1:203473-205617:+ gene-YJL112W_FaliES1 rna-NM_001181545.2_FaliES1 cds-NP_012423.1_FaliES1 99.7 100.0 Verified 1 1 1 False True False False False
JAY291 GCA_000182315.2 Bioethanol South America ACFL01000138.1:1100-3244:+ gene-YJL112W_JAY291 rna-NM_001181545.2_JAY291 cds-NP_012423.1_JAY291 99.7 100.0 Verified 1 1 1 False True False False False
MUCL30387 GCA_001738515.1 Bread Europe CM005416.1:201749-203893:+ gene-YJL112W_MUCL30387 rna-NM_001181545.2_MUCL30387 cds-NP_012423.1_MUCL30387 99.5 100.0 Verified 1 1 1 False True False False False
MUCL30388 GCA_001738495.1 Bread Europe CM005448.1:197827-199971:+ gene-YJL112W_MUCL30388 rna-NM_001181545.2_MUCL30388 cds-NP_012423.1_MUCL30388 99.7 100.0 Verified 1 1 1 False True False False False
MUCL39482 GCA_001738235.1 Sake Asia CM005288.1:192465-194609:+ gene-YJL112W_MUCL39482 rna-NM_001181545.2_MUCL39482 cds-NP_012423.1_MUCL39482 99.7 100.0 Verified 1 1 1 False True False False False
MUCL42920 GCA_001738485.1 Bread Europe CM005432.1:198648-200792:+ gene-YJL112W_MUCL42920 rna-NM_001181545.2_MUCL42920 cds-NP_012423.1_MUCL42920 99.6 100.0 Verified 1 1 1 False True False False False
NCIM3186 GCA_001029075.1 Bioethanol Asia CP011819.1:205284-207428:+ gene-YJL112W_NCIM3186 rna-NM_001181545.2_NCIM3186 cds-NP_012423.1_NCIM3186 99.5 100.0 Verified 1 1 1 False True False False False
NCYC1407 GCA_001738225.1 Sake Asia CM005272.1:191155-193299:+ gene-YJL112W_NCYC1407 rna-NM_001181545.2_NCYC1407 cds-NP_012423.1_NCYC1407 99.6 100.0 Verified 1 1 1 False True False False False
PE2H3 GCA_905220325.1 Bioethanol South America HG994149.1:203524-205668:+ gene-YJL112W_PE2H3 rna-NM_001181545.2_PE2H3 cds-NP_012423.1_PE2H3 99.7 100.0 Verified 1 1 1 False True False False False
PE2H4 GCA_905220315.1 Bioethanol South America LR999881.1:203168-205312:+ gene-YJL112W_PE2H4 rna-NM_001181545.2_PE2H4 cds-NP_012423.1_PE2H4 99.7 100.0 Verified 1 1 1 False True False False False
S288C GCF_000146045.2 Laboratory Not applicable NC_001142.9:205305-207449:+ gene-YJL112W_S288C rna-NM_001181545.2_S288C cds-NP_012423.1_S288C 100.0 100.0 Verified 1 1 1 True True False False False
SA1 GCA_004114265.1 Bioethanol South America SDIA01000003.1:1030-3174:+ gene-YJL112W_SA1 rna-NM_001181545.2_SA1 cds-NP_012423.1_SA1 98.8 100.0 Verified 1 1 1 False True False False False
ThermosaccDry GCA_001738605.1 Bioethanol Asia CM005496.1:196883-199027:+ gene-YJL112W_ThermosaccDry rna-NM_001181545.2_ThermosaccDry cds-NP_012423.1_ThermosaccDry 99.7 100.0 Verified 1 1 1 False True False False False
VR1 GCA_001738595.1 Bioethanol South America CM005464.1:197303-199447:+ gene-YJL112W_VR1 rna-NM_001181545.2_VR1 cds-NP_012423.1_VR1 99.6 100.0 Verified 1 1 1 False True False False False
ZTW1 GCA_000308935.1 Bioethanol Asia AMDD01000021.1:178246-180390:+ gene-YJL112W_ZTW1 rna-NM_001181545.2_ZTW1 cds-NP_012423.1_ZTW1 99.9 100.0 Verified 1 1 1 True True False False False
Sparadoxus GCF_002079055.1 Not applicable Not applicable NC_047496.1:202294-204429:+ gene-YJL112W_Sparadoxus rna-NM_001181545.2_Sparadoxus cds-NP_012423.1_Sparadoxus 89.1 99.5 Verified 1 1 1 False True False False False

Additional files