Gene name: MDS3
Reference locus (S288C): YGL197W
Gene biotype: protein_coding
Description: Putative component of the TOR regulatory pathway; negative regulator of early meiotic gene expression; required, with Pmd1p, for growth under alkaline conditions; has an N-terminal kelch-like domain; MDS3 has a paralog, PMD1, that arose from the whole genome duplication
Top 10 interactors (score): SUV3 (0.866); CDC25 (0.823); YBR225W (0.797); SAP185 (0.774); SIT4 (0.766); NUP85 (0.68); RIM13 (0.68); CLB3 (0.675); GCN1 (0.67); PSE1 (0.657); PKC1 (0.654); RIM101 (0.643); PMD1 (0.624); YTA6 (0.619); GDS1 (0.619); CUB1 (0.618); VPS70 (0.617); BIO3 (0.569); YBR139W (0.565); TOR1 (0.555)
Homologues (species, bitscore): FBXO42 (Homo sapiens, 54.7); Fbxo42 (Mus musculus, 54.7); fbxo42 (Xenopus tropicalis, 54.7)
External links:
Saccharomyces genome database (SGD)
STRING database
BioGRID
UniProt Knowledgebase
Kyoto encyclopedia of genes and genomes (KEGG)
Reactome
UCSC Genome Browser
| strain | assembly | application | macro_region | gene_coord | geneID | rnaID | protID | %id | %cov_exon | status | copyNumber | copyID | nORFs | match_ref_CDS | validORF | missing_startCodon | missing_stopCodon | outOfFrame_stopCodon |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AKU4011 | GCA_001738255.1 | Sake | Asia | CM005301.1:127234-131697:+ | gene-YGL197W_AKU4011 | rna-NM_001181062.2_AKU4011 | cds-NP_011318.2_AKU4011 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| BG1 | GCA_001932575.1 | Bioethanol | South America | MSHP01000132.1:278723-283186:- | gene-YGL197W_BG1 | rna-NM_001181062.2_BG1 | cds-NP_011318.2_BG1 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Bruggeman | GCA_001738585.1 | Bread | Not Applicable | CM005509.1:128276-132739:+ | gene-YGL197W_Bruggeman | rna-NM_001181062.2_Bruggeman | cds-NP_011318.2_Bruggeman | 99.0 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CAT1 | GCA_001738705.1 | Bioethanol | South America | CM005525.1:125090-129554:+ | gene-YGL197W_CAT1 | rna-NM_001181062.2_CAT1 | cds-NP_011318.2_CAT1 | 98.9 | 100.0 | Unannotated | 1 | 1 | 0 | False | False | False | True | False |
| CBS1585 | GCA_001738375.1 | Sake | Asia | CM005365.1:130379-134842:+ | gene-YGL197W_CBS1585 | rna-NM_001181062.2_CBS1585 | cds-NP_011318.2_CBS1585 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CBS436 | GCA_001738355.1 | Sake | Asia | CM005349.1:125354-129817:+ | gene-YGL197W_CBS436 | rna-NM_001181062.2_CBS436 | cds-NP_011318.2_CBS436 | 98.8 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6412 | GCA_001738345.1 | Sake | Asia | CM005333.1:117149-121612:+ | gene-YGL197W_CBS6412 | rna-NM_001181062.2_CBS6412 | cds-NP_011318.2_CBS6412 | 99.4 | 100.0 | Mismatch | 1 | 1 | 1 | False | True | False | False | False |
| CBS6413 | GCA_001738265.1 | Sake | Asia | CM005317.1:124684-129147:+ | gene-YGL197W_CBS6413 | rna-NM_001181062.2_CBS6413 | cds-NP_011318.2_CBS6413 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| CENPK1137D | GCA_000269885.1 | Laboratory | Not Applicable | CM001528.1:124877-129340:+ | gene-YGL197W_CENPK1137D | rna-NM_001181062.2_CENPK1137D | cds-NP_011318.2_CENPK1137D | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| EthanolRed | GCA_001738615.1 | Bioethanol | Asia | CM005477.1:117216-121679:+ | gene-YGL197W_EthanolRed | rna-NM_001181062.2_EthanolRed | cds-NP_011318.2_EthanolRed | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| FaliES1 | GCA_001738715.1 | Bioethanol | Asia | CM005541.1:118218-122681:+ | gene-YGL197W_FaliES1 | rna-NM_001181062.2_FaliES1 | cds-NP_011318.2_FaliES1 | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| JAY291 | GCA_000182315.2 | Bioethanol | South America | ACFL01000397.1:43531-47994:+ | gene-YGL197W_JAY291 | rna-NM_001181062.2_JAY291 | cds-NP_011318.2_JAY291 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30387 | GCA_001738515.1 | Bread | Europe | CM005413.1:126713-131176:+ | gene-YGL197W_MUCL30387 | rna-NM_001181062.2_MUCL30387 | cds-NP_011318.2_MUCL30387 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL30388 | GCA_001738495.1 | Bread | Europe | CM005445.1:129051-133514:+ | gene-YGL197W_MUCL30388 | rna-NM_001181062.2_MUCL30388 | cds-NP_011318.2_MUCL30388 | 99.1 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL39482 | GCA_001738235.1 | Sake | Asia | CM005285.1:127380-131843:+ | gene-YGL197W_MUCL39482 | rna-NM_001181062.2_MUCL39482 | cds-NP_011318.2_MUCL39482 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| MUCL42920 | GCA_001738485.1 | Bread | Europe | CM005429.1:129994-134457:+ | gene-YGL197W_MUCL42920 | rna-NM_001181062.2_MUCL42920 | cds-NP_011318.2_MUCL42920 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCIM3186 | GCA_001029075.1 | Bioethanol | Asia | CP011816.1:124698-129161:+ | gene-YGL197W_NCIM3186 | rna-NM_001181062.2_NCIM3186 | cds-NP_011318.2_NCIM3186 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| NCYC1407 | GCA_001738225.1 | Sake | Asia | CM005269.1:118864-123327:+ | gene-YGL197W_NCYC1407 | rna-NM_001181062.2_NCYC1407 | cds-NP_011318.2_NCYC1407 | 99.4 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H3 | GCA_905220325.1 | Bioethanol | South America | HG994146.1:120859-125322:+ | gene-YGL197W_PE2H3 | rna-NM_001181062.2_PE2H3 | cds-NP_011318.2_PE2H3 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| PE2H4 | GCA_905220315.1 | Bioethanol | South America | LR999878.1:120407-124870:+ | gene-YGL197W_PE2H4 | rna-NM_001181062.2_PE2H4 | cds-NP_011318.2_PE2H4 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| S288C | GCF_000146045.2 | Laboratory | Not applicable | NC_001139.9:124698-129161:+ | gene-YGL197W_S288C | rna-NM_001181062.2_S288C | cds-NP_011318.2_S288C | 100.0 | 100.0 | Verified | 1 | 1 | 1 | True | True | False | False | False |
| SA1 | GCA_004114265.1 | Bioethanol | South America | SDIA01000002.1:246344-250807:- | gene-YGL197W_SA1 | rna-NM_001181062.2_SA1 | cds-NP_011318.2_SA1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ThermosaccDry | GCA_001738605.1 | Bioethanol | Asia | CM005493.1:118478-122941:+ | gene-YGL197W_ThermosaccDry | rna-NM_001181062.2_ThermosaccDry | cds-NP_011318.2_ThermosaccDry | 99.3 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| VR1 | GCA_001738595.1 | Bioethanol | South America | CM005461.1:125766-130229:+ | gene-YGL197W_VR1 | rna-NM_001181062.2_VR1 | cds-NP_011318.2_VR1 | 98.9 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| ZTW1 | GCA_000308935.1 | Bioethanol | Asia | AMDD01000014.1:117015-121478:+ | gene-YGL197W_ZTW1 | rna-NM_001181062.2_ZTW1 | cds-NP_011318.2_ZTW1 | 99.5 | 100.0 | Verified | 1 | 1 | 1 | False | True | False | False | False |
| Sparadoxus | GCF_002079055.1 | Not applicable | Not applicable | NC_047493.1:123911-128365:+ | gene-YGL197W_Sparadoxus | rna-NM_001181062.2_Sparadoxus | cds-NP_011318.2_Sparadoxus | 89.3 | 99.7 | Verified | 1 | 1 | 1 | False | True | False | False | False |